FDG PET/CT images were acquired in all 20 patients, using a Gemini TF scanner (Philips Healthcare, Cleveland, OH, USA) before and during RT. The timing of scanning during RT ranged from the 3rd to 4th week of RT (median, 26 days from the start of RT). The PET/CT scanning methods used were as previously described [14 (link)]. The acquired PET/CT images were transferred to a dedicated workstation and analyzed using the vendor-provided software (The Extended Brilliance Workspace with Fusion Viewer, Philips Healthcare). The software of the workstation provided automatically delineated volume-of-interest (VOI) over the tumor using a threshold of 50% of maximum standardized uptake value (SUVmax) [15 (link)]. Metabolic tumor volume (MTV) was defined as those voxels having an SUV greater than 50% of the SUVmax. Total lesion glycolysis (TLG) was calculated by multiplying MTV by the mean standardized uptake value (SUVmean). SUV, MTV, and TLG were measured at the primary tumor site. There were 3 patients whose metabolic parameters were unmeasurable at the primary tumor site after neoadjuvant chemotherapy, and their PET/CT parameters were measured at the metastatic nodal sites. If the tumor could not be distinguished from the background, MTV was set as a single voxel with a volume of 0.1 cm3. SUV was assigned with a default value of 1.0, which was the minimum value [16 (link)].
Gemini tf scanner
Manufactured by Philips
Sourced in United States
The Gemini TF scanner is a high-performance computed tomography (CT) scanner designed for medical imaging applications. It features advanced technology to provide detailed and accurate imaging data for diagnostic purposes.
Automatically generated - may contain errors
7 protocols using gemini tf scanner
1
PET/CT Imaging Protocol for Tumor Metabolic Analysis
2
PET-CT Imaging Protocol for FDG Uptake
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
All patients underwent PET–CT using integrated PET–CT scanners (Biograph Truepoint or mCT40, Siemens Healthineers; Gemini TF scanner, Philips Healthcare; Discovery STE, General Electric Healthcare). Patients fasted for at least 6 h, and FDG (5.18 MBq/kg) was administered intravenously. Images were acquired approximately 60 min after injection. Patients were examined in the supine position with the arm down. A CT scan (40 mA and 120 kVp) was performed for attenuation correction without contrast enhancement, and PET images were acquired from the skull base to the toe. The CT images were reconstructed using a 512 × 512 matrix in combination with a 50-cm field of view and a 3-mm slice thickness.
3
Standardized PET/CT Imaging Protocol
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
All patients underwent whole-body PET/CT acquisition 60 ± 10 min after injection 18F-FDG by 3.7 MBq/kg. Prior to FDG injection, all patients fasted for at least 6 h. In all cases, the serum glucose concentration met the institutional requirement (≤120 mg/dL).
PET/CT scans were conducted by a Siemens Biograph mCT Flow 64 scanner (Siemens, Erlangen, Germany) or Gemini TF scanner (Philips Medical Systems, The Netherlands) which covered the length from the top of skull to the mid-thigh. A low-dose CT scan (120 kV, 35 mA, slice 3 mm) was first performed, and PET acquisition speed was 1.5 mm/s (slice 3 mm, filter: Gaussian, FWHM: 5 mm) or scanning at a total of 9–10 bed positions, a 90-s acquisition time for each bed position. A Siemens Biograph mCT Flow 64 scanner PET images were reconstructed using a three-dimensional iterative reconstruction with the time-of-flight algorithm, and the low-dose CT scans were acquired in CARE Dose 4D mode. A Gemini TF scanner PET reconstruction parameters included use of 3D model, and use of ordered-subcohorts expectation maximization(OSEM) method (two iterations, four subcohorts, 128×128 pixels of 5.15 mm). Attenuation corrections of the PET images were performed using data from CT imaging.
PET/CT scans were conducted by a Siemens Biograph mCT Flow 64 scanner (Siemens, Erlangen, Germany) or Gemini TF scanner (Philips Medical Systems, The Netherlands) which covered the length from the top of skull to the mid-thigh. A low-dose CT scan (120 kV, 35 mA, slice 3 mm) was first performed, and PET acquisition speed was 1.5 mm/s (slice 3 mm, filter: Gaussian, FWHM: 5 mm) or scanning at a total of 9–10 bed positions, a 90-s acquisition time for each bed position. A Siemens Biograph mCT Flow 64 scanner PET images were reconstructed using a three-dimensional iterative reconstruction with the time-of-flight algorithm, and the low-dose CT scans were acquired in CARE Dose 4D mode. A Gemini TF scanner PET reconstruction parameters included use of 3D model, and use of ordered-subcohorts expectation maximization(OSEM) method (two iterations, four subcohorts, 128×128 pixels of 5.15 mm). Attenuation corrections of the PET images were performed using data from CT imaging.
4
Multisite PET/CT Clinical Protocols
5
FDG PET-CT Imaging Protocol for Head and Neck
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
FDG PET-CT images were acquired using a Gemini TF scanner (Philips, Bel Air, MD, USA). Patients were prepared according to European Association of Nuclear Medicine (EANM) guidelines and had to fast for 6 h prior to FDG administration. For patients with diabetes mellitus, the plasma glucose level was required to be <10 mmol/L. A dose between 190 and 240 MBq [18F]-fluorodeoxyglucose (FDG) was administered depending on body mass index (BMI). PET images of head and neck were acquired at 3 min per bed position with a total field of view (FOV) of 576 mm (three bed positions), and reconstructed to 2 mm isotropic voxels using a BLOB-OS algorithm including time-of-flight information. For anatomical orientation and attenuation correction, low-dose CT was acquired with 40 mAs and a slice thickness of 2 mm. All FDG PET/CT images were assessed by dedicated nuclear medicine radiologists in the clinical setting; these reports were used for this study.
6
Retrospective PET Analysis of Lung Lesions
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
In addition to phantom measurements, PET data of 65 patients with confirmed lung lesions were retrospectively analyzed. Histological categorization of these tumors fell beyond our scope since focus was on the limitations of PET imaging. Patients fasted for at least 6 hours before the intravenous administration of 350–400 MBq of 18F-FDG. Blood glucose levels were always under 12 mmol/l. All patients were examined on the Philips Gemini TF scanner. Emission scans began 60 min after injection. Acquisition duration was 60–150 seconds per bed position, depending upon the patient weight. Delineation of lesion volumes was carried out by isocontouring with threshold at SUV = 2.5 g/cm3. Low dose CT scans were carried out without oral or intravenous administration of contrast agent. The study was approved by the local ethics committee (Regional And Institutional Ethics Committee, Clinical Center, University Of Debrecen). As the whole patient related data was a retrospectively analyzed, informed consent was not obtained.
7
Multitracer PET/CT Imaging in Patients
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
The Committee for the Protection of People "Ile-de-France V" approved this retrospective study, and the requirement to obtain informed consent was waived.
PET/CT scans were acquired over the full body (from vertex to toes) with different PET tracers ( 18 F-FDG, 18 F-fluoride, 18 F-fluoroDOPA, and 68 Ga-DOTATOC) in patients older than 18 y from November 1, 2012, to October 31, 2013, at the nuclear medicine department of Hôpital Tenon in Paris. All examinations were performed on a GEMINI TF scanner (Philips) with a 16-slice CT component. The acquisition parameters for the low-dose CT were 120 kVp and 76-80 mAs (adapted to 100-120 mAs for some obese patients). The pixel size was 1.172 • 1.172 mm 2 (or voxels of 3.433 mm 3 for a slice thickness of 2.5 mm) or, when the field of view was enlarged for obese people, 1.367 • 1.367 mm 2 (or voxels of 4.673 mm 3 for a slice thickness of 2.5 mm).
PET/CT scans were acquired over the full body (from vertex to toes) with different PET tracers ( 18 F-FDG, 18 F-fluoride, 18 F-fluoroDOPA, and 68 Ga-DOTATOC) in patients older than 18 y from November 1, 2012, to October 31, 2013, at the nuclear medicine department of Hôpital Tenon in Paris. All examinations were performed on a GEMINI TF scanner (Philips) with a 16-slice CT component. The acquisition parameters for the low-dose CT were 120 kVp and 76-80 mAs (adapted to 100-120 mAs for some obese patients). The pixel size was 1.172 • 1.172 mm 2 (or voxels of 3.433 mm 3 for a slice thickness of 2.5 mm) or, when the field of view was enlarged for obese people, 1.367 • 1.367 mm 2 (or voxels of 4.673 mm 3 for a slice thickness of 2.5 mm).
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!