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Fib 14

Manufactured by Bio-Techne
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Sourced in United Kingdom

Fib-14 is a laboratory equipment product offered by Bio-Techne. It is designed to perform fibrinogen analysis. The core function of Fib-14 is to measure the concentration of fibrinogen in biological samples.

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Lab products found in correlation

Scrambled sirna, by Thermo Fisher Scientific (1 mentions) Nsc23766, by Santa Cruz Biotechnology (1 mentions) Grgdsp, by Merck Group (1 mentions) Microliter 701, by Hamilton Company (1 mentions)

2 protocols using fib 14

1

Intracerebroventricular drug administration in SAH

Cited 2 times
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Intracerebroventricular drug administration was performed as reported previously20 (link)–21 (link). A burr hole was drilled into the skull according to the following coordinates relative to bregma: 1.5 mm posterior and 1.0 mm lateral. The needle of a 10µL Hamilton syringe (Microliter 701; Hamilton Company, Reno, NV) was inserted through the burr hole into the left lateral ventricle through the burr hole 4.0 mm below the horizontal plane of bregma. Sterile PBS vehicle or 5ul rOPN (0.1ng in 5ul; EMD Chemicals, La Jolla, CA) were administered 3 hours after SAH induction by a pump at a rate of 0.5 ul /min., respectively. GRGDSP (Sigma-Aldrich, St. Louis, MO; 100pmol in 1uL), Fib-14 (Tocris Bioscience, Ellisville, MI; 0.2 mg in 5 µL PBS) or NSC23766 (Santa Cruz Biotechnology; 30ug/5ul) was administered 1 hour before SAH induction. 500 pmol/5ul ILK siRNA or scrambled siRNA (Life Technologies) was infused at the same rate 48 hours before SAH modeling.
Wu J., Zhang Y., Yang P., Enkhjargal B., Manaenko A., Tang J., Pearce W.J., Hartman R., Obenaus A., Chen G, & Zhang J.H. (2016). rOsteopontin Stabilizes Smooth Muscle Cell Phenotype via Integrin Receptor/ILK/Rac-1 Pathway after SAH in Rats. Stroke; a journal of cerebral circulation, 47(5), 1319-1327.
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2

Fib-14 Inhibitor Reduces Brain Injury

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FAK inhibitor 14 (Fib‐14) (30 mg/kg; Tocris Bioscience, Bristol, UK)18 dissolved in PBS was administered by intraperitoneal injection with a total volume of 200 μL at 1 hour before SAH induction and then followed with NTN‐1 (45 μg/kg) treatment. Neurobehavioral scores, brain water content, and Western blot were detected at 24 hours after SAH.
Xie Z., Enkhjargal B., Reis C., Huang L., Wan W., Tang J., Cheng Y, & Zhang J.H. (2017). Netrin‐1 Preserves Blood‐Brain Barrier Integrity Through Deleted in Colorectal Cancer/Focal Adhesion Kinase/RhoA Signaling Pathway Following Subarachnoid Hemorrhage in Rats. Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 6(5), e005198.
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