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Spss statistics for windows software version 22

Manufactured by IBM
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SPSS Statistics for Windows software version 22.0 is a statistical analysis software package. It provides tools for data management, analysis, and presentation. The software is designed to handle a wide range of data types and can be used for various statistical techniques, including regression analysis, correlation, and hypothesis testing.

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38 protocols using spss statistics for windows software version 22

1

Cardiometabolic Risk Factors Analysis

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The characteristics of the participants were described as the mean ± standard deviation (SD) or percentages. The online database was analyzed using SPSS Statistics software for Windows version 22.0 (IBM, Spain). Parametric or nonparametric statistics were applied depending on the goodness-of-fit for normal distribution as determined by the Shapiro–Wilk test and the equality of variances among groups as determined by Levene’s test. In addition, the effect of the variables analyzed on the cardiometabolic risk factors was assessed using Spearman’s rank test for correlations. Parametric quantitative data were analyzed by t-test. Analysis of nonparametric quantitative data was performed with Mann–Whitney’s U test. The statistical significance threshold was p < 0.05.
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2

Comparative Analysis of Uveitis Characteristics

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Data were presented as the mean ± standard deviation, unless otherwise indicated. Baseline characteristics included age, sex, refractive error, number of cells, degrees of vitreous haze, CMT, and MV. For comparison, data from the right eye of each patient was used if the uveitis severity was equivalent between both eyes. If the severity of uveitis was different, the clinical data from the eye with more severe uveitis was used for the comparison. IBM SPSS Statistics software for Windows, version 22.0 (IBM Corporation, Somers, NY, USA) was used for statistical analyses. For comparison among the multiple groups, Kruskal Wallis test was used for continuous variables and the chi square test was used for the analyses of categorical variables. For comparison between two groups according to the posterior involvement, the Student’s t-test was used for the analyses of continuous variables and the chi square test was used for the analyses of categorical variables. The comparison of CMT and MV after treatment for posterior uveitis or panuveitis, repeated measured analysis of variance (ANOVA) was used. Stepwise multiple regression analyses were performed to determine the associations of baseline factors with the mean CMT and the mean MV, respectively. Results with P < 0.05 were considered statistically significant.
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3

Statistical Analysis of mRNA Levels

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Statistical analyses were done using IBM SPSS Statistics software for Windows Version 22.0 (IBM®, Armonk, NY, USA). According the mRNAs levels distribution, the Student t-test or Mann Whitney U test were used in order to evaluate any statistical differences in the normalized expression of the mRNAs. The quality of the housekeeping genes was tested using the BestKeeper software [49 (link)]. Both endogenous controls presented a stable behavior, so both were used to normalize the mRNAs levels. The Kaplen Meier method and Log Rank test were used to establish the association of the TIMP-1 derived EV mRNA levels (low versus high) to the overall survival. The TIMP-1 derived EV mRNA levels low versus high levels were defined using the mean value of the –ΔCq.
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4

Age, Gender, and Tumor Impact on Recurrence

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To analyze the effects of age, gender, tumor size, and treatment modality on recurrence in the non-operative group, we used logistic regression analysis because the dependent variable was discrete (i.e., recurrence vs no-recurrence).
The data were collated in MS Excel and analyzed using SPSS Statistics Software for Windows version 22.0 (IBM Corp., Armonk, NY). Results are presented as means ± SDs, and statistical significance was accepted for P values of < .05.
The statistical validity of this study was certified, reviewed, and proofread by statisticians in the department of statistics at a national university.
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5

Preoperative Kidney Function Assessment in MDCM

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Kidney volumes, MDCM and serum creatinine levels are presented as the median with interquartile range, and blood pressure, and antihypertensive drugs are presented as the mean ± standard deviation. The preoperative and postoperative results were compared by the Wilcoxon signed rank test, or paired Student’s t test. The correlations between the ratio of MDCM and other factors were analyzed by Pearson correlation analysis. In addition, stepwise multifactor linear regression model was used. The patients were divided into two subgroups depending on the preoperative MDCM. The cutoff value was the median of MDCM. Subgroup A included patients with relatively low preoperative MDCM, and Subgroup B included patients with relatively high preoperative MDCM. The kidney volumes, MDCM, serum creatinine levels, blood pressure, and antihypertensive drugs of different subgroups were compared by the Wilcoxon rank sum test or Student’s t test. A p-value less than 0.05 was considered statistically significant. A specialist in medical statistics participated in all statistical analyses. All analyses were conducted using IBM SPSS Statistics software for Windows, version 22.0 (Armonk, NY, USA).
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6

Statistical Analysis of Experimental Data

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Data were analyzed statistically using IBM SPSS Statistics software for Windows, version 22.0 (IBM Corp., USA). The differences between the experimental groups in single-day parameters were determined using the nonparametric Mann–Whitney U test. Spearman's correlation test was used to analyze the association between different parameters assessed in the study. Probabilities of P < 0.05 were considered significant.
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7

Predictors of Recurrent Central Serous Chorioretinopathy

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The data are presented as mean ± standard deviation (range). Baseline characteristics included age, sex, refractive error, BCVA, and chronicity of CSC at the time of the initial visit. The mean SFCT, the greatest height of the SRF, and various imaging characteristics, such as choroidal hyperpermeability, flat irregular PED, and serous PED, were also evaluated. IBM SPSS Statistics software for Windows, version 22.0 (IBM Corp., Somers, NY, USA) was used for statistical analyses. The Kruskal–Wallis test was used for continuous variables, and the chi-square test was used for categorical variables when the clinical characteristics were compared between eyes with and without recurrence. Repeated-measured analysis of variance was used to compare the mean BCVA, the mean SFCT, and the mean CMT during the follow-up period. To investigate the possible predictive factors for the recurrence of CSC after the IVBIs, binary regression analysis using the forward analysis method was used. Mauchly's test of sphericity and Kolmogorov–Smirnov analyses were used to confirm statistical validity. A P-value < 0.05 was considered significant.
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8

Statistical Analysis of Quantitative and Categorical Variables

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Statistical analysis was performed using the SPSS Statistics software for Windows, version 22.0 (IBM Corp., Armonk, NY, USA). Continuous quantitative variables were expressed as mean ± s.d., and categorical variables were expressed as frequency distribution, median, and interquartile range (IQR). Comparison of continuous variables was performed using the Student’s t test. Categorical variables were compared by the chi-square test, while differences in distributions of ordinal data from independent samples were tested with Mann–Whitney U and Goodman and Kruskal’s gamma tests. The level of significance was set at 0.05 (two-tailed).
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9

Aqueous Endothelin-1 Levels in Diabetic Retinopathy

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The data were presented as mean ± standard deviation (range) values. Baseline characteristics included age, sex, refractive error, and BCVA at the initial visit. Medical histories, including hypertension and end-stage renal disease, were obtained from the medical charts of the patients. IBM SPSS Statistics software for Windows, version 22.0 (IBM Corp., Somers, NY, USA) was used for the statistical analyses. For continuous variables, the Kruskal-Wallis test was used for comparisons among three groups, and Mann-Whitney U test was used for comparison between two groups. The chi-square test was used for categorical variables. Repeated-measures analysis of variance was used to compare values for mean BCVA, mean CMT, and mean aqueous ET-1 levels after intravitreal injections. Pearson’s correlation analysis was performed to evaluate for any significant correlations between aqueous ET-1 level with visual and anatomical outcomes in the patients with advanced DR after intravitreal injection. Multiple regression analysis by using stepwise approach was used to investigate the correlation between the baseline factors with the mean aqueous ET-1 level at baseline. Mauchly’s test of sphericity and Kolmogorov-Smirnov analyses were used to confirm statistical validity. A P value <0.05 was considered statistically significant.
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10

Occupational Exposure and Oxidative Stress

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Urinary 8-OHdG, metals, and creatinine levels were first natural log-transformed to normalize their distributions before the Student’s t-test or regression analysis was done. Student’s t and Chi-Square statistics were used to compare the personal covariates, which were the urinary 8-OHdG and metals of welders and office workers. The association among urinary metals, personal covariates, work experience, and oxidative damage biomarkers was assessed using multiple linear regression; moreover, to minimize the effect of residual confounding of sociodemographic factors, such as sex, age, and race/ethnicity, on urinary biomarkers, urinary creatinine was adjusted as an independent variable in the linear regression analysis [25 (link)]. The level for statistical significance was set to α = 0.05 in all tests. Statistical analysis was conducted using IBM SPSS statistics software for Windows version 22.0 (IBM Corp., Armonk, NY, USA).
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