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Rage sirna

Manufactured by GenePharma
Sourced in China

RAGE siRNA is a laboratory product designed for gene silencing applications. It is a small interfering RNA (siRNA) targeting the Receptor for Advanced Glycation End Products (RAGE) gene. The core function of RAGE siRNA is to induce post-transcriptional gene silencing of the RAGE gene, thereby reducing the expression of the RAGE protein.

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2 protocols using rage sirna

1

Silencing RAGE and HSF1 in HUVECs

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RAGE siRNA (5′-GGAAUGGAAAGGAGACCAATT-3′), HSF1 siRNA (5′-GGAAAGUGGUC CACAUCGATT-3′), and negative control siRNA (5′-UUCUCCGAACGUGUCACGUTT-3′) were purchased from GenePharma Co., Ltd (Shanghai, China). HUVECs were transfected with siRNA using siRNA-MateTM reagent (GenePharma, China). After 4–6 h of culture, the cells were replated, cultured for additional 48–72 h, and then used for experiments.
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2

RAGE siRNA Transfection Protocol

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RAGE siRNA (Shanghai GenePharma Co., Ltd., Shanghai, China) was transfected into the cells using X-tremeGENE siRNA (Roche Applied Science) according to the manufacturer’s protocol.
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