2 n morpholino ethane sulfonic acid mes

PLGA (lactide/glycolide =50:50, molecular weight =94,000 Da) was purchased from Daigang Biomaterial Co., Ltd. (Jinan, People’s Republic of China). Chloroauric acid (HAuCl₄) was obtained from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, People’s Republic of China). CTAB was obtained from Dibo Ltd. (Shanghai, People’s Republic of China). Ascorbic acid (AA), sodium borohydride (NaBH₄), and silver nitrate (AgNO₃) were purchased from Guobang Pharmaceutical Company (Shanxi, People’s Republic of China). GSH (purity >98%) was obtained from Genview Co., Ltd. (Beijing, People’s Republic of China). DTX was obtained from Meilun Biotechnological Company (Dalian, People’s Republic of China). Poly(vinyl alcohol) (PVA) was obtained from Kelong Chemical Reagent Company (Chengdu, People’s Republic of China). Both potassium permanganate (KMnO₄) and 2-(N-morpholino) ethane-sulfonic acid (MES) were purchased from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, People’s Republic of China). The Michigan Cancer Foundation – 7 (MCF-7) human breast cancer cell line was purchased commercially from the Cell Bank of the Chinese Academy of Sciences (Catalog No TCHu 74; Shanghai, People’s Republic of China). All the other chemicals were obtained from Sigma-Aldrich Co. Ltd (St Louis, MO, USA).

Glutathione (GSH), citric acid, 2-(N-morpholino)ethanesulfonic acid (MES) and different kinds of amino acids were purchased from Sinopharm Chemical Reagent Co., Ltd (Shanghai, China). Dialysis membrane (MWCO = 1000) were from Spectrumlabs (America). Human serum samples were provided by healthy volunteer from Hospital of Xinyang Normal University. Human urine samples were provided by healthy volunteer in our research group.