Ultrapro

Manufactured by Johnson & Johnson

Sourced in United States, Germany

Ultrapro is a laboratory equipment product by Johnson & Johnson. It is designed for conducting various scientific experiments and analyses. The core function of Ultrapro is to provide a reliable and accurate platform for laboratory work.

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Lab products found in correlation

Vypro, by Johnson & Johnson (2 mentions) Prolene 2 0, by Johnson & Johnson (2 mentions) Histoacryl, by B. Braun (1 mentions) Spss 26.0 statistical, by IBM (1 mentions) Sulbactam, by Pfizer (1 mentions) Prolene, by Johnson & Johnson (1 mentions) Securestrap, by Johnson & Johnson (1 mentions)

Close spelling variants of this product

Ultrapro® mesh (2 citations)

7 protocols using ultrapro

Tension-Free Hernioplasty Techniques

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The procedures were performed under local anaesthesia as ambulatory surgery. In cases of bilateral hernias (n = 4), each side was treated individually; the second operation began when the first was finished.
The tension-free hernioplasty was performed by using a 9 × 13 cm trimmed lightweight polypropylene mesh (Optilene® mesh 60 g/m², B. Braun, Germany), partly absorbable self-gripping polyester/polylactic mesh (ParietexProGrip®, 14 × 9 cm, 38 g/m², Covidien, USA) or partly absorbable poliglecaprone-25/polypropylene mesh (Ultrapro®, 7.6 × 15 cm, 28 g/m², Ethicon, USA). The fixation of the mesh was done either by a 0.5 ml of butyl-2-cyanoacrylate tissue glue (Histoacryl®, B. Braun, Germany), with a self-fixing mesh (ParietexProgrip®, Covidien, USA) or non-absorbable suture fixation (2-0 Prolene®, Ethicon, USA), as described earlier (8).

Matikainen M., Vironen J., Kössi J., Hulmi T., Hertsi M., Rantanen T, & Paajanen H. (2020). Impact of Mesh and Fixation on Chronic Inguinal Pain in Lichtenstein Hernia Repair: 5-Year Outcomes from the Finn Mesh Study. World Journal of Surgery, 45(2), 459-464.

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Endoscopic Hernia Repair for Groin Pain

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Physical examination was performed by a sports medicine physician and a surgeon, both experienced in groin pathology, according to the guidelines proposed by Hölmich et al. [22 (link)].
Additional imaging (ultrasound, X-ray of the pelvis/hips and SPECT-CT scan) was performed to rule out other pathology causative of groin pain.
Surgical treatment consisted of endoscopic totally extraperitoneal (TEP) hernia repair. Surgery was performed under general anesthesia. A 10 x 15 cm lightweight polypropylene mesh (Ultrapro, Ethicon, a Johnson & Johnson company, Amersfoort, The Netherlands) was placed in a tension free manner without fixation. All operations were performed by two surgeons with extensive experience in endoscopic hernia surgery. Intra-operative findings were recorded. In case of a true inguinal hernia, classification according to Nyhus [23 (link)] was used. All patients were discharged from the hospital within 24 hours from surgery.
Patients were advised to take paracetamol in combination with non-steroidal anti-inflammatory drugs (NSAID’s) for the first postoperative days for pain management. No restrictions were given except for no strenuous activities in the first week postoperatively. Early return to sport was promoted. A (care as usual) rehabilitation program under supervision of their physiotherapist was advised.

Brans E., Reininga I.H., Balink H., Munzebrock A.V., Bessem B, & de Graaf J.S. (2019). Early recovery after endoscopic totally extraperitoneal (TEP) hernia repair in athletes with inguinal disruption: A prospective cohort study. PLoS ONE, 14(12), e0226011.

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Polypropylene Mesh Classification and Laparoscopic Repair

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The SHR classifies polypropylene-based flat meshes by weight, arbitrarily as standard (50 g/m² or greater) or lightweight (less than 50 g/m²), but disregards pore size.^{31 (link)} Accordingly, pure polypropylene meshes are either StdPPM or lightweight pure polypropylene mesh (LWPPM).
SHR further registers 3 lightweight composite polypropylene-based mesh options for laparoscopic repair by their brand names, Vypro and Ultrapro (Ethicon), and Timesh (PFM Medical). The SHR has not distinguished various generations and versions of these 3 trademarks.
Because polyester meshes are not classified by weight in SHR, they were included only in the first stage of the analyses.
The final study stage comprised solely polypropylene-based meshes, dichotomously classified as StdPPM or LWM.

Novik B., Sandblom G., Ansorge C, & Thorell A. (2022). Association of Mesh and Fixation Options with Reoperation Risk after Laparoscopic Groin Hernia Surgery: A Swedish Hernia Registry Study of 25,190 Totally Extraperitoneal and Transabdominal Preperitoneal Repairs. Journal of the American College of Surgeons, 234(3), 311-325.

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Vaginal Contractility Assessment Protocol

Cited 1 time

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Sample sizes were calculated using previously published data in which the contractile function of the nonhuman primate vagina following the implantation of Restorelle and UltraPro (Ethicon, Somerville, NJ, USA) was compared to Sham [17 (link)]. Based on that data, eight animals per group would be needed to detect differences between Sham, PP, and PDMS in the contractile function (primary endpoint) with a power of 85% using a one-way ANOVA with a two-sided significance level of 0.05. Kolmogorov-Smirnov tests were utilized to assess the normality of the data. Normally distributed data is represented as mean ± standard deviation and non-normally distributed data is represented as median (interquartile range). One-way ANOVA with Gabriel’s post-hoc testing was utilized to compare the contractile response to 120 mM KCl, total collagen content, and sGAG between groups while smooth muscle thickness was compared between groups using Kruskal-Wallis tests followed by Mann-Whitney tests with a Bonferroni correction when appropriate. Mann-Whitney tests were used to compare the percent of red, orange, yellow, and green fibers and the red to green ratio. All statistical analyses were performed using SPSS 26.0 statistical software (IBM, Armonk, NY, USA).

Knight K.M., King G.E., Palcsey S.L., Artsen A.M., Abramowitch S.D, & Moalli P.A. (2021). A soft elastomer alternative to polypropylene for pelvic organ prolapse repair: a preliminary study. International urogynecology journal, 33(2), 327-335.

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Open Sublay Hernia Repair Technique

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For open sublay hernia repair, the skin incision was made above the hernia, and the hernia sack was mobilized. After repositioning of the hernia, the rectus sheet was opened on both sides, and the posterior layer of the rectus sheet was dissected away from the rectus abdominis muscle. The dissection was extended laterally to the linea semilunaris to facilitate a mesh overlap of at least 5 cm to each site. Next, the posterior layer of the rectus sheet was closed by a running suture (Prolene™ 2–0, Ethicon GmbH, Norderstedt, Germany). The mesh (Ultrapro®, Ethicon GmbH, Norderstedt, Germany) was placed in a retromuscular position and fixed with sutures (Prolene™ 2–0, Ethicon GmbH, Norderstedt, Germany). Following this, wound drainage was positioned above the mesh to the surgeon’s discretion, and the anterior layer of the rectus sheet was closed by a running suture (Prolene™ 2–0, Ethicon GmbH, Norderstedt, Germany).

Plitzko G.A., Stüben B.O., Giannou A., Reeh M., Izbicki J.R., Melling N, & Tachezy M. (2023). Robotic-assisted repair of incisional hernia—early experiences of a university robotic hernia program and comparison with open and minimally invasive sublay technique (eMILOS). Langenbeck's Archives of Surgery, 408(1), 396.

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Comparison of Polypropylene Mesh Characteristics

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Two different monofilament polypropylene meshes were investigated in this study. Ultrapro^® (Ethicon Inc., Somerville, NJ, USA) is a large-pore polypropylene mesh with additional absorbable poliglecaprone. The absorption of the poliglecaprone component takes up to 120 days. Premilene^® (Atrium Medical, Mijdrecht, The Netherlands) is a small-pore, polypropylene mesh. Detailed characteristics of both meshes are summarized in Table 1.Table 1

Characteristics of mesh material used for incisional hernia repair in this trial

	Ultrapro^®	Premilene^®
Material	Polypropylene & Poliglecaprone (resorption within 120 days)	Polypropylene
Weight	28 g/m²	82 g/m²
Thickness	0.5 mm	0.5 mm
Pore size	3–4 mm	0.8 mm
Filament thickness	0.1 mm	0.15 mm
Tensile strength	35 N/cm (polypropylene)	101 N/cm

Kroh A., Zufacher M., Eickhoff R., Heise D., Helmedag M., Ulmer F., Neumann U.P., Conze J., Hilgers R.D, & Binnebösel M. (2023). No difference in outcomes between large- and small-pore meshes in a prospective, randomized, multicenter trial investigating open retromuscular meshplasty for incisional hernia repair. Langenbeck's Archives of Surgery, 408(1), 22.

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Hernia Repair Techniques and Mesh Types

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Inguinal/femoral hernias were repaired either by open (Lichtenstein) or minimally invasive techniques, that is totally extraperitoneal (TEP) or transabdominal preperitoneal (TAPP). Preoperatively, 2 g ampicillin/1 g sulbactam (Pfizer, Berlin, Germany) was given for Lichtenstein, but not for minimally invasive repair. Partially absorbable lightweight polypropylene-polyglecaprone mesh (ULTRAPRO, Ethicon, Norderstedt, Germany) was cropped to 15 × 12 cm for augmentation.
Same antibiotic was pre-operatively given for ventral, incisional and parastomal hernia repairs. Between 2001 and 2012, we implanted lightweight polypropylene-polyglactin mesh (Vypro, Ethicon, Norderstedt, Germany) during open repair. Afterwards, we switched to a lightweight polypropylene mesh (Optilene, Braun, Melsungen, Germany). The meshes were routinely positioned retromuscularly with minimum 5 cm overlap of the fascial defect and fixed with interrupted 2/0 polypropylene sutures (Prolene, Ethicon, Norderstedt, Germany). During minimally invasive intraperitoneal onlay mesh (IPOM), a non-absorbable polypropylene mesh (Proceed, Ethicon, Norderstedt, Germany) was fixed with four 2/0 polypropylene sutures (Prolene, Ethicon, Norderstedt, Germany) and absorbable tacks (Securestrap, Ethicon, Norderstedt, Germany) in double crown technique.

Lee L.D., Stroux A., Nickisch D., Wröbel L., Aschenbrenner K., Weixler B., Kreis M.E, & Lauscher J.C. (2020). Operative outcome of hernia repair with synthetic mesh in immunocompromised patients. ANZ journal of surgery, 90(11).

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