Drd2 egfp

Manufactured by Jackson ImmunoResearch

Sourced in Montenegro

Drd2-EGFP is a fluorescently labeled antibody that targets the dopamine D2 receptor (Drd2). It is designed for use in immunohistochemistry, flow cytometry, and other applications where the detection of Drd2-expressing cells is required.

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Lab products found in correlation

Drd1 tdtomato, by Jackson ImmunoResearch (1 mentions) Aldh1l1 cre, by Jackson ImmunoResearch (1 mentions) C57bl 6j, by Jackson ImmunoResearch (1 mentions)

2 protocols using drd2 egfp

Transgenic Mouse Lines for Neuroscience

Cited 1 time

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C57/Bl6, Drd1-EGFP, Drd2-EGFP, and α2-knockout mice (Glra2-KOs) of the age of 8–16 weeks were used in the study. Glra2-KOs were generated by deletion of the exon 7 of Glra2 (Avila et al., 2013b (link)). Drd1-EGFP and Drd2-EGFP (Gong et al., 2003 (link)) mouse lines were obtained from Jackson Laboratory. Glra2-KOs were fully back-crossed to C57/Bl6, and Drd1a-EGFP and Drd2-EGFP to CD1 background and genotyped as described previously (Gong et al., 2003 (link); Avila et al., 2013b (link)). C57/Bl6, Drd1-EGFP, and Drd2-EGFP mice of both sexes and Glra2-KO and WT males were used in the study.
All experimental procedures were performed according to the Institutional Animal Care Committee guidelines and were approved by local ethics committees. All efforts were made to minimize the suffering and number of animals used.

Molchanova S.M., Comhair J., Karadurmus D., Piccart E., Harvey R.J., Rigo J.M., Schiffmann S.N., Brône B, & Gall D. (2018). Tonically Active α2 Subunit-Containing Glycine Receptors Regulate the Excitability of Striatal Medium Spiny Neurons. Frontiers in Molecular Neuroscience, 10, 442.

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Transgenic Mouse Models for Neurological Research

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All experimental procedures were approved by the Mayo Clinic Institutional Animal Care and Use Committee and performed in accordance with NIH guidelines. Adenosine A2A receptor (A2AR: Adora2A, MMRRC:031168-UCD)-Cre mice were provided by Dr. Jiang-Fan Chen at Wenzhou Medical University. Aldehyde dehydrogenase 1 family, member L1 (ALDH1L1)-Cre (Stock #023748), Dopamine D2 receptor (D2R: DRD2)-eGFP (stock #030255), Dopamine D1 receptor (D1R: DRD1)-tdTomato (stock #016204) and C57BL/6J mice were purchased from Jackson Laboratory (Bar Harbor, ME). The ENT1 KO mice were generated as described (27 (link)). Mice were housed in standard Plexiglas cages and the colony room was maintained at a constant temperature (24 ± 1°C) and humidity (60 ± 2%) with a 12 h light/dark cycle (lights on at 07:00 A.M.). We used 8- to 10-wk-old male mice for all experiments.

Kang S., Hong S.I., Lee J., Peyton L., Baker M., Choi S., Kim H., Chang S.Y, & Choi D.S. (2020). Activation of Astrocytes in the Dorsomedial Striatum Facilitates Transition from Habitual to Goal-Directed Reward-Seeking Behavior. Biological psychiatry, 88(10), 797-808.

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