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Antibodies to type 1 collagen and fibronectin

Manufactured by Santa Cruz Biotechnology
Sourced in United States

Antibodies to type I collagen and fibronectin are laboratory reagents used for the detection and analysis of these extracellular matrix proteins. Type I collagen is a major structural component of connective tissues, while fibronectin plays a role in cell adhesion and migration. These antibodies can be utilized in various experimental techniques, such as immunohistochemistry, Western blotting, and ELISA, to identify and quantify the presence of these proteins in biological samples.

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2 protocols using antibodies to type 1 collagen and fibronectin

1

Molecular Mechanisms of Fibrosis Regulation

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Antibodies to p‐PDGFR‐β, p‐VEGFR2, p‐Src, Src, p‐STAT3, STAT3, p‐Smad3, Smad3, TGF‐β1, p‐NF‐κBp65, p‐Akt, Akt and β‐Actin were purchased from Cell Signaling Technology. TGF‐β1 and antibodies to type I collagen and fibronectin were purchased from Santa Cruz Biotechnology. p‐FGFR1 antibody was purchased from Life Span Biosciences. NF‐κBp65 antibody was purchased from Prosci Inc. Antibodies to CD68, CD31, MMP‐2, TIMP‐2, E‐cadherin, vimentin, Snail, Twist, and MCP‐1, TNF‐α, IL‐1β and IL‐6 ELISA assay kits were purchased from Abcam Inc. Nintedanib was purchased from Cayman. α‐SMA antibody, CG, Cell Counting Kit‐8 (CCK‐8) proliferation assay kit and all other chemicals were purchased from Sigma.
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2

Molecular Mechanisms of Pulmonary Fibrosis

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Antibodies to type I collagen and fibronectin were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Antibodies to α-SMA, CD31, MMP-2, TIMP-2, E-cadherin, β-vimentin, Snail, Twist, MCP-1, TNF-α, interleukin-1β (IL-1β), IL-6, and ELISA assay kits were purchased from Abcam Inc (Cambridge, UK). Antibodies to p-STAT3, STAT3, p-Smad3, Smad3, p-NF-κB, NF-κB, and β-actin were purchased from Cell Signaling Technology (Danvers, MA, USA). Antibody to CD68 was purchased from Servicebio (Wuhan, China). Nintedanib was purchased from Cayman (Arbor, MI, USA). CG and all other chemicals were purchased from Sigma (St. Louis, MO, USA).
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