Quercetin particle imaging was obtained using a NaioAFM atomic force microscope (Nanosurf, Switzerland). We made three different measurements of its length using the Naio software (Nanosurf, Switzerland) and calculated the average particle size.
Naio software
Manufactured by Nanosurf
Sourced in Switzerland
Naio is a software package developed by Nanosurf for the analysis and processing of data acquired with Nanosurf's scanning probe microscopes. It provides basic functionalities for image visualization, processing, and measurement.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using naio software
1
Quercetin Particle Size Analysis
2
Topographic and Phase Imaging of Solid Dispersions
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The NaioAFM (Nanosurf, Switzerland) instrument was used to obtain topographic and phase images, allowing calculation of the surface roughness of the solid dispersions. Samples of extrudate were softened immediately after HME between two flat glass slides and then cooled on metal block. The slides were then carefully removed, and the solid sample was placed on the sample holder. Both topographic and phase images were generated with the instrument operating in dynamic mode using a Tap 190Al-G cantilever (BudgetSensors, Bulgaria). Image sizes were 10x10 µm or 25x25 µm, taken at a speed of 0.8 seconds per line. Additional parameters were varied depending on each sample and optimum sensitivity. The setpoint of the cantilever was varied from 50% to 60% of the free vibrational amplitude, which was varied from 200-1000 mV. Nanosurf Naio software was used to control, obtain the data and Image J was used to further analyse the images.
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