18F-FDG is produced by a MiniTrace Cyclotron and automatic synthesis system by GE Healthcare, with a radiochemical purity of more than 95%. Patients fasted for at least six hours before the examination and had blood glucose lower than 10 mmol/L. The intravenous injection of FDG ranged from 4.44 MBq/kg to 5.55 MBq/kg. Thirty-eight patients were given oral sedation for PET scans. PET/CT scans were performed 60 minutes after injecting radiolabeled 18F-FDG using a Siemens PET/CT system (Horizon). The examination included a head-to-toe CT scan (80 kV; 50-100 mAs) and a three-dimensional (3D) PET scan (2 mins per bed; 6-7 beds). The rotation time was 0.6. The slice thickness was 3.75 mm. The increment was 3.27. The pitch was 0.984. The images were displayed on the Syngo.via workstation.
Minitrace cyclotron
Manufactured by GE Healthcare
Sourced in United States
The Minitrace cyclotron is a compact particle accelerator used for the production of radioactive isotopes. It generates high-energy protons that are used to produce medical radioisotopes for diagnostic imaging and therapeutic applications. The Minitrace cyclotron is designed for on-site radioisotope production, providing a reliable and efficient source of these essential materials for healthcare facilities.
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Lab products found in correlation
Discovery 710, by GE Healthcare (1 mentions)
Discovery ste 16 slice pet ct scanner, by GE Healthcare (1 mentions)
Tracerlab fx fn synthesizer, by GE Healthcare (1 mentions)
Signa tof pet mr, by GE Healthcare (1 mentions)
Ge discovery st, by GE Healthcare (1 mentions)
Ge revolution 256, by GE Healthcare (1 mentions)
Definition as, by GE Healthcare (1 mentions)
7 protocols using minitrace cyclotron
1
Standardized 18F-FDG PET/CT Protocol
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18F-FDG is produced by a MiniTrace Cyclotron and automatic synthesis system by GE Healthcare, with a radiochemical purity of more than 95%. Patients fasted for at least six hours before the examination and had blood glucose lower than 10 mmol/L. The intravenous injection of FDG ranged from 4.44 MBq/kg to 5.55 MBq/kg. Thirty-eight patients were given oral sedation for PET scans. PET/CT scans were performed 60 minutes after injecting radiolabeled 18F-FDG using a Siemens PET/CT system (Horizon). The examination included a head-to-toe CT scan (80 kV; 50-100 mAs) and a three-dimensional (3D) PET scan (2 mins per bed; 6-7 beds). The rotation time was 0.6. The slice thickness was 3.75 mm. The increment was 3.27. The pitch was 0.984. The images were displayed on the Syngo.via workstation.
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18F-FDG is produced by a MiniTrace Cyclotron and automatic synthesis system by GE Healthcare, with a radiochemical purity of more than 95%. Patients fasted for at least six hours before the examination and had blood glucose lower than 10 mmol/L. The intravenous injection of FDG ranged from 4.44 MBq/kg to 5.55 MBq/kg. Thirty-eight patients were given oral sedation for PET scans. PET/CT scans were performed 60 minutes after injecting radiolabeled 18F-FDG using a Siemens PET/CT system (Horizon). The examination included a head-to-toe CT scan (80 kV; 50-100 mAs) and a three-dimensional (3D) PET scan (2 mins per bed; 6-7 beds). The rotation time was 0.6. The slice thickness was 3.75 mm. The increment was 3.27. The pitch was 0.984. The images were displayed on the Syngo.via workstation.
2
Standardized 18F-FDG-PET/CT Imaging Protocol
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18F-FDG-PET/CT imaging was obtained by a GE Discovery710 instrument, USA. 18F-FDG was produced by the GE Minitrace cyclotron and FDG synthesis module, and the radiochemical purity was > 95%. All patients fasted for more than 6 h, and blood glucose was controlled below 11.1 mmol/L before injection. Patients received an intravenous injection of approximately 3.70–5.55 MBq/Kg body weight of 18F-FDG, and PET/CT scans were performed from the top of the skull to the upper femur (limbs were scanned if necessary) after a 60 min rest. The CT scanning voltage was 120 keV, tube current was 100 mAs, and the layer thickness was 3.75 mm. PET scanning was performed with three-dimensional acquisition, 2.5 min/ bed, and 5 ~ 7 beds were collected. An iterative method was used to reconstruct the image.
3
Standardized FDG-PET/CT Protocol for Cancer Imaging
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18F-FDG is produced on a MiniTrace Cyclotron and automatic synthesis system of GE Healthcare, with a radiochemical purity of more than 95%. The patients fasted for at least 6 h before the examination and had blood glucose lower than 10 mmol/L. The intravenous injection of FDG ranged from 4.44 to 5.55 MBq/kg. Thirty-six patients were given oral sedation for PET scans. PET/CT scans were performed 60 minutes after injecting radiolabeled 18F-FDG using a Siemens PET/CT system (Horizon). The examinations included a head-to-toe CT scan (80 kV; 50–100 mAs) and a three-dimensional (3D) PET scan (2 min per bed; six to seven beds). The rotation time was 0.6. The slice thickness was 3.75 mm. The increment was 3.27. The pitch was 0.984. The images were displayed on the Syngo.via workstation.
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18F-FDG is produced on a MiniTrace Cyclotron and automatic synthesis system of GE Healthcare, with a radiochemical purity of more than 95%. The patients fasted for at least 6 h before the examination and had blood glucose lower than 10 mmol/L. The intravenous injection of FDG ranged from 4.44 to 5.55 MBq/kg. Thirty-six patients were given oral sedation for PET scans. PET/CT scans were performed 60 minutes after injecting radiolabeled 18F-FDG using a Siemens PET/CT system (Horizon). The examinations included a head-to-toe CT scan (80 kV; 50–100 mAs) and a three-dimensional (3D) PET scan (2 min per bed; six to seven beds). The rotation time was 0.6. The slice thickness was 3.75 mm. The increment was 3.27. The pitch was 0.984. The images were displayed on the Syngo.via workstation.
4
PET/CT Imaging Protocol for FDG Synthesis
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The PET/CT imaging was carried out on a Discovery STE 16-slice PET/CT scanner (GE Healthcare, USA) at the Tumor Hospital of Shanxi Province. 18F (fluorine-18) was produced by Minitrace cyclotron (GE, USA), and FDG (deoxidized fluoride glucose) kit was purchased from Jiangsu HuaYi Technology LTD (GE, USA). 18F-FDG (2-18F-fluoro-2-deoxy-d -glucose) was synthesized using a TRACERLAB FXN multifunctional synthesizer. The radiochemical purity was at least 90 %.
5
PET-CT Imaging of Brain Glucose Metabolism
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After 6-h fasting for reducing glucose uptake, patients underwent PET-CT examination and intravenous injection of 18F-FDG. Brain imaging was performed 30 min later, and the metabolic process and distribution situation of 18F-FDG were monitored in brain tissue; meanwhile, a CT Tomoscan scan was conducted for reconstructed images. Appearance of continuous high or low metabolic zones in two levels was considered as abnormal, and when the relative intensity of radioactivity was reduced or increased by 15% in bilateral corresponding zones, this was regarded as indicating a metabolic abnormality. The localization diagnosis for epileptic foci was performed in terms of brain function and imageology. The Discovery 16 CT and MINItrace Cyclotron produced by GE Corp. (USA) were used. 18F-FDG PET-CT was performed using a Tracerlab FXFN synthesizer from GE Medical Systems (USA), with a radiochemical purity of FDG >95%. According to scan plan, multilayer CT scanning was initially conducted with parameters as follows: voltage, 120 kV; electric current, 180 mA; 3D model reconstruction, FORE-interactive reconstruction; axial field-of-view (FOV), 25 cm; emission scanning acquisition, 25 min; thickness, 3.75 mm; matrix, 128×128; scanning range, entire head. A total of 40 cross-sectional images were obtained, and image fusion was performed through an Xeleris and AW4.3 workstation.
6
Simultaneous 18FDG-PET and MRI Brain Imaging
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All patients underwent 18FDG-PET and MRI brain imaging simultaneously in a hybrid PET/MR scanner (3.0 T, SIGNA TOF-PET/MR, GE Healthcare). The 18F-FDG was produced in our center by a Minitrace cyclotron (GE Healthcare, USA) and automatic synthesizer (PAT Biotechnology Company, Beijing, China). The radiochemical purity was > 95%.
All participants fasted for at least 6 h and stopped any drugs that could affect brain glucose metabolism for at least 12 h before the 18F-FDG injection. The intravenously injected dose was 0.1 mCi/kg (3.7 MBq/kg) after ensuring the blood glucose level was ≤ 200 mg/dL. The scan began 40 min post 18F-FDG injection, during which the subject rested in a quiet and dimly lit room. The total scanning time for PET was 15 min, and the 3D T1WI (three-dimensional gradient echo sequence, flip angle = 12°, time of echo [TE]/time of repetition [TR] = 2.6/6.9 ms, bandwidth = 50 KHz, FOV = 24 cm × 24 cm, matrix = 384 × 384) sequence was simultaneously acquired.
The PET data were reconstructed using the ordered subsets expectation maximum (OSEM) algorithm with TOF technique. The parameters were as follows: FOV = 30 cm × 30 cm, matrix = 192 × 192, filter cutoff = 3.0 mm, subsets = 28, iterations = 3. The PET attenuation correction was atlas-based MRI attenuation correction, combined with Dixon water-fat separation methods [27 (link)].
All participants fasted for at least 6 h and stopped any drugs that could affect brain glucose metabolism for at least 12 h before the 18F-FDG injection. The intravenously injected dose was 0.1 mCi/kg (3.7 MBq/kg) after ensuring the blood glucose level was ≤ 200 mg/dL. The scan began 40 min post 18F-FDG injection, during which the subject rested in a quiet and dimly lit room. The total scanning time for PET was 15 min, and the 3D T1WI (three-dimensional gradient echo sequence, flip angle = 12°, time of echo [TE]/time of repetition [TR] = 2.6/6.9 ms, bandwidth = 50 KHz, FOV = 24 cm × 24 cm, matrix = 384 × 384) sequence was simultaneously acquired.
The PET data were reconstructed using the ordered subsets expectation maximum (OSEM) algorithm with TOF technique. The parameters were as follows: FOV = 30 cm × 30 cm, matrix = 192 × 192, filter cutoff = 3.0 mm, subsets = 28, iterations = 3. The PET attenuation correction was atlas-based MRI attenuation correction, combined with Dixon water-fat separation methods [27 (link)].
7
Multimodal Imaging Protocol for Chest Diagnostics
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All the patients underwent unenhanced chest CT with a multidetector CT scanner (TOSHIBA Aquilion, Tokyo, Japan; SIEMENS Definition AS+, Munich, Germany; GE Revolution 256, GE HealthCare, Chicago, IL, USA; NMS NEuViz 128, Shenyang, China; GE Discovery ST). The CT protocol included the following parameters: tube voltage of 120 kVp, the field of view (FOV) of 320 mm by a matrix of 512×512 and the tube-current with automated modulation. Lung images were reconstructed with a slice thickness of 1.0 mm and were observed at both the lung window (level, −600 HU; width, 1,500 HU) and mediastinal window (level, 40 HU; width, 350 HU).
PET/CT imaging was performed using a GE Discovery ST-8 PET/CT scanner. 18F-FDG was produced and synthesized by the GE Mini Trace cyclotron via an automatic synthesis module, with a radiochemical purity of 95% or greater. Patients were fasted for a minimum of 6 hours before being injected 18F-FDG, at a dose of 3.70–5.55 MBq/kg. The whole body PET scans were acquired in 2-D mode and ranged from the head down to the root of the thigh. The obtained PET data were reconstructed using an ordered subset expectation maximization algorithm (6-bed positions; 3.5 minutes/bed; 128×128 matrix). All images were exported in DICOM format for feature extraction and further analysis.
PET/CT imaging was performed using a GE Discovery ST-8 PET/CT scanner. 18F-FDG was produced and synthesized by the GE Mini Trace cyclotron via an automatic synthesis module, with a radiochemical purity of 95% or greater. Patients were fasted for a minimum of 6 hours before being injected 18F-FDG, at a dose of 3.70–5.55 MBq/kg. The whole body PET scans were acquired in 2-D mode and ranged from the head down to the root of the thigh. The obtained PET data were reconstructed using an ordered subset expectation maximization algorithm (6-bed positions; 3.5 minutes/bed; 128×128 matrix). All images were exported in DICOM format for feature extraction and further analysis.
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