Vision scanner

MEG signals were recorded from 13 healthy adult subjects (mean age 29 ± 6 years, 5 females), already used in de Pasquale et al. (2016) (link). Subjects were asked to remain still in the MEG system while fixating a cross on a screen. We recorded 2 or 3 scans lasting 5 min from each subject. MEG signals were recorded using the 153-channel MEG system developed and installed at the University of Chieti (Della Penna et al., 2000 (link)). The system is placed within a four-layer magnetically shielded room allowing magnetometric recordings. Two EOG and two ECG channels were recorded simultaneously with the MEG signals, to be used for physiological artifact rejection. Neuro-magnetic and electrical signals were filtered in the band 0.16–250 Hz and were sampled at 1 kHz. Before and after each resting state run, the signal generated by five positioning coils placed on the subject’s head were recorded and used to co-register functional and anatomical data. Anatomical images were acquired using a 1.5 T Siemens Vision scanner, through a sagittal magnetization-prepared rapid acquisition gradient echo T1-weighted sequence (MP-RAGE) with repetition time (TR) = 9.7 s; echo time (TE) = 4 ms; α = 12°; inversion time = 1,200 ms; voxel size = 1 × 1 × 1.25 mm³.

PET/CT data acquisition was performed on a Siemens Biograph^TM mCT or Vision scanner according to the guidelines of the European Association of Nuclear Medicine (EANM; Varrone et al., 2009 (link)). The PET acquisition was started 30 min after injection of 200 MBq of ¹⁸F-FDG. The PET emission study (20 min, one-bed position) followed immediately the CT study used for attenuation correction. Ultra-law dose brain CT imaging was performed under standard conditions (120 kVp, 20 mAs, 128 × 0.6 collimation, a pitch of 1 and 1 s per rotation).

Structural and functional MRI was performed using a 3-T Siemens Vision scanner (gradient booster, standard head coil). Functional data were acquired using echo-planar imaging (whole brain coverage; 33 slices; 1 mm gap; voxel size: 3×3×3 mm; time to repeat (TR): 2 s). For the main experiment, 460 volumes were collected per session and participant. For the localizer, a total of 340 volumes were collected. Data can be made available upon request (Email: kriegstein@cbs.mpg.de).

PET/CT data acquisition was performed on a Siemens Biograph^TM mCT or Vision scanner according to the guidelines of the European Association of Nuclear Medicine (EANM) [64]. The PET acquisition was started approximately 30 min after injection of 200 MBq of 18F-FDG. The PET emission study (20 min, one-bed position) was conducted followed immediately by the CT study used for attenuation correction. Ultra-law dose brain CT imaging was performed under standard conditions (120 kVp, 20 mAs, 128 Å ~ 0.6 collimation, a pitch of 1 and 1 s per rotation).