MRI exams were performed using a 1.5T GE Optima 450w scanner (GE Healthcare, Waukesha, WI) with a maximum gradient amplitude of 34mT/m and slew rate of 150 mT/m/ms. Patients underwent different imaging sequences depending on indication and radiologist preference. All patients underwent a gadolinium-enhanced MRI exam and received intravenous injections of Gadavist (Bayer AG, Leverkusen, Germany), Omniscan (GE Healthcare, Little Chalfont, UK), MultiHance (Bracco Imaging, Milan, Italy), Magnivist (Bayer AG), or Ablavar (Lantheus Medical Imaging, North Bilerica, MA). Detailed exam information, including individual sequences performed, time of sequence, and specific absorption rate (SAR), were collected for each patient. Specific absorptions (SA) were calculated for each sequence by multiplying sequence time (seconds) by SAR. Maximum SA, total SA, and highest SAR were calculated for each patient.
Optima 450w scanner
Manufactured by GE Healthcare
Sourced in United States
The Optima 450w scanner is a laboratory equipment designed for high-quality imaging. It is capable of scanning a variety of samples and provides accurate data for research and analysis purposes.
Automatically generated - may contain errors
4 protocols using optima 450w scanner
1
Quantifying MRI Exposure Parameters
2
Quantitative analysis of acute ischemic stroke using DWI
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Magnetic resonance imaging (MRI) was performed within the first 48 h from the onset of stroke symptoms by a 1.5 tesla Optima 450 w scanner (G.E. Healthcare, Chicago, IL, USA). The investigation was conducted in the Department of Radiology at the University Hospital No. 1 in Bydgoszcz. The quantitative analysis of diffusion-weighted imaging (DWI) was assessed by standard diagnostic software package (Functool 4.4, Advantage Workstation 4.4, G.E.Healthcare, Chicago, IL, USA). We set proper threshold values of signal intensities in the series of DWI images to remain only voxels overlapping with the ischemic focus. Then, we manually removed other voxels located outside the area of interest (e.g., noise) within the selected intensity range. Finally, we used a special dedicated function for automatic calculation of the volume of displayed voxels. We provided a final result of the size of acute ischemic infarct in cm3. On the basis of obtained volumes, we subdivided the participants into strokes with large and small acute ischemic size, setting the limit value at a volume of 2 cm3.
3
Hyperthermia Treatment Protocol Evaluation
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In this study, we collected data from 14 healthy female volunteers. The institutional review board approved this study using the protocol (MEC-2014-096). All volunteers were positioned inside the BSD-2000-3D MR compatible system (Pyrexar Medical Cop., Salt Lake City, UT, USA) [19] (link), [20] (link), which is integrated into a 1.5T GE Optima 450W scanner (General Electric Healthcare, Waukesha, WI, USA).
As shown in Fig.1 , we took MR images of the volunteers in the planning and treatment setup. The planning setup intends to mimic the imaging setup used for the current HTP, and the treatment setup reproduces the hyperthermia treatment. Regarding the MR imaging protocol, we used the 3D spoiled gradient recalled echo (SPGR) pulse sequence to visualize gastrointestinal air and the PROPELLER sequence to obtain high-resolution anatomic images. The details about the experiment and the MR protocol can be found in our previous work [21] (link).
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As shown in Fig.
Volunteer experiment setup: schematic representation of the volunteer in the planning and treatment setup, and the MR images taken at each setup. The column of the MR imaging represents the 3D SPGR images, and the second column denotes the images acquired using PROPELLER.
4
MR Arthrography Protocol for Joint Evaluation
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The patients who underwent an MR arthrogram study received a percutaneous intra-articular injection of diluted Gadovist contrast medium (1:400 normal saline dilution = 2.5 μmol/ml) under fluoroscopic or ultrasound guidance. A total of 12 or 15 mL diluted Gadovist contrast medium was injected into the joint space for female or male patients, respectively. The patient would then be transferred to the MRI machine for subsequent MR study. The MR imaging was performed using 1.5-T GE HDxt scanner or 1.5-T GE Optima 450w scanner, with a 32channel body array coil or a 32-channel cardiac coil. The patient was in supine position, keeping legs straight, and feet in neutral position, without internal or external rotation. No weighted traction was applied to separate both chondral surfaces. A protocol was applied including axial, coronal, and sagittal T1-weighted fast spin-echo image with fat suppression (repetition time/echo time [millisecond], 500-600/8-10), slice thickness of 4 mm, field of view (FOV) of 22 × 22 cm 2 ; coronal and sagittal T2-weighted fast spin-echo image with fat suppression (3000-4000/55-65), slice thickness of 4 mm, FOV of 22 × 22 cm 2 ; and oblique axial (along femoral neck axis) T1-weighted fast spin-echo image with fat suppression (500-600/8-10), slice thickness of 3 mm, FOV of 20 × 20 cm 2 .
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