Unity inova 400 mhz

Manufactured by Agilent Technologies

The Unity Inova 400 MHz is a nuclear magnetic resonance (NMR) spectrometer designed for laboratory use. It operates at a frequency of 400 MHz and is capable of performing various NMR experiments for the analysis of chemical samples.

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Lab products found in correlation

Nmr as, by Agilent Technologies (2 mentions) Dmso d6, by Cambridge Isotopes (2 mentions) Cdcl3, by Cambridge Isotopes (1 mentions) Cd3od, by Cambridge Isotopes (1 mentions) Mercury 300 mhz, by Agilent Technologies (1 mentions)

Close spelling variants of this product

Unity Inova 400 MHz spectrometer Unity-Inova 400 MHz NMR spectrometer Unity Inova 400 INOVA 400 MHz Unity 400 MHz Unity Inova Inova 400 Unity 400

5 protocols using unity inova 400 mhz

Characterization of Organic Compounds

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Melting points were measured on an electro thermal digital melting point (Büchi, Germany) without calibration. ¹H-NMR spectra were recorded on Varian NMR AS and Varian Unity Inova 400 MHz NMR spectrometers. Chemical shifts were reported in parts per million (δ) units relative to the solvent peak. The ¹H NMR data were reported as peak multiplicities: s for singlet; d for doublet; t for triplet; q for quartet; and m for multiplet. Coupling constants were recorded in hertz (Hz). MS spectra were measured using Jeol JMS 700 high resolution mass spectrometer from the Korea Basic Science Institute (Daegu). Reagents were of commercial grade and were purchased from Sigma-Aldrich Co. (St. Louis, MI, USA), Merck (Darmstadt, Geramny), Duksan Pure Chemical Co (Ansan, Korea).

Yoo J., Park J., Kim D., Huh Y., Park Choo H.Y, & Woo H.A. (2022). Novel Benzoxazoles Containing 4-Amino-Butanamide Moiety Inhibited LPS-Induced Inflammation by Modulating IL-6 or IL-1β mRNA Expression. International Journal of Molecular Sciences, 23(10), 5331.

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Synthesis and Characterization of Pyridine-Hydantoin Derivatives

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Melting points were measured in open capillary tubes on a MelTemp melting point apparatus and are uncorrected. NMR spectra were recorded on either a Varian Mercury+ 300 Hz or a Varian UnityInova 400 MHz instrument. d₆-DMSO was purchased from Cambridge Isotope Laboratories. ¹H NMR were calibrated to 2.49 ppm for d₅-DMSO present in the d₆-DMSO solvent, and ¹³C NMR spectra were calibrated from the central peak at 39.7 ppm for d₆-DMSO. Coupling constants are reported in Hz. Scanned NMR spectra of compounds 15, 17–29 are contained in the Supplementary Material. Elemental analyses were obtained from Midwest Microlabs, Ltd. (Indianapolis, IN, USA), and high-resolution mass spectra were obtained from the COSMIC lab at Old Dominion University. Pyridinecarboxaldehydes were purchased from Acros, Ambeed, or Ark Pharm; hydantoin was purchased from Acros.

Schneider N.O., Gilreath K., Burkett D.J., St. Maurice M, & Donaldson W.A. (2024). Synthesis and Evaluation of 5-(Heteroarylmethylene)hydantoins as Glycogen Synthase Kinase-3β Inhibitors. Pharmaceuticals, 17(5), 570.

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Characterization of Organic Compounds

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Melting points were measured on an electro thermal digital melting point (Büchi, Germany) without calibration. ¹H-NMR spectra were recorded on Varian NMR AS and Varian Unity Inova 400 MHz NMR spectrometers. Chemical shifts were reported in parts per million (δ) units relative to the solvent peak. The ¹H NMR data were reported as peak multiplicities: s for singlet; d for doublet; t for triplet; q for quartet and m for multiplet. Coupling constants were recorded in Hertz (Hz). MS spectra were measured using a Jeol JMS 700 high resolution mass spectrometer from the Korea Basic Science Institute (Daegu). Reagents were of commercial grade and were purchased from Sigma-Aldrich Co., Merck, (St. Louis, MO, USA) and Duksan Pure Chemical Co., (Seoul, Korea).

Yoo J., Kim D., Park J., Kim Y.K., Park Choo H.Y, & Woo H.A. (2022). Novel Small Molecule Inhibitors Targeting the IL-6/STAT3 Pathway or IL-1β. Molecules, 27(9), 2696.

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NMR Characterization of FPBA, SVE, and Derivatives

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The ¹H and ¹¹B NMR spectra were recorded at 25 °C with a Varian Unity Inova 400 MHz spectrometer in quartz cuvettes using THF-d8 and DMF-d7 as solvents for FPBA and SVE, respectively, and CD₃OD as a solvent for Pyr-FPBA (16.7 g/L) and SVE-FPBA (10 g/L). The solvent peaks were taken as references in all measurements.

Hlavatovičová E., Fernandez-Alvarez R., Byś K., Kereïche S., Mandal T.K., Atanase L.I., Štěpánek M, & Uchman M. (2023). Stimuli-Responsive Triblock Terpolymer Conversion into Multi-Stimuli-Responsive Micelles with Dynamic Covalent Bonds for Drug Delivery through a Quick and Controllable Post-Polymerization Reaction. Pharmaceutics, 15(1), 288.

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Anhydrous Reaction Conditions and NMR Analysis

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All reactions involving moisture or air sensitive reagents were carried out under a nitrogen atmosphere in oven-dried glassware with anhydrous solvents. THF and ether were distilled from sodium/benzophenone. Purifications by chromatography were carried out using flash silica gel (32–63 μ). NMR spectra were recorded on either a Varian Mercury+ 300 MHz or a Varian UnityInova 400 MHz instrument. CDCl₃, CD₃OD and d₆-DMSO were purchased from Cambridge Isotope Laboratories. ¹H NMR spectra were calibrated to 7.27 ppm for residual CHCl₃, 3.35 ppm for CD₂HOD, or 2.49 ppm for d₅-DMSO. ¹³C NMR spectra were calibrated from the central peak at 77.23 ppm for CDCl₃, 49.3 ppm for CD₃OD, or 39.7 ppm for d₆-DMSO. Coupling constants are reported in Hz. Elemental analyses were obtained from Midwest Microlabs, Ltd., Indianapolis, IN, and high-resolution mass spectra were obtained from the COSMIC lab at Old Dominion University.

Murphy G.A., Moore M.S., Drivas G., de la Ossa P.P., Villamarin A., D’Eustachio P, & Rush M.G. (1997). A T42A Ran Mutation: Differential Interactions with Effectors and Regulators, and Defect in Nuclear Protein Import. Molecular Biology of the Cell, 8(12), 2591-2604.

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