The cocaine·HCl standard was purchased from Lipomed (Arlesheim, Switzerland). Standards of phenacetin, diltiazem, lidocaine, procaine, hydroxyzine, benzocaine, paracetamol and myo-inositol were purchased from Sigma-Aldrich (Diegem, Belgium). Standards of benzoic acid and levamisole were purchased from Acros Organics (Geel, Belgium). Standards of caffeine, boric acid, glucose, maltose and starch were purchased from VWR Chemicals (Leuven, Belgium) and a standard of d -sorbitol was purchased from Merck Chemicals KGaA (Overijse, Belgium). Authentic cocaine street samples were obtained from the National Institute for Criminalistics and Criminology (Brussels, Belgium). Gelatine gel B was supplied by PB gelatins (United Kingdom). Carbon ItalSens IS-C Screen Printed Electrodes (SPE) were purchased from PalmSens (Utrecht, The Netherlands) and were used during all electrochemical measurements. The electrode surface area is 7.07 mm2. All laboratorium-based electrochemical measurements were performed using a Metrohm μAutolab III Potentiostat and NOVA 1.11 software.
Hydroxyzine
Manufactured by Merck Group
Sourced in Belgium, United States, United Kingdom
Hydroxyzine is a laboratory equipment product manufactured by Merck Group. It is a chemical compound used in research and analytical applications. The core function of Hydroxyzine is to serve as a chemical reagent for various experiments and analyses.
Automatically generated - may contain errors
Lab products found in correlation
Benzocaine, by Merck Group (1 mentions)
Levamisole, by Thermo Fisher Scientific (1 mentions)
Paracetamol, by Merck Group (1 mentions)
Myo inositol, by Merck Group (1 mentions)
Lidocaine, by Merck Group (1 mentions)
Carbon italsens is c screen printed electrodes, by PalmSens (1 mentions)
Boric acid, by Avantor (1 mentions)
Phenacetin, by Merck Group (1 mentions)
Procaine, by Merck Group (1 mentions)
Diltiazem, by Merck Group (1 mentions)
Maltose, by Avantor (1 mentions)
Mitotempo, by Merck Group (1 mentions)
Bcl2 associated x (bax), by Cell Signaling Technology (1 mentions)
P jak2, by Cell Signaling Technology (1 mentions)
Cyclin d1, by Cell Signaling Technology (1 mentions)
Primary antibodies against cleaved caspase 3, by Cell Signaling Technology (1 mentions)
P jak1, by Santa Cruz Biotechnology (1 mentions)
Stat2, by Cell Signaling Technology (1 mentions)
Antibodies against bcl 2, by Santa Cruz Biotechnology (1 mentions)
P stat1, by Cell Signaling Technology (1 mentions)
3 protocols using hydroxyzine
1
Electrochemical Analysis of Cocaine in Street Samples
2
Molecular Mechanism of Hydroxyzine, Mito-TEMPO, and NAC
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Hydroxyzine, Mito-TEMPO, and N-acetyl cysteine (NAC) were obtained from Sigma Aldrich (St. Louis, MO, USA). Primary antibodies against cleaved caspase-3, cleaved caspase-7, cleaved caspase-8, cleaved caspase-9, cleaved PARP, Bax, Bak, SOD1, cyclin D1, CDK2, STAT1, p-STAT1, STAT2, p-STAT3 (Ser727), p-STAT3 (Tyr705), JAK2, p-JAK2, Akt, p-Akt, ERK, p-ERK, JNK, p-JNK, p38, p-p38, HSP90, and c-Src were purchased from Cell Signaling Technology (Denver, CO, USA). Antibodies against Bcl-2, Bcl-xL, SOD2, cyclin A, cyclin D2, cyclin D3, cyclin E, p16, p21, p27, p53, p-JAK1, and MDM2 were obtained from Santa Cruz Biotechnology (Dallas, TX, USA). Also, anti-survivin antibody was purchased from Novus Biologicals (Centennial, CO, USA), and anti-beta-actin antibody was from Sigma Aldrich (Burlington, MA, USA). Anti-catalase and anti-cyclin B antibodies were obtained from Abcam (Cambridge, UK), and anti-JAK1 antibody was from Millipore (Burlington, MA, USA). All the horse-radish peroxidase (HRP)-conjugated secondary antibodies specific to mouse or rabbit antibody were purchased from Thermo Fisher Scientific (Waltham, MA, USA).
3
Sensitive Quantification of Antihistamines
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Ultrapure water was purified by a Triple Red ultrapure water system (Triple Red Ltd., Buckinghamshire, UK). Acetonitrile, chloroform, ethyl acetate, hexane, hydrochloric acid, methanol, sodium hydroxide and Methyl tert-butyl ether (TBME) were purchased from Fisher Scientific UK Ltd. (Loughborough, UK). Optima grade formic acid was purchased from LGC Ltd (Middlesex, UK).
Hydroxyzine was purchased from Sigma Aldrich (Dorset, UK), Hydroxyzine-d8 was from Lipomed (Switzerland; Kinesis/UK), Cetirizine was from Pfizer Ltd (Tadworth, UK) and Cetirizine-d8 was purchased from Toronto Research Chemicals (Canada).
Hydroxyzine was purchased from Sigma Aldrich (Dorset, UK), Hydroxyzine-d8 was from Lipomed (Switzerland; Kinesis/UK), Cetirizine was from Pfizer Ltd (Tadworth, UK) and Cetirizine-d8 was purchased from Toronto Research Chemicals (Canada).
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