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1 tetradecanol

Manufactured by Thermo Fisher Scientific
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Sourced in Belgium

1-tetradecanol is a long-chain primary alcohol with the chemical formula CH3(CH2)12CH2OH. It is a solid, waxy substance at room temperature. The primary function of 1-tetradecanol is as a chemical intermediate in the production of various compounds, including surfactants, lubricants, and personal care products.

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Lab products found in correlation

Agilent 6890, by Agilent Technologies (1 mentions) 1 octanol, by Merck Group (1 mentions) 1 dodecanol, by Thermo Fisher Scientific (1 mentions)

2 protocols using 1 tetradecanol

1

Synthesis and Purification of Acetylated Alcohols

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Hydroxyl groups of 1-tetradecanol (Acros Organics, Geel, Belgium), and geranylgeraniol (Toronto Research Chemicals, Toronto, Canada) were acetylated by acetic anhydride and pyridine to obtain the corresponding acetates (Zada et al., 2004 (link)). Myristyl acetate was purified by vacuum distillation using glass oven Kugelrohr (Buchi, Flawil, Switzerland) at 115°C/1 mm, 90% yield, >98% purity. Geranylgeranyl acetate was purified by column chromatography (SiO2/ether:hexane 95:5) 80% yield, 96% purity. Purity was determined by GC (Agilent 6890) with FID detector.
Brent C.S., Byers J.A, & Levi-Zada A. (2017). An insect anti-antiaphrodisiac. eLife, 6, e24063.
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2

Identification of Ion Channel Modulators

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Reagents 0.6% Ethanol (104mM, KOPTEC) was directly added to the external solution. 1-Octanol (Sigma), 1-Dodecanol (Acros Organics), and 1-Tetradecanol (Acros Organics), and FIPI (Calbiochem), were made as stock solutions in DMSO, then added into external solution with the sonication using Avanti Sonicator (model#G112SP1T_B) in the final concentrations of 150 μM, 20 μM, 1 μM, and 1 μM, respectively. The residual DMSO amount in the bath was maintained <0.05%. 200 μM Quinidine was directly added into the external solution with sonication. All the salts for internal/external solutions were purchased from either Sigma or Fisher Scientific.
Chung H.W., Petersen E.N., Cabanos C., Murphy K.R., Arif Pavel M., Hansen A.S., Ja W.W, & Hansen S.B. (2018). A Molecular Target for an Alcohol Chain Length Cutoff.. Journal of molecular biology, 431(2), 196-209.
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