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Icariin i1286

Manufactured by Merck Group
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Sourced in United States

Icariin (I1286) is a chemical compound extracted from the plant Epimedium, also known as Horny Goat Weed. It is a dietary supplement ingredient and a natural product used in laboratory research. Icariin has been studied for its potential effects, but its core function is not to be interpreted or extrapolated upon.

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Lab products found in correlation

Insulin 91077c, by Merck Group (2 mentions) As160, by Cell Signaling Technology (2 mentions) Glut4, by Cell Signaling Technology (2 mentions) Irs 1, by Cell Signaling Technology (2 mentions) Normal mouse igg sc 2025, by Santa Cruz Biotechnology (2 mentions) Phosphor as160 ser588, by Cell Signaling Technology (2 mentions) Phosphor irs 1 ser307, by Cell Signaling Technology (2 mentions) Anti il 6 mouse monoclonal antibody sc 57315, by Santa Cruz Biotechnology (2 mentions) Palmitic acid p5585, by Merck Group (2 mentions) Phosphor akt thr308, by Cell Signaling Technology (2 mentions) Phosphor jnk thr183 tyr185, by Cell Signaling Technology (2 mentions) Histone h3, by Cell Signaling Technology (2 mentions) Ire1α, by Cell Signaling Technology (2 mentions) Nf κb p65, by Cell Signaling Technology (2 mentions)

2 protocols using icariin i1286

1

Insulin Signaling Pathway Regulation

Check if the same lab product or an alternative is used in the 5 most similar protocols
Antibodies against TXNIP (#14715), Akt (#2920), phosphor-Akt (Thr308) (#4056), AS160 (#2670), phosphor-AS160 (Ser588) (#8730), PDK1 (#13037), GLUT4 (#2213), PERK (#3192), IRE1α (#3294), CHOP (#5554), ATF6 (#65880), Histone H3 (#9715), IRS-1 (#2382), phosphor-IRS-1 (Ser307), JNK (#9252), phosphor-JNK (Thr183/Tyr185) (#4668), NF-κB p65 (#4764), phosphor-NF-κB p65 (Ser536) (#3033), and IκBα (#9242) were from Cell Signaling TECHNOLOGY (Beverly, MA, United States). Anti-PERK (phosphor T982) (ab192591), STAT3 (ab119352), STAT3 (phosphor Y705) (ab76315), and SOCS3 (ab16030) antibodies were obtained from Abcam, Inc. (Cambridge, MA, United States). Anti-IL-6 mouse monoclonal antibody (sc-57315) and normal mouse IgG (sc-2025) were purchased from Santa Cruz Biotechnology (Shanghai) Co., Ltd. (Shanghai, China). Insulin (91077C), palmitic acid (P5585), and icariin (I1286) were acquired from Sigma-Aldrich, Corp. (St. Louis, MO, United States). 2-Deoxy-D-2-[3H] glucose was obtained from HTA, Co. Ltd. (Beijing, China).
Li M., Zhang Y., Cao Y., Zhang D., Liu L., Guo Y, & Wang C. (2018). Icariin Ameliorates Palmitate-Induced Insulin Resistance Through Reducing Thioredoxin-Interacting Protein (TXNIP) and Suppressing ER Stress in C2C12 Myotubes. Frontiers in Pharmacology, 9, 1180.
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2

Insulin Signaling Pathway Regulation

Check if the same lab product or an alternative is used in the 5 most similar protocols
Antibodies against TXNIP (#14715), Akt (#2920), phosphor-Akt (Thr308) (#4056), AS160 (#2670), phosphor-AS160 (Ser588) (#8730), PDK1 (#13037), GLUT4 (#2213), PERK (#3192), IRE1α (#3294), CHOP (#5554), ATF6 (#65880), Histone H3 (#9715), IRS-1 (#2382), phosphor-IRS-1 (Ser307), JNK (#9252), phosphor-JNK (Thr183/Tyr185) (#4668), NF-κB p65 (#4764), phosphor-NF-κB p65 (Ser536) (#3033), and IκBα (#9242) were from Cell Signaling TECHNOLOGY (Beverly, MA, United States). Anti-PERK (phosphor T982) (ab192591), STAT3 (ab119352), STAT3 (phosphor Y705) (ab76315), and SOCS3 (ab16030) antibodies were obtained from Abcam, Inc. (Cambridge, MA, United States). Anti-IL-6 mouse monoclonal antibody (sc-57315) and normal mouse IgG (sc-2025) were purchased from Santa Cruz Biotechnology (Shanghai) Co., Ltd. (Shanghai, China). Insulin (91077C), palmitic acid (P5585), and icariin (I1286) were acquired from Sigma-Aldrich, Corp. (St. Louis, MO, United States). 2-Deoxy-D-2-[3H] glucose was obtained from HTA, Co. Ltd. (Beijing, China).
Li M., Zhang Y., Cao Y., Zhang D., Liu L., Guo Y, & Wang C. (2018). Icariin Ameliorates Palmitate-Induced Insulin Resistance Through Reducing Thioredoxin-Interacting Protein (TXNIP) and Suppressing ER Stress in C2C12 Myotubes. Frontiers in Pharmacology, 9, 1180.
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