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In vivo jetpei in vivo dna and sirna delivery reagent

Manufactured by Polyplus Transfection
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Sourced in United States

In vivo-jetPEI® is a cationic polymer-based reagent for the delivery of DNA and siRNA in vivo. It is designed to form stable complexes with nucleic acids, facilitating their uptake and transfection in various animal models.

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Lab products found in correlation

Survivin 6e4, by Abcam (2 mentions) Bcl xl, by Cell Signaling Technology (2 mentions) Mcl 1, by Santa Cruz Biotechnology (2 mentions) β actin ac 75, by Merck Group (2 mentions) Anti cleaved parp, by Cell Signaling Technology (1 mentions) Anti γh2ax, by Merck Group (1 mentions) Anti cyclin b, by Santa Cruz Biotechnology (1 mentions) Control inhibitors, by Bioneer (1 mentions) Anti β actin, by Santa Cruz Biotechnology (1 mentions) Control mimics, by Bioneer (1 mentions) Anti vegf, by Santa Cruz Biotechnology (1 mentions) Anti p cdc2, by Cell Signaling Technology (1 mentions) Anti caspase 3, by Cell Signaling Technology (1 mentions)

Spelling variants of this product

JetPEI (500 citations) JetPEI reagent (137 citations) In vivo-jetPEI (109 citations) In vivo-jetPEI reagent (16 citations) SiRNAs (4 citations)

3 protocols using in vivo jetpei in vivo dna and sirna delivery reagent

1

In vivo miRNA Inhibitor and Mimic Delivery

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The miRIDIAN has-miR-203 and has-miR-542-3p specific inhibitors, mimics, and their negative controls were purchased from Thermo Scientific Dharmacon (Lafayette, CO). In vivo-jetPEI®in vivo DNA and siRNA delivery reagent was purchased from Polyplus-transfection® SA (New York, NY). The Akt inhibitor VIII was purchased from EMD Chemicals, Inc. (Gibbstown, NJ). Paclitaxel (Ben Venue Labs, Inc., Bedford, OH) was obtained from University of Colorado Hospital pharmacy. The fully human anti-HER3 antibody MM-121 was kindly provided by Merrimack Pharmaceuticals Inc. (Cambridge, MA).
The primary antibodies used for western blot analyses were obtained as follows: Survivin (6E4) (Abcam, Cambridge, MA); Mcl-1 (Santa Cruz Biotechnology, Inc., Dallas, TX); Bcl-xl, caspase-8 (1C12), caspase-3 (8G10), and PARP (Cell Signaling Technology, Inc., Beverly, MA); β-actin (AC-75, Sigma-Aldrich, St. Louis, MO). All other reagents were purchased from Sigma-Aldrich unless otherwise specified.
Lyu H., Wang S., Huang J., Wang B., He Z, & Liu B. (2018). Survivin-targeting miR-542-3p overcomes HER3 signaling-induced chemoresistance and enhances the antitumor activity of paclitaxel against HER2-overexpressing breast cancer. Cancer letters, 420, 97-108.
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2

In vivo miRNA Inhibitor and Mimic Delivery

Check if the same lab product or an alternative is used in the 5 most similar protocols
The miRIDIAN has-miR-203 and has-miR-542-3p specific inhibitors, mimics, and their negative controls were purchased from Thermo Scientific Dharmacon (Lafayette, CO). In vivo-jetPEI®in vivo DNA and siRNA delivery reagent was purchased from Polyplus-transfection® SA (New York, NY). The Akt inhibitor VIII was purchased from EMD Chemicals, Inc. (Gibbstown, NJ). Paclitaxel (Ben Venue Labs, Inc., Bedford, OH) was obtained from University of Colorado Hospital pharmacy. The fully human anti-HER3 antibody MM-121 was kindly provided by Merrimack Pharmaceuticals Inc. (Cambridge, MA).
The primary antibodies used for western blot analyses were obtained as follows: Survivin (6E4) (Abcam, Cambridge, MA); Mcl-1 (Santa Cruz Biotechnology, Inc., Dallas, TX); Bcl-xl, caspase-8 (1C12), caspase-3 (8G10), and PARP (Cell Signaling Technology, Inc., Beverly, MA); β-actin (AC-75, Sigma-Aldrich, St. Louis, MO). All other reagents were purchased from Sigma-Aldrich unless otherwise specified.
Lyu H., Wang S., Huang J., Wang B., He Z, & Liu B. (2018). Survivin-targeting miR-542-3p overcomes HER3 signaling-induced chemoresistance and enhances the antitumor activity of paclitaxel against HER2-overexpressing breast cancer. Cancer letters, 420, 97-108.
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3

Modulating miR-346 and ATV in Cancer

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The miR-346 mimics, control mimics, miR-346 inhibitors, and control inhibitors were all purchased from Bioneer (Daejeon, Korea). In vivo-jetPEI®in vivo DNA and siRNA delivery reagent was purchased from Polyplus-transfection® SA (Polyplus, New York, NY) and lipofectamine (Thermo Fishers Scientific, Eugene, OR, USA). The primary antibodies used for western blot analyses were obtained as follows: Anti-HIF1alpha (BD Transduction Laboratories, San Jose, CA, USA); anti-VEGF, anti-cyclin B, anti-β-actin (Santa Cruz Biotechnology, Dallas, TX, USA); anti-cleaved PARP, anti-caspase-3, anti-p-cdc2 (Cell Signaling Technology Danvers, MA, USA); and anti-γ- H2AX (Millipore, Billerica, MA, USA). ATV was purchased from Sigma-Aldrich (St. Louis, MO, USA).
Kim E.H., Ko H.Y., Yu A.R., Kim H., Zaheer J., Kang H.J., Lim Y.C., Cho K.D., Joo H.Y., Kang M.K., Lee J.J., Lee S.S., Kang H.J., Lim S.M, & Kim J.S. (2020). Inhibition of HIF-1α by Atorvastatin During 131I-RTX Therapy in Burkitt’s Lymphoma Model. Cancers, 12(5), 1203.
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