Analyze 11

Manufactured by PerkinElmer

Sourced in United States

The Analyze 11.0 is a high-performance liquid chromatography (HPLC) system designed for analytical and preparative applications. It features a modular design, allowing for customization and flexibility to meet the specific needs of users. The core function of the Analyze 11.0 is to separate, identify, and quantify components in a complex mixture.

Automatically generated - may contain errors

Lab products found in correlation

Quantum fx ct scanner, by PerkinElmer (2 mentions) Quantum fx μct scanner, by PerkinElmer (1 mentions) Quantum gx, by PerkinElmer (1 mentions)

4 protocols using analyze 11

Micro-CT Analysis of Rat Knee Joints

Check if the same lab product or an alternative is used in the 5 most similar protocols

Knee joints were imaged post mortem using a Quantum FX µ-CT scanner (PerkinElmer, Waltham, MA, USA) with parameters time = 3 min, isotropic voxel size = 30 µm³, tube voltage = 90 kV, and tube current = 180 µA. 3D images were obtained and reconstructed to serial 2D images using software Analyze 11.0 (PerkinElmer, Waltham, MA, USA). Serial 2D or 3D scans of the femur, tibia and patella were made and 2D scans were used to evaluate subchondral sclerosis, osteophytes, bone cysts and loose bodies using ImageJ software (ImageJ, 1.47v, NIH, Bethesda, USA) according to a multi-modality scoring system for rats [17 (link)].

Rudnik-Jansen I., Woike N., de Jong S., Versteeg S., Kik M., Emans P., Mihov G., Thies J., Eijkelkamp N., Tryfonidou M, & Creemers L. (2019). Applicability of a Modified Rat Model of Acute Arthritis for Long-Term Testing of Drug Delivery Systems. Pharmaceutics, 11(2), 70.

+ Open protocol

+ Expand

Micro-CT Imaging of Rat Osteoarthritis

Check if the same lab product or an alternative is used in the 5 most similar protocols

All rats were imaged directly after CO₂/O₂ asphyxiation, using a Quantum FX μCT scanner (PerkinElmer, Waltham, MA) with parameters time = 3 min, isotropic voxel size = 30 μm³, tube voltage of 90 kV, and tube current = 180 μA. 3D reconstructed images were obtained, and serial 2D images were reconstructed using software Analyze 11.0 (PerkinElmer; RRID:SCR_009120). ImageJ software (ImageJ; RRID:SCR_003070) was used for all analyses. Serial 2D scans were evaluated for subchondral sclerosis, osteophytes, bone cysts, and loose bodies according to a multi‐modality scoring system evaluated previously (Panahifar et al., 2014). Joint alignment was evaluated using sagittal serial 2D scans. Periarticular dystrophic calcifications were quantified by the mean average of each pixel value above soft tissue pixel value of each μCT scan, based on histograms representing air, soft tissue, and calcified tissue values. To obtain comparable region of interests, the same distance from growth plate to the lower end of tibia on the scan was measured.

Rudnik‐Jansen I., Tellegen A.R., Pouran B., Schrijver K., Meij B.P., Emans P.J., de Gendt E., Thomas R.E., Kik M.J., de Visser H.M., Weinans H., Egas A., van Maarseveen E., Woike N., Mihov G., Thies J., Tryfonidou M.A, & Creemers L.B. (2019). Local controlled release of corticosteroids extends surgically induced joint instability by inhibiting tissue healing. British Journal of Pharmacology, 176(20), 4050-4064.

+ Open protocol

+ Expand

Micro-CT Analysis of Knee Joint

Check if the same lab product or an alternative is used in the 5 most similar protocols

The knee joint was fixed in 4% paraformaldehyde for 24 h and subjected to micro-CT (Micro-CT, QuantumGX, PerkinElmer, USA). The parameters were as follows: time 14 min, tube voltage 90 kV, and tube current 88uA. Sequential 2D images were reconstructed from the 3D images using the Analyze 11.0 software (PerkinElmer, Waltham, MA, USA).

Li J., Liu N., Huang Z., Wang W., Hou D, & Wang W. (2021). Intra-articular injection of loaded sPL sustained-release microspheres inhibits osteoarthritis and promotes cartilaginous repairs. Journal of Orthopaedic Surgery and Research, 16, 646.

+ Open protocol

+ Expand

Comprehensive Micro-CT Imaging and Analysis of Rat Knee

Check if the same lab product or an alternative is used in the 5 most similar protocols

Directly after CO₂/O₂ asphyxiation, animals were imaged using a Quantum FX µ-CT scanner (PerkinElmer, Waltham, MA) with parameters time = 3 min, isotropic voxel size = 30 µm³, tube voltage of 90 kV, tube current = 180 µA. Serial 2 D images were reconstructed from the obtained 3 D reconstructed images using software Analyze 11.0 (PerkinElmer, Waltham, MA, USA). ImageJ software (ImageJ, 1.47v, NIH, Bethesda, USA) was used for all analyses. Serial 2 D scans of the femur, tibia, and patella were evaluated for subchondral sclerosis, osteophytes, bone cysts and loose bodies according to a multi-modality scoring system for rats evaluated previously (Panahifar et al., 2014 (link)).

Rudnik-Jansen I., Schrijver K., Woike N., Tellegen A., Versteeg S., Emans P., Mihov G., Thies J., Eijkelkamp N., Tryfonidou M, & Creemers L. (2019). Intra-articular injection of triamcinolone acetonide releasing biomaterial microspheres inhibits pain and inflammation in an acute arthritis model. Drug Delivery, 26(1), 226-236.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!