Patients undergoing OCT for various clinical indications at our institution were reviewed. The OCT acquisition was performed using the C7 Dragonfly™ intracoronary imaging catheter and the ILUMIEN™ PCI Optimization System (St. Jude Medical). All images were acquired using a non-occlusive technique with injection of isosmolar iodixonoal (Visipaque™ by GE healthcare) contrast using automatic injection to clear the vessel of blood [9] (link). The lesion was crossed using a routine angioplasty wire. The imaging catheter was then advanced over the wire. Once the catheter was positioned distal to the lesion it was pull backed using an automated motor at a speed of 15 mm/s.
C7 dragonfly
Manufactured by Abbott
Sourced in United States
The C7 Dragonfly is a compact and versatile laboratory instrument designed for a range of analytical applications. It features high-performance optics and advanced sensor technology to provide accurate and reliable measurements. The core function of the C7 Dragonfly is to facilitate precise data collection and analysis, enabling researchers and scientists to obtain valuable insights from their samples.
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Lab products found in correlation
8 protocols using c7 dragonfly
1
Intracoronary OCT Imaging Technique
2
In Vivo NIRS and OCT Imaging
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After in vitro NIRS measurements, the measurement locations were marked with a felt tip pen. These points were imaged with OCT (λ = 1305 ± 55 nm, axial resolution < 20 µm, lateral resolution 25–60 µm; Ilumien PCI Optimization System, St. Jude Medical, St. Paul, MN, USA) by aligning a catheter (C7 Dragonfly, St. Jude Medical) over the measurement points (Fig. 1b ) and performing a pullback imaging, thus imaging the NIRS measurement locations and the surrounding tissue (Fig. 2a–c ). The samples were submerged in phosphate-buffered saline (PBS) during the imaging. Cartilage thickness was then determined from the OCT images of each location for biomechanical measurements.
3
Swept-Source OCT Tissue Imaging
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A commercially available swept-source OCT system (Illumien, St. Jude Medical) was
used, operating at a wavelength of 1300 nm with a bandwidth of 55 nm. The OCT
system is interfaced to a 0.9-mm-thick fiber-optic OCT probe (C7-Dragonfly, St.
Jude Medical). A typical OCT scan is performed in 5.4 seconds, producing a
cylindrical 540-slice dataset with dimensions 10 × 10 × 540 mm and an axial and
lateral resolution of 15 µm and 25 µm, respectively. Data were stored as Tiff
stacks for further processing. Unprocessed OCT images are directly available for
review on the console.
used, operating at a wavelength of 1300 nm with a bandwidth of 55 nm. The OCT
system is interfaced to a 0.9-mm-thick fiber-optic OCT probe (C7-Dragonfly, St.
Jude Medical). A typical OCT scan is performed in 5.4 seconds, producing a
cylindrical 540-slice dataset with dimensions 10 × 10 × 540 mm and an axial and
lateral resolution of 15 µm and 25 µm, respectively. Data were stored as Tiff
stacks for further processing. Unprocessed OCT images are directly available for
review on the console.
4
Quantifying Articular Cartilage Thickness via OCT
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We used an OCT device (wavelength 1,305 ± 55 nm; Ilumien PCI Optimization System; St. Jude Medical, St. Paul, MN) with a thin catheter (0.9 mm diameter; C7 Dragonfly; St. Jude Medical), providing cross-sectional images (axial resolution <20 μm). The sample and the catheter were placed in phosphate-buffered saline (PBS) during the imaging process, with the catheter held manually above the ink marking or lesion, which were both visible in the OCT image. The thin low-scattering layer observed in OCT images just above the subchondral bone is assumed to correspond to calcified cartilage (Cernohorsky et al. 2012 (link)). The thickness of the non-calcified cartilage used in mechanical measurements was measured from the site of interest using the OCT system software. After matching the measurement points in the OCT and microscopy images, the thicknesses of non-calcified cartilage, calcified cartilage, and full cartilage were measured again from the raw images, taking into account the refractive index of cartilage (1.358; Wang et al. 2010 (link)). Pixel size was determined based on the known diameter of the OCT catheter and considering the refractive index of the water inside the catheter (1.322).
5
OCT Analysis of BES Implantation
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The follow-up OCT examination was performed 8–12 months after BES implantation. The frequency-domain OCT system (C7 Dragonfly™ or C8 Dragonfly™; St. Jude Medical, St. Paul, MN, USA) was used in the present study. OCT examination was performed, as previously reported [11 (link)]. In the use of the frequency-domain OCT system, a 0.014-inch standard guide wire was positioned distally in the target vessel and the frequency OCT catheter was advanced to the distal end of the target lesion. The entire length of the region of interest was scanned using the integrated automated pullback device at 10 or 20 mm/s. For image acquisition, blood in the coronary artery was replaced with iodine contrast media and continuously flushed.
6
OCT Imaging in Aorta with Contrast Agent
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For OCT imaging, an ILUMIEN Optis system (St. Jude Medical) with a swept source at 1305 AE 55 nm at 22.6 mW was used, which enabled an A-scan depth of 7 mm in air and 4.83 mm in the used contrast agent. Therefore, the imaging depth of OCT in tissue should be 7 mm∕n_tissue, n: 1.33 to 1.55. The system had an A-scan repetition rate of 90 kHz that allows a frame rate of 180 images per second. As catheter, the corresponding C7 Dragonfly (St. Jude Medical) was used. The catheter was inserted through a 6F introducer (B. Braun, Melsungen, Germany) attached to a guidewire (Terumo, Tokyo, Japan), which was advanced into the descending aorta. Before the OCT imaging, the contrast agent was manually injected into the side port of the imaging catheter. The software of the ILUMEN system recognized the purging with the contrast agent and automatically started a pullback sequence with the predetermined length of 40 mm. All data were saved to the ILUMEN system and reviewed with the help of a cardiologist.
7
Comparative Intravascular Imaging Techniques
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The following materials were used for the interventions: Guidewire (Pilot 50, Abbott Vascular, Santa Clara, CA, USA), IVUS catheter (Atlantis SR pro, 40 MHz, Boston Scientific, Natick, MA, USA) and OCT catheters (C7 DragonflyTM St Jude Medical, St Paul, MN, USA aided by a Twin-pass catheter, Vascular Solutions Inc. Minneapolis MN, USA).
The following stents were used: Xience V (Everolimus eluting stent, Abbott Vascular, Santa Clara, CA, USA), Biomatrix (Biolimus eluting stent, Biosensors Int. Singapore), Focus NP (Sirolimus eluting stent, Envision Ltd. Surat, India) and Amazonia Croco (BMS, Minvasys, Gennevilliers, France).
The following stents were used: Xience V (Everolimus eluting stent, Abbott Vascular, Santa Clara, CA, USA), Biomatrix (Biolimus eluting stent, Biosensors Int. Singapore), Focus NP (Sirolimus eluting stent, Envision Ltd. Surat, India) and Amazonia Croco (BMS, Minvasys, Gennevilliers, France).
8
Intravascular OCT Imaging Techniques
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Images were acquired using a commercially available timedomain (M2 Cardiology Imaging System, LightLab Imaging, Westford, MA, USA) or frequency-domain (C7 Dragonfly TM , St. Jude Medical, St. Paul, MN, USA) OCT system. Briefly, the M2 system uses an occlusion balloon (Helios TM , LightLab Imaging Inc., Boston, MA, USA) that is inflated proximal to the lesion at 0.4-0.6 atm during image acquisition. The imaging wire is automatically pulled back from a distal to a proximal position at a rate of 1.0 mm/s, and saline or Ringer's solution is continuously infused from the tip of the occlusion balloon. In the C7 system, a 2.7-F OCT imaging catheter is advanced distal to the lesion, and automated pullback (20 mm/s) is initiated and coincides with blood clearance via the injection of contrast medium.
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