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B6.129s4 il2rgtm1wjl j

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B6.129S4-Il2rgtm1Wjl/J is a mouse strain that is characterized by a targeted mutation in the interleukin 2 receptor gamma chain (Il2rg) gene. This strain is commonly used in immunological research.

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Lab products found in correlation

B6.129s4 ccr2tm1ifc j, by Jackson ImmunoResearch (1 mentions) B6.129s7 rag1tm1mom j, by Jackson ImmunoResearch (1 mentions) C57bl 6j, by Jackson ImmunoResearch (1 mentions) B6 cg rag2tm1.1cgn j, by Jackson ImmunoResearch (1 mentions)

Spelling variants of this product

B6.129S4-Il2rgtm1Wjl/J mice (3 citations) Il2rg−/− (B6.129S4-Il2rgtm1Wjl/J, (2 citations)

2 protocols using b6.129s4 il2rgtm1wjl j

1

Mice Models for Immunological Studies

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Female wildtype (C57Bl/6J, #000664), CCR2-null (B6.129S4-Ccr2tm1Ifc/J, #004999), RAG1-null (B6.129S7-Rag1tm1Mom/J, #002216) and IL2Rγ-null (B6.129S4-Il2rgtm1Wjl/J, #003174) mice were purchased from Jackson Labs. RAG1/IL2Rγ mice were created by crossing female RAG1 mice to male IL2Rγ mice. Six to eight week-old mice were used for all experiments. The animals were housed in a vivarium maintained on a 12-hour light/dark schedule with a temperature of 22 ± 1°C and a relative humidity of 50 ± 5%. Food and water were available ad libitum.
Zemp F.J., McKenzie B.A., Lun X., Reilly K.M., McFadden G., Yong V.W, & Forsyth P.A. (2014). Cellular factors promoting resistance to effective treatment of glioma with oncolytic Myxoma virus. Cancer research, 74(24), 7260-7273.
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2

Generation and Maintenance of Ebf1 Mutant Mice

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Ebf1+/ mice were provided by R. Grosschedl (Max Planck Institute of Immunobiology and Epigenetics). Ebf1-deficient embryos were generated from Ebf1+/ intercrosses. https://www.jax.org/strain/002320 B6.Cg-Tg(BCL2)25Wehi/J (Bcl2-Tg), B6.Gt(ROSA)26Sortm1.1(CAG-cas9*,-EGFP)Fezh/J (Cas9 knock-in), B6.Cg-Rag2tm1.1Cgn/J (RAG2 KO), and B6.129S4-Il2rgtm1Wjl/J (Cγ KO) mice were purchased from the Jackson Laboratory. All mice were maintained in specific pathogen free conditions, and animal experiments were approved by the Animal Experimentation Committee (Tokai University, Kanagawa, Japan).
Hirano K.I., Hosokawa H., Koizumi M., Endo Y., Yahata T., Ando K, & Hozumi K. (2021). LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice. eLife, 10, e68227.
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