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N butyllithium

Manufactured by Thermo Fisher Scientific
Sourced in China

N-butyllithium is a key organometallic reagent used in organic synthesis. It is a strong nucleophile and base that can be used in a variety of reactions, such as substitution, addition, and deprotonation. N-butyllithium is commonly employed in the synthesis of fine chemicals, pharmaceutical intermediates, and other specialty compounds.

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4 protocols using n butyllithium

1

Synthesis of Functional Organometallic Compounds

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All chemicals were used without further purification. 2-Chloro-5-methylthiophene (> 96.0%) was purchased from TCI Chemicals. Tributyl borate (98%) was purchased from Strem Chemicals. 1-Bromo-3,5-bis(trifluoromethyl)benzene (99%), n-butyllithium (1.6 M solution in hexanes, AcroSeal), zinc dust (98+%), and tetrahydrofuran (THF, 99.9%, extra dry, stabilized, anhydrous, SC, AcroSeal) were purchased from Acros Organics. Tetrakis(triphenylphosphine) palladium(0) (Pd(PPh3)4, 99%), glutaryl chloride (97%), TiCl4 (99.9% trace metals basis), sulfur powder (99.999%), 1-octadecence (ODE, tech. 90%), and oleylamine (OAm, tech. 70%) were purchased from Aldrich. Manganese acetate tetrahydrate (99%), sodium carbonate (99.8%), and all the solvents were purchased from Fisher Scientific Company. Ethyl 4-bromobenzoate (98+%), AlCl3 (anhydrous, 99.985%), cadmium acetate hydrate (99.999%), cadmium oxide (99.998%), zinc stearate (count as ZnO ≈ 14%), oleic acid (OLA, 90%) and selenium (200 mesh, 99.999%) were purchased from Alfa Aesar. Nitric acid (≥69.5%, TraceSELECT) was purchased from Fluka. 4-bromo-pyridine hydrochloride (98%) was purchased from Matrix Scientific. Cadmium myristate was self-made according to the literature method (Chen et al., 2008 (link)).
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2

Synthesis and Characterization of Metallic Nanoparticles

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All chemicals were purchased from Sigma-Aldrich unless otherwise noted. Tetrahydrofuran (THF) was dried over calcium hydride and potassium prior to use and DMEDA (Acros Organics) over calcium hydride. Ethanol (99.5%), n-heptane, acetic acid (99.9%), L-Selectride (1 M in THF), n-butyllithium (n-BuLi, 2.5 M in hexane), PMMA (M w = 35 kg mol -1 , Acros Organics), tetrachloroauric acid trihydrate (HAuCl 4 •3H 2 O, Alfa Aesar), silver trifluoroacetate (AgTFA), zinc acetate dihydrate, copper acetate, sodium hydroxide and lithium hydroxide monohydrate were used as received.
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3

Synthesis of Hybrid Polymer Composites

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(NH4)6Mo7O24·4H2O and CN2H4S were provided by Sinopharm Chemical Reagent Co., Ltd. n-Butyl lithium (2.5 M in hexane) was acquired from Alfa Aesar without further purification. Octavinyl-POSS was purchased from Hybrid-Plastics™. Dithioglycol (DITG) was obtained from Aladdin Industrial Corporation (Shanghai, China). Azobisisobutyronitrile (AIBN) was provided by Shanghai National Medicine Group Chemical Reagent Co., Ltd. Tetrahydrofuran (THF) and n-hexane were commercially available and of analytical grade.
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4

Fabrication of Cobalt-based Coordination Polymers

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Materials. The dichlorodimethylsilane (98%), trichloroethylene (>98%), hexachloro-1, 3butadiene (97%), n-butyllithium (1.6 M solution in hexanes) and N, N-dimethylformamide (DMF) were purchased from Alfa Aesar China (Tianjin, China). The cobalt nitrate hexahydrate (99.99 % metals basis) was bought from Macklin Co. (Shanghai, China) and 2-methylimidazole (99%) was purchased from TCI Co. (Shanghai, China). All other reagents were used as received.
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