Reagents: unless otherwise indicated, all solvents and organic reagents were obtained from commercially available sources and were used without further purification. Acetone was dried by a molecular sieve. Potassium iodate (99%, Innochem) was used in this oxidative reaction.
Instrument: The reaction process was monitored by thin-layer chromatography (TLC, Yantai Jiangyou Co.Ltd, Tsingdao, Shandong, China) with silica gel plates (thickness = 0.20 mm, GF254) under UV light and LC-MS (Waters Acquity UPLC/SQD, Waters Acquity UPLC/SQD, Milford, MA, USA). Mass spectra were obtained using a Waters Acquity UPLC-SQD mass spectrometer. High-resolution mass spectra (HRMS, Thermo Scientific Exactive. Plus, 81 Wyman Street, Waltham, MA, USA) were recorded on an Agilent Technologies LC/MSD TOF spectrometer. The 1H-NMR spectra were recorded on a Varian Mercury 400 or 500 MHz instrument, and 13C-NMR spectra were recorded at 400 or 500 MHz on a Varian Mercury using dimethyl sulfoxide-d6 (DMSO-d6), methanol-d4 (CD3OD), chloroform-d (CDCl3) as the solvents and tetramethylsilane (TMS) as an internal standard.
Instrument: The reaction process was monitored by thin-layer chromatography (TLC, Yantai Jiangyou Co.Ltd, Tsingdao, Shandong, China) with silica gel plates (thickness = 0.20 mm, GF254) under UV light and LC-MS (Waters Acquity UPLC/SQD, Waters Acquity UPLC/SQD, Milford, MA, USA). Mass spectra were obtained using a Waters Acquity UPLC-SQD mass spectrometer. High-resolution mass spectra (HRMS, Thermo Scientific Exactive. Plus, 81 Wyman Street, Waltham, MA, USA) were recorded on an Agilent Technologies LC/MSD TOF spectrometer. The 1H-NMR spectra were recorded on a Varian Mercury 400 or 500 MHz instrument, and 13C-NMR spectra were recorded at 400 or 500 MHz on a Varian Mercury using dimethyl sulfoxide-d6 (DMSO-d6), methanol-d4 (CD3OD), chloroform-d (CDCl3) as the solvents and tetramethylsilane (TMS) as an internal standard.