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8 protocols using pcf pq260l

1

Crohn's Disease Imaging Techniques

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BAE was performed using a single-balloon enteroscope (SIF-Q260; Olympus Medical Systems, Tokyo, Japan). An expert endoscopist performed BAE and inserted it into the small bowel as deep as possible. When insertion was difficult owing to stenosis, imaging with a contrast medium injected from the scope was used to assess the lesions in the deeper parts. CS was performed using a conventional colonoscope (PCF-290ZI; PCF-PQ260L; Olympus Medical Systems, Tokyo, Japan). CS was performed using a conventional colonoscope (PCF-290ZI; PCF-PQ260L; Olympus Medical Systems, Tokyo, Japan). Conventional CS under fluoroscopy with contrast medium infusion was not included as small bowel imaging in this study. CE was performed using PillCam Small Bowel Capsule 3 (Medtronic, Minneapolis, MN, USA). All segments were retrospectively and separately scored using simple endoscopic score for Crohn’s disease (SES-CD) [24] (link) by endoscopists who were blinded to the biomarker results.
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2

Standardized Colonoscopy Procedure Protocol

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The scopes used were mainly PCF-H290I and PCF-Q260AI (Olympus), while a small-diameter long scope was used only rarely (PCF-PQ260L, Olympus). A short black hood was attached to the tip of the scope (MAJ-1990 or MAJ-1988, Olympus). Carbon dioxide (CO2) was used for insufflation with a CO2 insufflator (Olympus UCR Insufflator). A sedative was administered upon the patient’s request and with the physician’s permission; when administered, an intravenous injection of pethidine was predominantly used. The decision to administer an antispasmodic agent depended on the colonoscopist; when administered, butylscopolamine or glucagon was injected intravenously. Any lesion detected was not resected at the time, and in one case requiring resection, this was performed on another day. In Japan, nonresection of diminutive polyps is permitted; thus, only polyps of > 5 mm were judged to require resection. Withdrawal time was measured with a stopwatch during the examination; the endoscopic technician declared the time, and the colonoscopist recorded it in the report. If withdrawal time was missing from the report, the time was determined by consulting the times on the cecum and anal images as they were written on the recorded images.
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3

Efficacy of Small-Caliber Colonoscope

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This study was a post hoc analysis of an RCT investigating the efficacy of a small‐caliber colonoscope in preventing pain during colonoscopy in female patients. The trial was carried out at our institution between October 2013 and November 2017.10 The study enrolled 220 female patients ≥20 years of age who underwent non‐therapeutic colonoscopy without sedation. They were randomly assigned in a 1:1 ratio to undergo colonoscopy using a small‐caliber colonoscope (PCF‐PQ260L; Olympus Medical Systems, Tokyo, Japan) or a standard colonoscope (CF‐Q260AI; Olympus Medical Systems). Patients with a history of colorectal surgical resection, pregnancy, inflammatory bowel disease, massive hematochezia, and preference for sedation were excluded from the RCT. Furthermore, the current analysis also excluded patients with incomplete colonoscopy or insufficient documentation of the number of detected adenomas.
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4

Reducing Colonoscopy Pain in Women

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This study was a post-hoc analysis of an RCT that investigated the efficacy of a small-caliber colonoscope in reducing pain during colonoscopy in female patients[17 ]. The trial was conducted at our institution between October 2013 and November 2017. The study included 220 female patients aged ≥20 years who underwent unsedated colonoscopy. They were randomly assigned in a 1:1 ratio to either undergo the colonoscopy using a small-caliber (PCF-PQ260L; Olympus Medical Systems, Tokyo, Japan) or a standard (CF-Q260AI; Olympus Medical Systems) colonoscope.
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5

Endoscopic Sphincterotomy for Bile Duct Stones

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The ES procedure was basically carried out with a sphincterotome through a side-viewing duodenoscope (JF-240, TJF-240, JF-260V, TJF-260V; Olympus Medical Systems Co. Ltd., Tokyo, Japan). However, for the patients with surgically altered upper gastrointestinal anatomies (a Billroth II or Roux-en-Y anastomosis), a forward-viewing conventional endoscope (GIF-Q260, PCF-Q240 /260, PCF-PQ260L; Olympus Medical Systems) or double balloon endoscope (EN-450T5 /W, EC-450BI5; Fujifilm Medical Co. Ltd., Tokyo, Japan) or oblique-viewing endoscope (GIF-XK240; Olympus Medical Systems) was used. The incision length was basically based on the stone size within the oral protrusion (medium ES). However, in the cases of the dilated common bile duct (≥ 12 mm) with the large stone, EPLBD was performed following ES. During the ES, an electrosurgical generator unit (ERBE ICC200; Surgical Technology Group, Hampshire, England, UK) was put in ENDO CUT mode and switched to the 120-W power setting.
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6

Comparison of Small-Caliber and Standard Colonoscopes

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We used a PCF-PQ260 L for the small-caliber colonoscope group and a CF-Q260AI (Olympus Medical Systems, Tokyo, Japan) for the standard colonoscope group. Features of these colonoscopes are shown in
Fig. 1(left, PCF-PQ260L; right, CF-Q260AI). The small-caliber colonoscope has an outer diameter of 9.2 mm and a working length of 168 cm. In addition, the small-caliber colonoscope has a flexible passive bending section located close to the primary bending section at the distal side of the endoscope and a high-force transmission insertion tube for efficiently transmitting the force from the proximal to the distal side
20 (link)
. However, the variable-stiffness feature was not attached to the small-caliber colonoscope. On the other hand, the standard colonoscope has an outer diameter of 12.2 mm, a working length of 133 cm, and a variable stiffness feature. During colonoscopy, a 2-mm transparent cap was attached to the tip of the each colonoscope (distal attachment, small-caliber colonoscope; model MAJ-1988, standard colonoscope; model MAJ-1990, Olympus Medical Systems, Tokyo, Japan).
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7

Endoscopic Treatment for Colonic Diverticular Bleeding

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Considering the general condition of the patients, the operators decided to perform bowel preparation using either polyethylene glycol or an enema, and in some cases, no specific bowel preparation was performed. In most cases colonoscopy was performed using a PCF-Q260JI or PCF-H290I scope (Olympus Medical Systems, Tokyo, Japan). Other scopes (CF-Q260AI, PCF-H290Z, PCF-H290TI, or PCF-PQ260L, Olympus Medical Systems; EC-590MP, FUJIFILM, Saitama, Japan) were also used for colonoscopy. The scope was used with a soft cap (D201-10704, D201-11804, D201-12704, or D201-13404; Olympus Medical Systems) and water jet device in all colonoscopies. Endoscopic treatment for CDB with SRH was performed at the discretion of the individual operators. Clipping was predominantly conducted using hemoclips (HX-610-135S or HX-610-135, Olympus Medical Systems; ROCC-D-26-195-C, Micro-Tech, Nanjing, China). These hemoclips were used for the so-called direct method (Fig. 2d), where they were placed on the vessel as close to the bleeding as possible (23 (link)). In contrast, indirect clipping was performed in the Zipper fashion when either the source of the bleeding could not be confirmed due to massive bleeding or it was difficult to insert the clip into the diverticulum (23 (link)).
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8

Ileocolonoscopy Bowel Prep and SES-CD Scoring

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All patients ingested 1000 mL of polyethylene glycol (PEG) before MRE. After MRE, the patients were required to orally ingest 0 to 1000 mL of additional PEG for a total of 1000 to 2000 ml as a standard bowel preparation regimen for ileocolonoscopy. A long slim colonoscope (PCF-PQ260L; Olympus Medical Systems, Tokyo, Japan) was routinely utilized to enable deeper insertion through possible strictures in daily clinical practice for patients with CD. All segments were retrospectively and separately scored by the Simple Endoscopic Score for CD (SES-CD), and the scores of each segment were calculated to include the sum of the scores in five segments[18 (link)]. A segment was scored as 0 if it could not be reached by ileocolonoscopy. Endoscopic remission was defined as an SES-CD of <5[19 ]. SES-CD was retrospectively scored blinded to the results of MRE.
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