Mouse anti drp1

Manufactured by Santa Cruz Biotechnology

Sourced in United States

Mouse anti-Drp1 is an antibody product that specifically binds to the Dynamin-related protein 1 (Drp1) antigen. Drp1 is a GTPase involved in mitochondrial fission. The antibody can be used to detect and study the expression and localization of Drp1 in biological samples.

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Lab products found in correlation

Mouse anti β actin antibody, by Merck Group (1 mentions) Rabbit anti egfr, by Santa Cruz Biotechnology (1 mentions) Rabbit anti mfn 1, by Santa Cruz Biotechnology (1 mentions) Mouse anti mtco1, by Abcam (1 mentions) Anti rabbit egfr, by Abcam (1 mentions) Mouse anti vinculin, by Santa Cruz Biotechnology (1 mentions) Mouse anti opa1, by BD (1 mentions) Rabbit anti tom20, by Santa Cruz Biotechnology (1 mentions) Rabbit anti kif5b, by Abcam (1 mentions) Alexa fluor 488 goat anti rabbit, by Thermo Fisher Scientific (1 mentions)

Close spelling variants of this product

Anti-Drp1 (28 citations)

2 protocols using mouse anti drp1

Antibody Characterization for EGFR Signaling

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The primary antibodies used for immunoblot analysis and immunohistochemical staining were rabbit anti-EGFR, mouse anti-vinculin, mouse anti-Tom23, goat anti-Tim23, rabbit anti-Mfn1, mouse anti-Drp1 (all above from Santa Cruz Biotechnology, CA, USA), mouse anti-MTCO1 (Abcam, Cambridge, UK), rabbit anti-phospho-EGFR (Tyr1068), rabbit anti- phospho-Drp1 (Ser637) (all above from Cell Signaling Technology, Inc., MA, USA), mouse anti-OPA1 (BD Biosciences, NJ, USA) and mouse anti-myc, mouse anti-Flag, mouse anti-β actin antibody (all above from Sigma-Aldrich, Inc., MO, USA). The primary antibodies used for immnofluorescence staining were rabbit anti-EGFR (Abcam, Cambridge, UK) antibody.

Che T.F., Lin C.W., Wu Y.Y., Chen Y.J., Han C.L., Chang Y.L., Wu C.T., Hsiao T.H., Hong T.M, & Yang P.C. (2015). Mitochondrial translocation of EGFR regulates mitochondria dynamics and promotes metastasis in NSCLC. Oncotarget, 6(35), 37349-37366.

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Immunostaining and Western Blotting Analysis

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For immunostaining and Western blotting analysis, sources of antibodies are as follows: mouse anti-ACTB/β-actin (Sigma-Aldrich, A1978), mouse anti-DRP1 (Santa Cruz Biotechnology, sc-271583), rabbit anti-p-ser616-DRP1 (Cell Signaling Technology, 3455), rabbit anti-MFN1 (Thermo Fisher Scientific, PA5–38042), mouse anti-MFN2 (Santa Cruz, sc-100560), rabbit anti-VPS35 (Novus Biologicals, 13517), mouse anti-TUBA/α tubulin (Abcam, ab7291), mouse anti-acetyl-K40-TUBA/α tubulin (Abcam, ab24610), mouse anti-TU-20/ β-tubulin (Cell Signaling Technology, 4466), rabbit anti-DCTN1/dynactin p150Glued (Cell Signaling Technology, 69399), rabbit anti-KIF5B (Abcam, ab167429), rabbit anti-Tom20 (Santa Cruz Biotechnology, sc-11415), and Alexa Fluor 488 or 555-conjugated secondary antibodies (Thermo Fisher Scientific, Alexa Fluor 488 goat anti-rabbit, A-11008; Alexa Fluor 555 goat anti-mouse, A-21422).

Morcillo P., Cordero H., Ijomone O.M., Ayodele A., Bornhorst J., Gunther L., Macaluso F.P., Bowman A.B, & Aschner M. (2021). Defective Mitochondrial Dynamics Underlie Manganese-Induced Neurotoxicity. Molecular neurobiology, 58(7), 3270-3289.

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