Eight channel abdominal array and endorectal coil

All MRI examinations were performed on a GE Signa HDx 3.0 T magnet (GE Healthcare, Waukesha, WI) using an eight-channel abdominal array and endorectal coil (Medrad, Pittsburgh, PA), as previously described [21 (link)]. T1-weighted images were generated from spoiled gradient echo (SPGR) sequences with repetition time (TR)/echo time (TE)/α = 385 ms/6.2 ms/65°, over a 16-cm² field of view (FOV), 384 × 192 resolution and 3 mm slice thickness, T2-weighted images from fast relaxation fast spin echo (FRFSE) sequence, TR/TE = 3500 ms/102 ms over a 16-cm² FOV, with 384 × 224 resolution and 3 mm slice thickness, and DWI images from single-shot echo planar imaging (EPI) sequences, TR/TE = 2500 ms/65 ms with b-values of 0, 500 and 1400 s/mm²were acquired with 128 × 96 resolution and 3 mm slice thickness. DCE MRI was performed with a 3D SPGR sequence with full-gland coverage. Gadopentetate dimeglumine (Magnevist, Berlex Laboratories, Wayne, NJ) was injected intravenously (0.15 mmol/kg; rate 3 ml/s).

All MRI examinations were performed on a 3.0 T magnet (GE Signa HDx, GE Healthcare, Waukesha, WI) using an eight-channel abdominal array and endorectal coil (Medrad, Pittsburgh, PA), as previously described [23 (link),24 ]. Our protocol included: spoiled gradient echo (SPGR) T1-weighted sequences with repetition time (TR)/echo time (TE)/α = 385 ms/6.2 ms/65°, over a 16-cm2 field of view (FOV); fast relaxation fast spin echo (FRFSE) T2-weighted sequences with TR/TE = 3500 ms/102 ms over a 16-cm2 FOV; single-shot echo planar (EPI) DWI sequences with TR/TE = 2500 ms/65 ms and TR/TE = 3000 ms /80 ms for 0,500 0,1400 s/mm² b-values respectively. In addition, 3D SPGR DCE sequences were acquired with TR/TE/α = 3.6 ms/1.3 ms/15°, with full-gland coverage, and image voxel size of 1 × 1 × 6 mm³, as previously described [25 (link)]. Temporal resolution was 5 s, for a total observation time of 5 minutes Gadopentetate dimeglumine (Magnevist, Berlex Laboratories, Wayne, NJ) was injected intravenously (0.15 mmol/kg) at 3 mL/s injection rate.