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Cross carmellose sodium sd 711

Manufactured by FMC Biopolymer
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Sourced in Belgium

Cross-carmellose sodium SD-711 is a functional excipient used in the pharmaceutical industry. It is a cross-linked sodium carboxymethyl cellulose that acts as a disintegrant in solid dosage forms.

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Lab products found in correlation

Magnesium stearate, by Merck Group (2 mentions) Polyvinylpyrrolidone k90, by Merck Group (1 mentions) Polyvinylpyrrolidone pvp k90, by Merck Group (1 mentions) Pectin pec, by Merck Group (1 mentions)

2 protocols using cross carmellose sodium sd 711

1

Anhydrous Theophylline Tablet Formulation

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Anhydrous theophylline was purchased from Acors Organics. The excipients used for tablet compression were: directly compressible lactose monohydrate—Lactopress (BASF SE, Ludwigshafen, Germany), polyvinylpyrrolidone K90 (Sigma-Aldrich, Dorset, UK), microcrystalline cellulose (MCC) PH101 (FMC Biopolymer, Woluwe-Saint-Lambert, Belgium), cross-carmellose sodium SD-711 (FMC Biopolymer, Belgium), and magnesium stearate (Sigma–Aldrich Co., Ltd., Dorset, UK). The coating components were: sodium alginate (Alg, 15–20 cps) supplied by Sigma-Aldrich (Dorset, UK), ceresin wax supplied by Fisher Scientific (UK), glyceryl monostearate (Imwitor® 900K, GMS) donated by Cremer OLEO (Hamburg, Germany), citric acid monohydrate and pectin from citrus supplied by Sigma-Aldrich (USA), and fumaric acid purchased from Fischer Scientific (USA).
Habashy R., Khoder M., Isreb A, & Alhnan M.A. (2022). A Novel Multilayer Natural Coating for Fed-State Gastric Protection. Pharmaceutics, 14(2), 283.
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2

Developing Theophylline Anhydrous Formulations

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Theophylline anhydrous was purchased from Acros organics (New Jersey, USA). Directly compressible lactose monohydrate -Ludipress was supplied by BASF SE (Germany). Polyvinylpyrrolidone (PVP) K90, magnesium stearate and sodium alginate (Alg) (grade 15-20 cps) and pectin (Pec) from citrus fruits were supplied by Sigma-Aldrich Co., Ltd. (Dorset, UK). Microcrystalline cellulose (MCC) PH 101 and crosscarmellose sodium SD-711 were provided by FMC Biopolymer (Belgium). GMS (Imwittor K900) was a generous donation of IOI Oleo GmbH (Germany). The gastric medium consisted of a 0.1M hydrochloric acid solution (pH 1.2). The intestinal medium was made by adding 250 mL of 0.214 M tribasic phosphate to the gastric medium to raise the pH to 6.8.
Khoder M., Schropp V., Zeitler S., Pereira B., Habashy R., Royall P.G., Wang J.T, & Alhnan M.A. (2020). A novel natural GRAS-grade enteric coating for pharmaceutical and nutraceutical products. International journal of pharmaceutics, 584.
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