Phosphoric acid

Manufactured by Kanto Chemical

Sourced in Japan

Phosphoric acid is a clear, colorless, and odorless liquid chemical compound. It is a strong mineral acid with the chemical formula H3PO4. Phosphoric acid is commonly used in various industrial and laboratory applications.

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Lab products found in correlation

Acetonitrile, by Kanto Chemical (2 mentions) Milli q integral 5, by Merck Group (1 mentions) Perchloric acid, by Junsei (1 mentions) Acetone, by Kanto Chemical (1 mentions) Ethanol, by Kanto Chemical (1 mentions) Sodium azide, by Fujifilm (1 mentions) Hydrochloric acid solution, by Fujifilm (1 mentions) Distilled water, by Fujifilm (1 mentions) Sodium dihydrogenphosphate dihydrate, by Nacalai Tesque (1 mentions) Diethyl ether, by Kanto Chemical (1 mentions) Sodium phosphate buffer, by Nacalai Tesque (1 mentions) Human serum albumin (hsa), by Merck Group (1 mentions) Distilled water, by Kanto Chemical (1 mentions) Calcium chloride, by Kanto Chemical (1 mentions) Casio3, by Fujifilm (1 mentions) Isopropanol, by Fujifilm (1 mentions) Hydrochloric acid (hcl), by Kanto Chemical (1 mentions) Dimethylnitrosamine, by Merck Group (1 mentions) Hydroxyproline, by Merck Group (1 mentions) P dimethylaminobenzaldehyde, by Merck Group (1 mentions)

7 protocols using phosphoric acid

Electrochemical Deposition on Aluminum

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Acetone (EL grade) and 99.5%
ethyl alcohol (guaranteed reagent grade) were purchased from Junsei
Chemical Co., Ltd. Perchloric acid (60%) (HClO₄, guaranteed
reagent grade) and chromic anhydride (guaranteed reagent grade) were
purchased from FUJIFILM Wako Pure Chemical Corporation. Phosphoric
acid (85%) (H₃PO_4, guaranteed reagent grade)
and 0.1 mol/L sodium hydroxide solution (for volumetric titration)
were purchased from Kanto Chemical Co., Inc. A high purity aluminum
plate (purity of 99.99%, 1 mm in thickness) was purchased from Showa
Denko K. K. A platinum plate (purity of 99.98%, 0.10 mm in thickness)
was purchased from The Nilaco Corporation. An aqueous dispersion of
commercial silica nanoparticles (Snowtex MP-4540M, silica concentration
of 40 wt %, pH value of 9.3) was provided by Nissan Chemical Corporation.
Deionized water (DI water) with a resistivity of 18.2 MΩ·cm
that was obtained from Milli Q integral5 (Merck Millipore) was used
in all experiments.

Sekiguchi K., Nakanishi T., Segawa H, & Yasumori A. (2019). Fabrication of Silica Nanoparticle Monolayer Arrays Using an Anodic Aluminum Oxide Template. ACS Omega, 4(10), 14333-14339.

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Chlorine Dioxide Generation and Measurement

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In this study, we used 3.35% sodium chlorite solution (Purogene, Fuji Techno Service Co.,
Ltd., Sendai, Japan) and 85% phosphoric acid (Kanto Chemical Co., Inc., Tokyo, Japan)
without dilution. ClO₂ gas was generated by mixing the sodium chlorite solution
and phosphoric acid. The resulting chemical reaction is as follows: 15NaClO₂ +
4H₃PO₄ → 12ClO₂ + 6H₂O + 3NaCl +
4Na₃PO₄. The concentration of gas was measured with either of two
distinct ClO₂ detector tubes (No. 23M: detection range of 0.1 ppm−10 ppm, No.
8H: detection range of 12.5 ppm−250 ppm, Gastec Co., Inc., Ayase, Japan). When using the
No. 8H detector tube, the gas concentration was corrected using the conversion factor
obtained by following the written instructions.

Shirasaki Y., Matsuura A., Uekusa M., Ito Y, & Hayashi T. (2016). A study of the properties of chlorine dioxide gas as a fumigant. Experimental Animals, 65(3), 303-310.

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Synthesis of Inorganic Compounds

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Calcium hydroxide (purity > 96.0%), ethanol (> 99.5%), glycerin (> 99.0%), phosphoric acid (> 85.0%), and acetone (> 99.5%) were purchased from Kanto Chemical (Tokyo, Japan) and used as received.

Sawada M., Sridhar K., Kanda Y, & Yamanaka S. (2021). Pure hydroxyapatite synthesis originating from amorphous calcium carbonate. Scientific Reports, 11, 11546.

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Synthesis and Characterization of DMATMPyP

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DMATMPyP
was obtained by the methylation
of meso-(N,N-dimethyl-4-aminophenyl)-tris(p-pyridyl)porphyrin (DMATPyP). Synthesis of DMATPyP was
according to the previously reported method.^{47 (link)} To obtain DMATMPyP, the methylation of DMATPyP was carried out according
to the literature.^{48 (link),49 (link)} Details about the synthesis and
characterization of DMATMPyP are described in the Supporting Information. The spectroscopic-grade distilled
water was purchased from Dojin Chemicals Co. (Kumamoto, Japan). Sodium
phosphate buffer (pH 7.6) and NADH were from Nakalai Tesque Inc. (Kyoto,
Japan). Dimethyl sulfoxide-d₆ and sodium
azide were from FUJIFILM Wako Pure Chemical Co. (Osaka, Japan). Methyl
iodide and diethyl ether were from Kanto Chemical Co., Inc. (Tokyo,
Japan). HSA was purchased from Sigma-Aldrich Co. LLC. (St. Louis,
MO, USA). These reagents were used as received. A sodium phosphate
buffer (pH 6.4) was prepared from disodium hydrogen phosphate dodecahydrate
and sodium dihydrogen phosphate dihydrate (Nacalai Tesque, Inc., Kyoto,
Japan). Sodium phosphate buffers (pH 4.4 and 3.2) were prepared from
sodium dihydrogen phosphate dihydrate (Nacalai Tesque, Inc.) and 0.05
M phosphoric acid (Kanto Chemical, Co. Inc., Tokyo. Japan). An acidic
solution (pH 2.0) was prepared from 0.1 M hydrochloric acid solution
(FUJIFILM Wako Pure Chemical Co.) and distilled water (FUJIFILM Wako
Pure Chemical Co.).

Hirakawa K., Takai S., Horiuchi H, & Okazaki S. (2020). Photooxidation Activity Control of Dimethylaminophenyl-tris-(N-methyl-4-pridinio)porphyrin by pH. ACS Omega, 5(42), 27702-27708.

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Pharmaceutical Synthesis and Characterization

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PS300 was generously provided by Tomita Pharmaceutical Co., Ltd. (Tokushima, Japan). CaSiO₃ was purchased from Wako Pure Chemical Industries, Ltd. (Osaka, Japan). IBU was generously provided by Kaken Pharmaceutical Co., Ltd. (Tokyo, Japan). Zirconia beads of 0.3 mm in diameter were purchased from Nikkato Co., Ltd. (Osaka, Japan). Ethanol, 1 mol/L sodium hydroxide solution, calcium chloride, phosphoric acid, acetonitrile, and distilled water were purchased from Kanto Chemical Co., Inc. (Tokyo, Japan). All received chemicals and solvents were of analytical reagent grade.

Kawano Y., Chen S, & Hanawa T. (2021). Solubility Enhancement of Ibuprofen by Adsorption onto Spherical Porous Calcium Silicate. Pharmaceutics, 13(6), 767.

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Dimethylnitrosamine-Induced Liver Injury Assay

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Dimethylnitrosamine (N-nitrosodimethylamine or DMN), 1,1,3,3-tetraethoxypropane (TEP), chloramine-T, p-dimethylaminobenzaldehyde, hydroxyproline, potassium chloride (KCl), and trichloroacetic acid (TCA) were purchased from Sigma (St. Louis, MO, United States); Thiobarbituric acid (TBA) was purchased from Lancaster Co. (Lancashire, United Kingdom). Hydrochloric acid and phosphoric acid were from Kanto Chemical Co., Inc. (Tokyo, Japan); n-butanol was purchased from J. T. Baker (Center Valley, PA, United States); Mayer's haematoxylin and isopropanol were obtained from Wako Pure Chemical Industries (Osaka, Japan); Goat anti-human connective tissue growth factor (CTGF) antibody, CTFG standard solution, rabbit anti-human CTGF antibody, and anti-rabbit immunoglobulin G horseradish peroxidase conjugate were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, United States), and DDB was purchased from Pharma King Co., Ltd. (Gyeonggi-do, Republic of Korea).

Kim H.S., Kim H.G., Lee H.W., Lee S.B., Lee J.S., Im H.J., Kim W.Y., Lee D.S, & Son C.G. (2016). A Herbal Formula, CGXII, Exerts Antihepatofibrotic Effect in Dimethylnitrosamine-Induced SD Rat Model. Evidence-based Complementary and Alternative Medicine : eCAM, 2016, 5093718.

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Phosphate Buffer Excipient Preparation

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HPMC (METOLOSE®, 90SH-4000, MW: 300,000, viscosity 4000 mPa•s, methoxy group 22.0-24.0%, hydroxypropyl group 8.5-10.5%) and MC (METOLOSE®, SM-1500) were purchased from Shin-Etsu Chemical Co., Ltd, Tokyo, Japan. Sodium dihydrogen phosphate and dihydrate, disodium hydrogen phosphate and 12 hydrates, phosphoric acid, acetonitrile, and purified water were purchased from Kanto Chemical Co., Inc., Tokyo, Japan.

Natori N., Shibano Y., Hiroki A., Taguchi M., Miyajima A., Yoshizawa K., Kawano Y, & Hanawa T. (2023). Preparation and Evaluation of Hydrogel Film Containing Tramadol for Reduction of Peripheral Neuropathic Pain. Journal of pharmaceutical sciences, 112(1).

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