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Pioglitazone hydrochloride

Manufactured by Fujifilm
Sourced in Japan

Pioglitazone hydrochloride is a chemical compound used in laboratory settings. It is a pharmaceutical ingredient used in the development and testing of various medical products. The primary function of pioglitazone hydrochloride is to serve as a research tool for scientists and researchers working in the healthcare and pharmaceutical industries.

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2 protocols using pioglitazone hydrochloride

1

Cell Culture Reagents and Compounds

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All cell culture plasticware was purchased from Becton, Dickinson and Company (NJ, USA). Pioglitazone hydrochloride, rosiglitazone, glimepiride, GW9662, and dimethyl sulfoxide (DMSO) were obtained from Wako Pure Chemical Industries Ltd. (Osaka, Japan). Metformin (1,1-dimethyl biguanide hydrochloride) was purchased from Sigma Aldrich (MO, USA).
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2

Lipid Source and Pioglitazone Effects

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All diets comprised 60 energy% (en%) carbohydrates, 20 en% fats, and 20 en% protein (Supplementary Table 1). The safflower oil diet included 20 en% safflower oil (Benibana Foods Co., Ltd., Tokyo, Japan) as a lipid source, and the fish oil diet was prepared with 10 en% safflower oil and 10 en% fish oil (NOF Co., Tokyo, Japan). These diets were designated the SO and FO diets, respectively. The SO and FO diets were each supplemented with 0.012 weight% pioglitazone hydrochloride (Wako Pure Chemical Industries, Ltd., Osaka, Japan) and were designated the SP and FP diets, respectively. These experimental diets, which were supplemented with t-butyl hydroquinone (Wako Pure Chemical Industries) to prevent fatty acid oxidation, were stored at -30°C.
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