Reagents were purchased from
Chem-Impex International, Aldrich, Fluka, and Sigma-Aldrich Co. and
used without further purification unless otherwise noted. All solvents
for syntheses were anhydrous. Thin layer chromatography was performed
with precoated aluminum-backed TLC plates obtained from VWR: Aluminum
Oxide 60, Neutral F254 & Silica Gel 60, Neutral F254. Visualization
of TLC plates was performed with ninhydrin, iodine, or an UVGL-25
Compact UV Lamp 254/365 UV (UVP 115 V ∼ 60 Hz/0.16 Amps). Purifications
were performed either with aluminum oxide (Brockmann I, Sigma-Aldrich),
silica (Silicycle, Quebec City, Canada), or on a Biotage Isolera 4
Purification System equipped with a 200–400 nm diode array
detector. For flash purifications, Biotage SNAP Flash Chromatography
Cartridges were used (KP-C18-Sil & KP-NH).
Chem-Impex International, Aldrich, Fluka, and Sigma-Aldrich Co. and
used without further purification unless otherwise noted. All solvents
for syntheses were anhydrous. Thin layer chromatography was performed
with precoated aluminum-backed TLC plates obtained from VWR: Aluminum
Oxide 60, Neutral F254 & Silica Gel 60, Neutral F254. Visualization
of TLC plates was performed with ninhydrin, iodine, or an UVGL-25
Compact UV Lamp 254/365 UV (UVP 115 V ∼ 60 Hz/0.16 Amps). Purifications
were performed either with aluminum oxide (Brockmann I, Sigma-Aldrich),
silica (Silicycle, Quebec City, Canada), or on a Biotage Isolera 4
Purification System equipped with a 200–400 nm diode array
detector. For flash purifications, Biotage SNAP Flash Chromatography
Cartridges were used (KP-C18-Sil & KP-NH).