Griseofulvin

Manufactured by Fujifilm

Sourced in Japan

Griseofulvin is a microfine crystalline product used in the manufacturing of microbiological growth media. It serves as an antifungal agent, inhibiting the growth and development of fungal organisms.

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Lab products found in correlation

Theophylline, by Fujifilm (2 mentions) Glibenclamide, by Fujifilm (1 mentions) Dipyridamole, by Fujifilm (1 mentions) Antipyrine, by Fujifilm (1 mentions) Sodium nitroprusside dihydrate, by Merck Group (1 mentions) Fluorescein isothiocyanate dextran 4000 fd4, by Merck Group (1 mentions) Carboxy ptio c ptio, by Dojindo Laboratories (1 mentions) Dithiothreitol (dtt), by Fujifilm (1 mentions) Diclofenac, by Fujifilm (1 mentions)

3 protocols using griseofulvin

Solubility Measurement of Pharmaceutical Compounds

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Albendazole was purchased from Tokyo Chemical Industry Co., Ltd (Tokyo, Japan). Griseofulvin, dipyridamole, and glibenclamide were purchased from FUJIFILM Wako Pure Chemical Corporation (Osaka, Japan). An identical batch was used by all companies.
The Japanese Pharmacopeia (JP) 2^nd fluid for dissolution testing (12.5 mM KH₂PO₄ and 12.5 mM Na₂HPO₄, pH 6.8, buffer capacity 10 mM/ ΔpH) was used for the solubility measurement.

Ono A., Matsumura N., Kimoto T., Akiyama Y., Funaki S., Tamura N., Hayashi S., Kojima Y., Fushimi M., Sudaki H., Aihara R., Haruna Y., Jiko M., Iwasaki M., Fujita T, & Sugano K. (2019). Harmonizing solubility measurement to lower inter-laboratory variance – progress of consortium of biopharmaceutical tools (CoBiTo) in Japan. ADMET & DMPK, 7(3), 183-195.

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Evaluation of Pharmaceutical Compounds

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Sodium nitroprusside dihydrate (SNP) and fluorescein isothiocyanate-dextran 4,000 (FD-4) were obtained from Sigma-Aldrich Co. Ltd. (St. Louis, MO, USA). Carboxy-PTIO (c-PTIO) was obtained from Dojindo Laboratories (Kumamoto, Japan). Griseofulvin, antipyrine, theophylline, and sodium ferrocyanide decahydrate (SFC) were obtained from FUJIFILM Wako Pure Chemical Corporation (Osaka, Japan). Flurbiprofen was obtained from LKT Laboratories (St. Paul, MN, USA). Propranolol was obtained from Tokyo Chemical Industry Co., Ltd. (Tokyo, Japan). All other reagents were of analytical reagent grade.

Kishimoto H., Miyazaki K., Tedzuka H., Ozawa R., Kobayashi H., Shirasaka Y, & Inoue K. (2021). Utilization of Sodium Nitroprusside as an Intestinal Permeation Enhancer for Lipophilic Drug Absorption Improvement in the Rat Proximal Intestine. Molecules, 26(21), 6396.

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Evaluation of Permeability Enhancers

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NOC7 was obtained from Dojindo Laboratories (Kumamoto, Japan). Griseofulvin, diclofenac, theophylline, and dithiothreitol (DTT) were obtained from WAKO Pure Chemical Industries, Ltd. (Osaka, Japan). Antipyrine and FD-4 (MW 4000) were obtained from SigmaeAldrich Company Ltd. (St. Louis, MO). All other reagents were of analytical grade.

Kishimoto H., Miyazaki K., Takizawa Y., Shirasaka Y, & Inoue K. (2016). Absorption-Enhancing Effect of Nitric Oxide on the Absorption of Hydrophobic Drugs in Rat Duodenum. Journal of pharmaceutical sciences, 105(2).

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