Sensitivity encoding head coil

Twenty-three patients (12 NFV, 11 SV) and 24 controls received a high resolution T1-weighted structural MRI. All controls and 13 patients were scanned on a 3T Philips Intera system equipped with an 8-channel receive-only head coil (SENSitivity Encoding head coil). Ten patients were scanned on a 3T Philips Achieva dstream scanner equipped with a 32-channel head volume coil. An identical 3D turbo field echo sequence was used on both systems (coronal inversion recovery prepared 3D gradient-echo images, inversion time (TI) 900 ms, shot interval = 3,000 ms, echo time (TE) = 4.6 ms, flip angle 8°, 182 slices, voxel size 0.98 × 0.98 × 1.2 mm³). The diffusion weighted images consisted of 45 directions of diffusion weighting with b = 800 as well as 1 non-diffusion weighted image (B0), acquired in the axial plane, with isotropic voxel size of 2.2 mm, TR 9,900 ms, TE 90 ms, flip angle 90°, fold over direction AP, fat shift direction A (anterior), in-plane parallel image acceleration (SENSE) factor 2.5.

A group of 54 healthy elderly participants (age (mean std): 65.2 5.6 yrs; 31 male) [40] (link) performed an associative-semantic judgement task. Twenty-eight subjects were scanned on a 3T Philips Intera system equipped with an 8-channel receive-only head coil (Philips SENSitivity Encoding head coil). Twenty-six subjects could not undergo the fMRI in the Intera system due to space limitation in the scanner lumen in combination with the screen. These subjects were scanned on a 3T Philips Achieva system equipped with a 32-channel receive-only head coil (Philips 10 SENSitivity Encoding head coil) which used a screen placed behind the individual's head for the projection.
The protocol was approved by the Ethics Committee University Hospitals Leuven (EudraCT: 2009-014475-45) and written informed consent was obtained from all subjects in accordance with the Declaration of Helsinki.

All patients, except Case 10 (claustrophobia), and 86 healthy controls received a high resolution T₁-weighted structural MRI on a 3 T Philips Intera system equipped with an 8-channel receive-only head coil (Philips SENSitivity Encoding head coil), using a 3D turbo field echo sequence. Further details are provided in the Supplementary material.