1 2 5 dimethoxy 4 iodophenyl 2 aminopropane hydrochloride

Manufactured by Merck Group

Sourced in Italy

(±)-1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride is a chemical compound used as a research tool in laboratory settings. It is a racemic mixture of two enantiomers. The compound's core function is to serve as a research tool, without further interpretation or extrapolation on its intended use.

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Lab products found in correlation

2 5 dimethoxy 4 iodoamphetamine hydrochloride, by Merck Group (2 mentions) Ketamine, by Merck Group (1 mentions) Trazodone, by Merck Group (1 mentions) Ly379268, by Bio-Techne (1 mentions) 2 3 3h d aspartate, by PerkinElmer (1 mentions) Penicillin streptomycin, by Thermo Fisher Scientific (1 mentions) Insulin transferrin selenium, by Thermo Fisher Scientific (1 mentions) Tunel kit, by Merck Group (1 mentions) Bovine serum albumin (bsa), by Thermo Fisher Scientific (1 mentions) Ritanserin, by Merck Group (1 mentions) Cell death elisa kit, by Roche (1 mentions)

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Hydrochlorides (2 citations)

2 protocols using 1 2 5 dimethoxy 4 iodophenyl 2 aminopropane hydrochloride

Radiolabeled Aspartate Binding Assay

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[2,3-³H]D-aspartate (specific activity 11.3 Ci/mmol) was from Perkin Elmer (NET581001MC, Boston, MA, USA). LY379268 was purchased from Tocris Bioscience (2453, Bristol, UK). (±)-1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride, (±)-2,5-Dimethoxy-4-iodoamphetamine hydrochloride [(±) DOI], MDL11,939, ketamine, and trazodone were purchased from Sigma (Milan, Italy).

Taddeucci A., Olivero G., Roggeri A., Milanese C., Giorgio F.P., Grilli M., Marchi M., Garrone B, & Pittaluga A. (2022). Presynaptic 5-HT2A-mGlu2/3 Receptor–Receptor Crosstalk in the Prefrontal Cortex: Metamodulation of Glutamate Exocytosis. Cells, 11(19), 3035.

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Neural Stem Cell Culture and Analysis

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The sources of reagents are listed below. Dulbecco’s modified Eagle Medium (DMEM)/Ham’s F12 and F15 medium, Insulin-Transferrin-Selenium, 7.5% bovine serum albumin, platelet derived growth factor (PDGF)-AA, basic fibroblast growth factor (bFGF), penicillin/streptomycin, 2.5% trypsin, neurobasal medium (NBM) and B27 supplement: Invitrogen (Carlsbad, CA). Ciliary neurotrophin factor (CNTF), progesterone, triiodothyronine, biotin, putrescine, cysteine, hydrocortisone, and 5-HT2 receptor agonist 1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride, (±)-2,5-Dimethoxy-4-iodoamphetamine hydrochloride (DOI), 5-HT2A receptor antagonist, ritanserin: Sigma (St. Louis, MO). Terminal deoxynucleotidyl transferase mediated dUTP Nick End Labeling (TUNEL) kit: Millipore (Billerica, MA). Cell Death ELISA kit: Roche (Indianapolis, IN). Antibodies used in this study are listed in table 1.

Fan L.W., Bhatt A., Tien L.T., Zheng B., Simpson K.L., Lin R.C., Cai Z., Kumar P, & Pang Y. (2015). Exposure to serotonin adversely affects oligodendrocyte development and myelination in vitro. Journal of neurochemistry, 133(4), 532-543.

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