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1h 1 2 4 oxadiazole 4 3 a quinoxalin 1 one

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1H-[1,2,4]oxadiazole[4,3-a]quinoxalin-1-one is a chemical compound used in laboratory settings. It is a heterocyclic organic compound consisting of a quinoxaline ring fused to an oxadiazole ring. The compound can be utilized as a reagent or intermediate in various chemical reactions and analyses.

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Lab products found in correlation

Ng nitro l arginine methyl ester l name, by Merck Group (2 mentions) Adenosine deaminase ada, by Roche (1 mentions) N6 cyclopentyladenosine, by Bio-Techne (1 mentions) Acetylcholine chloride, by Merck Group (1 mentions) Phenylephrine, by Merck Group (1 mentions)

2 protocols using 1h 1 2 4 oxadiazole 4 3 a quinoxalin 1 one

1

Adenosine and PKG Signaling Modulation

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N6-cyclopentyladenosine (CPA) was purchased from Tocris, (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-methoxy-2,9-dimet-hyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3′,2′,1′-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methylester (KT5823) was from Santa Cruz Biotecnology, 1H-[1,2,4]oxadiazole[4,3-a]quinoxalin-1-one (ODQ) and NG-nitro-L-arginine methylester (L-NAME) were from Sigma and Adenosine deaminase (ADA) was from Roche. All other reagents used were from analytical grade.
Pinto I., Serpa A., Sebastião A.M, & Cascalheira J.F. (2016). The Role of cGMP on Adenosine A1 Receptor-mediated Inhibition of Synaptic Transmission at the Hippocampus. Frontiers in Pharmacology, 7, 103.
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2

Pharmacological Modulation of Vascular Function

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Phenylephrine (PHE), acetylcholine chloride (ACh), NG-nitro-L-arginine methyl ester (L-NAME), 1H-[1,2,4]Oxadiazole[4,3-a]quinoxalin-1-one (ODQ), 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide (PTIO), glibenclamide (GLIB), 4-aminopyridine (4-AP), tetraethylammonium chloride (TEA), apamin (APM) and charybdotoxin (ChTX) were obtained from Sigma-Aldrich (USA).
ODQ and GLIB were dissolved in dimethyl sulfoxide (DMSO, 0.1%); PTIO in ethanol; and APM in 0.05 M acetic acid. The other drugs and reagents were dissolved in distilled water.
de Carvalho E.F., Nunes A.F., Silva N.C., da Silva Gomes J.P., de Sousa R.P., Silva V.G., Nunes P.H., Santos R.F., Chaves M.H., Oliveira A.P, & Oliveira R.C. (2019). Terminalia fagifolia Mart. & Zucc. elicits vasorelaxation of rat thoracic aorta through nitric oxide and K+ channels dependent mechanism. Biology Open, 8(2), bio035238.
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