The largest database of trusted experimental protocols

Chelerythrine

Manufactured by ChemFaces
Sourced in United States, China

Chelerythrine is a natural product isolated from various plant species, including the Chelidonium majus plant. It is a benzophenanthridine alkaloid with a distinctive chemical structure. The core function of chelerythrine is as a biochemical research tool for studying various cellular processes and signaling pathways.

Automatically generated - may contain errors

2 protocols using chelerythrine

1

Alkaloid Profiling of Medicinal Plants

Check if the same lab product or an alternative is used in the 5 most similar protocols
Acetonitrile (ACN), methanol (MeOH, and 1-butyl-3-methylimidazolium tetrafluoroborate of chromatographic quality were received from E. Merck (Darmstadt, Germany). Dimethyl sulfoxide (DMSO) was from Sigma-Aldrich (Saint Louis, MO, USA).
Alkaloid standards (sanguinarine, chelerythrine, magnoflorine, palmatine, protopine and chelidonine) were purchased from Chem Faces Biochemical Co., Ltd. (Wuhan, China). Berberine was purchased from Sigma-Aldrich (St. Louis, MO, USA).
Plant materials were collected and identified in the Botanical Garden of Maria Curie-Skłodowska University in Lublin (Poland). Voucher specimens no. 12/2021 are available in the collection of the Department of Inorganic Chemistry, Medical University, Lublin. Sanguinaria canadensis was collected before flowering in March, during flowering in April and after flowering in June 2020. Mahonia aquifolium was collected during flowering in April. Chelidonium majus was collected before flowering in April, during flowering in May and after flowering in June 2018 and 2020. Plant organs were cut into pieces and dried at ambient temperature for 2 weeks.
+ Open protocol
+ Expand
2

Brazilin and Chelerythrine Cytoprotection

Check if the same lab product or an alternative is used in the 5 most similar protocols
Brazilin (CAS no. 474-07-7; purity ≥98%) and chelerythrine (CAS no. 34316-15-9; purity ≥98%) were purchased from Wuhan ChemFaces Biochemical Co., Ltd. (Wuhan, China). Brazilin and chelerythrine were dissolved in dimethyl sulphoxide (DMSO) (Sigma-Aldrich; Merck KGaA), and further diluted with culture medium until DMSO concentration was <0.1%. Five different drug concentrations of Brazilin (2.5, 5, 10, 25 and 50 µM) were given for 1 h prior to hypoxia stimulation. Cells were also pretreated with 1 µM chelerythrine for 1 h before Brazilin treatment in order to repress PKC activation, as described previously (22 (link)).
+ Open protocol
+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required

Sign up now

Revolutionizing how scientists
search and build protocols!