C57BL/6 mice were purchased from Charles River laboratories. TLR2-deficient, TLR4-deficient, Card9-deficient, MyD88-deficient, Dectin-1-deficient, FcRγ-deficient, μMT-deficient mice each on the isogenic C57BL/6 background were purchased from The Jackson Laboratory. All mice were housed under specific pathogen-free conditions, and used between 8 and 12 weeks of age. All experiments were performed using sex- and age-matched controls under Cincinnati Children’s Hospital Research Foundation IACUC approved protocols.
Myd88 deficient
Manufactured by Jackson ImmunoResearch
MyD88-deficient is a genetically engineered mouse model that lacks the MyD88 gene, which is a key adaptor protein in the Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) signaling pathways. This model is commonly used in immunological research to study the role of MyD88-dependent signaling in various biological processes.
Automatically generated - may contain errors
Lab products found in correlation
Tlr2 deficient, by Jackson ImmunoResearch (2 mentions)
Tlr4 deficient, by Jackson ImmunoResearch (2 mentions)
Card9 deficient, by Jackson ImmunoResearch (2 mentions)
Dectin 1 deficient, by Jackson ImmunoResearch (2 mentions)
Fcrγ deficient, by Jackson ImmunoResearch (2 mentions)
μmt deficient mice, by Jackson ImmunoResearch (2 mentions)
C57bl 6, by Jackson ImmunoResearch (2 mentions)
C57bl 6 mice, by Charles River Laboratories (2 mentions)
2 protocols using myd88 deficient
1
Genetic Knockout Mouse Strains
2
Genetic Knockout Mouse Strains
Check if the same lab product or an alternative is used in the 5 most similar protocols
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C57BL/6 mice were purchased from Charles River laboratories. TLR2-deficient, TLR4-deficient, Card9-deficient, MyD88-deficient, Dectin-1-deficient, FcRγ-deficient, μMT-deficient mice each on the isogenic C57BL/6 background were purchased from The Jackson Laboratory. All mice were housed under specific pathogen-free conditions, and used between 8 and 12 weeks of age. All experiments were performed using sex- and age-matched controls under Cincinnati Children’s Hospital Research Foundation IACUC approved protocols.
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