Choline dihydrogencitrate

Manufactured by Merck Group

Choline dihydrogencitrate is a chemical compound that is a salt of choline and citric acid. It is a white crystalline powder that is soluble in water. Choline dihydrogencitrate is used as a source of choline in various laboratory and research applications.

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Lab products found in correlation

Oxalic acid, by Honeywell (1 mentions) Malic acid, by Merck Group (1 mentions) Chitin from shrimp shells, by Merck Group (1 mentions) Citric acid monohydrate, by Merck Group (1 mentions) Choline chloride, by Merck Group (1 mentions) Potassium carbonate, by Merck Group (1 mentions) Betaine hydrochloride, by Merck Group (1 mentions) Lc ms grade ammonium acetate, by Thermo Fisher Scientific (1 mentions) Hydrochloric acid (hcl), by Merck Group (1 mentions)

Close spelling variants of this product

Choline

2 protocols using choline dihydrogencitrate

Chitin Extraction Using Deep Eutectic Solvents

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Four HBAs were used in this work, namely,
choline chloride ([Ch]Cl, ≥98% purity) and choline dihydrogen
citrate ([Ch]DHC, 99% purity) from Sigma-Aldrich, potassium bicarbonate
(99.7% purity) from Honeywell Fluka, and potassium carbonate (99%
purity) from Merck. Regarding the HBDs, glycerol (G, 98–101%
purity) acquired from Pharmachem Sušnik, ethylene glycol (EG,
≥99.5% purity) purchased from Fluka, acetic acid glacial (AA,
100% purity) supplied by Honeywell, and oxalic acid (OA, 98% purity),
malic acid (MA, 98% purity), and citric acid monohydrate (CA, 100.5%
purity) from Sigma-Aldrich were used. Sodium hydroxide (98% purity)
was obtained from Honeywell Fluka. Chitin from shrimp shells (practical
grade, powder) was acquired from Sigma-Aldrich.

Vicente F.A., Huš M., Likozar B, & Novak U. (2021). Chitin Deacetylation Using Deep Eutectic Solvents: Ab Initio-Supported Process Optimization. ACS Sustainable Chemistry & Engineering, 9(10), 3874-3886.

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Quantitative Determination of Metabolites

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All glassware was acid-rinsed before use with 10% hydrochloric acid (purchased from Sigma Aldrich) followed by MilliQ water. Betaine hydrochloride and choline dihydrogen citrate were purchased from Sigma Aldrich. Trimethylamine N-Oxide.2H2O was obtained from Fluka.
Deuterated GBT (d11-GBT), used as an internal standard (ISTD), was sourced from Cambridge Isotope Laboratories Inc.. Methanol (LC/MS grade), chloroform (HPLC grade), Acetonitrile (HPLC grade), formic acid (LC/MS additive) and ammonium acetate (LC/MS grade) were purchased from Fisher Scientific.

Beale R, & Airs R. (2016). Quantification of glycine betaine, choline and trimethylamine N-oxide in seawater particulates: Minimisation of seawater associated ion suppression. Analytica chimica acta, 938.

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