Magnetom avanto fit 1.5 t, by Siemens - Product details

1

Pelvic MRI Tumor Segmentation Protocol

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Initial MRI data of the pelvic region were available for 71 out of the total 75 patients included in this study. All MRI examinations featured 1.5-Tesla 3D T2-weighted (T2W) contrast sequences, which were utilized for precise tumor delineation. MRI were acquired at eight institutions, using the following scanner models: Siemens Magnetom Avanto Fit 1.5 T, Siemens Magnetom Symphony TIM 1.5 T, and Hitachi Echelon 1.5 T. To minimize the effect of using different scanners, voxel intensities within tumor volumes of interest were normalized by the z-score method prior to radiomics analysis.
Intra-observer reproducibility was assessed by comparing two segmentations performed by the same observer (M.M.), 8 weeks apart to reduce recall bias. The similarity between segmentations was estimated using the dice similarity coefficient (DSC), calculated with a 3D Slicer (version 5.4.0). The mean (±standard deviation) intra-observer DSC was 0.936 ± 0.029 (range: 0.872–0.970). The mean (±standard deviation) intra-observer average Hausdorff distance was 0.50 ± 0.04 mm (range: 0.11–1.39).

Marinkovic M., Stojanovic-Rundic S., Stanojevic A., Tomasevic A., Jankovic R., Zoidakis J., Castellví-Bel S., Fijneman R.J., Cavic M, & Radulovic M. (2024). Performance and Dimensionality of Pretreatment MRI Radiomics in Rectal Carcinoma Chemoradiotherapy Prediction. Journal of Clinical Medicine, 13(2), 421.

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2

GRASP MRI Protocol for Brain Imaging

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GRASP MRI was performed using MAGNETOM Avanto FIT 1.5 T, MAGNETOM Skyra 3 T, and MAGNETOM Skyra FIT 3 T scanners (Siemens Healthineers, Erlangen, Germany) utilizing 20-channel head/neck coils. All patients were prepared in the scanner in a supine position. The conventional exam protocol consisted of an axial T1-weighted (T1w) TSE sequence (slice thickness ST = 4 mm), axial and coronal T2w FS/TIRM sequences (ST = 4 mm), and DWI acquisition. Sensitizing diffusion gradients were applied sequentially in the x, y, and z direction with b-values set to 0 and 1000 s/mm². Contrast-enhanced sequences included a dynamic GRASP acquisition with simultaneous contrast injection (injection speed 2.0 ml/s via 20G IV catheter, injection delay 20s, total dynamic acquisition time 4:23 min, 1.5 mm isotropic resolution), and an axial and coronal T1w FS post-contrast sequence (ST = 4 mm, Fig. 1). GRASP-specific sequence parameters are presented in Table 1.

Demerath T., Blackham K., Anastasopoulos C., Block K.T., Stieltjes B, & Schubert T. (2020). Golden-Angle Radial Sparse Parallel (GRASP) MRI differentiates head & neck paragangliomas from schwannomas. Magnetic resonance imaging, 70, 73-80.

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MRI Assessment of Cerebrovascular Changes

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All participants were scanned using a 1.5 T MRI scanner (Ingenia 1.5 T, Philips; Magnetom Avanto fit 1.5 T, Siemens). Images were assessed by two board-certified neurologists (T.H. and K.I.) for the presence of periventricular hyperintensity (PVH), deep white matter hyperintensity (DWMH), and cerebral microbleeds (CMBs), according to the published definition
¹²⁾. PVH and DWMH were rated using the Fazekas scale (0-3 for each hemisphere) on fluid-attenuated inversion recovery images. The CMBs were small (generally 2-5 mm in diameter, but occasionally up to 10 mm) areas devoid of signal, with associated blooming seen on T2^＊-weighted MRI. The CMBs were assessed for the number of lesions and the location (i.e., lobar, basal ganglia, or both).

Hoshino T., Ishizuka K., Toi S., Seki M, & Kitagawa K. (2021). Effects of Pemafibrate in Patients with Stroke and Hypertriglyceridemia: Baseline Cerebral Artery Diseases and 3-Month Laboratory Outcomes. Journal of Atherosclerosis and Thrombosis, 29(7), 1020-1030.

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Carotid and Intracranial Artery Assessment

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Carotid ultrasound was performed on all patients according to standard procedures
¹⁰⁾, using a high-resolution B-mode ultrasound system (Nemio SSA-550A, Toshiba) with a 7.5-MHz transducer by trained ultrasonographers who were blinded to the purpose of this study. The intima-media thickness (IMT) of the far wall was electronically measured on both sides of the common carotid artery, carotid artery bulb, and internal carotid artery. Plaques were included in the IMT measurements. We used the mean of the right and left maximum IMTs at the three locations. We defined significant extracranial artery stenosis (ECAS) as the presence of atherosclerotic stenosis of ≥ 50% or occlusion according to the European Carotid Surgery Trial criteria
¹¹⁾.
Intracranial arteries were examined using time-of-flight MRA using a 1.5 T MRI scanner (Ingenia 1.5 T, Philips; Magnetom Avanto fit 1.5 T, Siemens). The narrowest diameter of each stenosed vessel was measured and divided by the diameter of the normal vessel proximal to the lesion or distal to the lesion if the proximal artery was diseased. Significant intracranial artery stenosis (ICAS) was defined as ≥ 50% stenosis or occlusion. The location of ICAS was divided into anterior (i.e., internal carotid, middle cerebral, and anterior cerebral arteries) and posterior (i.e., vertebral, basilar, and posterior cerebral arteries) circulation.

Hoshino T., Ishizuka K., Toi S., Seki M, & Kitagawa K. (2021). Effects of Pemafibrate in Patients with Stroke and Hypertriglyceridemia: Baseline Cerebral Artery Diseases and 3-Month Laboratory Outcomes. Journal of Atherosclerosis and Thrombosis, 29(7), 1020-1030.

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Shoulder Motion in Healthy Adults

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After obtaining informed consent (IRB 71782), ten healthy subjects <35 years of age and ten healthy subjects >45 years of age participated in a study of shoulder motion. These age groups were motivated by the relative distribution of shoulder injury and pathology described previously. Subjects recruited from the University of Utah were in good health (no preconditions on activity level), BMI ≤30, with equal distribution of sex per group. Subjects were screened for gross shoulder abnormalities and any history of shoulder surgery or pain. After pre-screening, anteroposterior and axillary radiographs were obtained to examine parameters like joint congruency and spacing. Magnetic resonance imaging followed standard shoulder protocols for our institution (e.g. axial PD FS; coronal T1, T2 FS; sagittal T1, T2 FS, oblique T2 FS; 320×320 or 384×384 matrix; 3.5/3.8 mm or 5.0/5.5 mm slices; no contrast; Magnetom Avanto_Fit 1.5T, Siemens, Malvern, PA). A fellowship-trained, board-certified orthopedic shoulder surgeon (PNC or RZT) reviewed radiographic and magnetic resonance imaging for signs of pathology. Subjects determined to have asymptomatic pathology (e.g. rotator cuff tears, osteoarthritis) were excluded from further study.”

Kolz C.W., Sulkar H.J., Aliaj K., Tashjian R.Z., Chalmers P.N., Qiu Y., Zhang Y., Foreman K.B., Anderson A.E, & Henninger H.B. (2021). Age-related differences in humerothoracic, scapulothoracic, and glenohumeral kinematics during elevation and rotation motions. Journal of biomechanics, 117, 110266.

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Shoulder Motion in Healthy Adults

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After obtaining informed consent (IRB 71782), ten healthy subjects <35 years of age and ten healthy subjects >45 years of age participated in a study of shoulder motion. These age groups were motivated by the relative distribution of shoulder injury and pathology described previously. Subjects recruited from the University of Utah were in good health (no preconditions on activity level), BMI ≤30, with equal distribution of sex per group. Subjects were screened for gross shoulder abnormalities and any history of shoulder surgery or pain. After pre-screening, anteroposterior and axillary radiographs were obtained to examine parameters like joint congruency and spacing. Magnetic resonance imaging followed standard shoulder protocols for our institution (e.g. axial PD FS; coronal T1, T2 FS; sagittal T1, T2 FS, oblique T2 FS; 320×320 or 384×384 matrix; 3.5/3.8 mm or 5.0/5.5 mm slices; no contrast; Magnetom Avanto_Fit 1.5T, Siemens, Malvern, PA). A fellowship-trained, board-certified orthopedic shoulder surgeon (PNC or RZT) reviewed radiographic and magnetic resonance imaging for signs of pathology. Subjects determined to have asymptomatic pathology (e.g. rotator cuff tears, osteoarthritis) were excluded from further study.”

Kolz C.W., Sulkar H.J., Aliaj K., Tashjian R.Z., Chalmers P.N., Qiu Y., Zhang Y., Foreman K.B., Anderson A.E, & Henninger H.B. (2021). Age-related differences in humerothoracic, scapulothoracic, and glenohumeral kinematics during elevation and rotation motions. Journal of biomechanics, 117, 110266.

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6 protocols using magnetom avanto fit 1.5 t

Pelvic MRI Tumor Segmentation Protocol

GRASP MRI Protocol for Brain Imaging

MRI Assessment of Cerebrovascular Changes

Carotid and Intracranial Artery Assessment

Shoulder Motion in Healthy Adults

Shoulder Motion in Healthy Adults

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