Psn version 5

Manufactured by ICON Development Solutions

Sourced in United States

PsN version 5.0.0 is a software application designed for pharmacometric modeling and simulation. It provides tools for population analysis, data management, and simulation. The software is used for the analysis of pharmacokinetic and pharmacodynamic data.

Automatically generated - may contain errors

Lab products found in correlation

Nonmem version 7, by ICON Development Solutions (2 mentions) R statistical software version 4, by R Project for Statistical Computing (1 mentions)

2 protocols using psn version 5

Pharmacokinetic Modeling of Rifampicin

Check if the same lab product or an alternative is used in the 5 most similar protocols

For simulation of rifampicin plasma concentrations, NONMEM version 7.3.0 (Icon Development Solutions, Hanover, MD, USA) [37 ] assisted by PsN version 5.0.0 (Department of Pharmacy, Uppsala University, Uppsala, Sweden) [43 (link)] was used. Dataset manipulation, data visualization and ML model training was performed in R statistical software version 4.0.3 (R Foundation for Statistical Computing, Vienna, Austria) [69 ]. The computations were performed on resources provided by the Swedish National Infrastructure for Computing (SNIC) through Uppsala Multidisciplinary Center for Advanced Computational Science (UPPMAX).

Keutzer L., You H., Farnoud A., Nyberg J., Wicha S.G., Maher-Edwards G., Vlasakakis G., Moghaddam G.K., Svensson E.M., Menden M.P, & Simonsson U.S. (2022). Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin. Pharmaceutics, 14(8), 1530.

+ Open protocol

+ Expand

Nonlinear Mixed-Effects Modeling in R

Check if the same lab product or an alternative is used in the 5 most similar protocols

All simulations were performed in NONMEM version 7.3.0 (Icon Development Solutions, Hanover, MD, USA)²⁴ assisted by PsN version 5.0.0 (Department of Pharmacy, Uppsala University, Uppsala, Sweden).²⁵ Dataset creation and creation of graphs were performed in R statistical software version 4.1.1.²⁶

Keutzer L., Akhondipour Salehabad Y., Davies Forsman L, & Simonsson U.S. (2022). A modeling‐based proposal for safe and efficacious reintroduction of bedaquiline after dose interruption: A population pharmacokinetics study. CPT: Pharmacometrics & Systems Pharmacology, 11(5), 628-639.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!