Nimodipine was purchased from Kangmanlin Chemical Industry Co., Ltd (Nanjing, China). Nitrendipine, used as an internal standard, was purchased from the National Institute of Food and Drug Control (Beijing, China). Twenty percent (w/w) aqueous injectable emulsion (long-chain oil: medium-chain oil, 1:1, w/w) was purchased from Baxter Qiaoguang Healthcare Co., Ltd (Guangzhou, China). Nimotop injection (10 mg/50 mL) was purchased from Bayer Pharma AG. PEG400 was obtained from Well Chemical Co., Ltd (Nanjing, China). Five percent glucose solution injection and 0.9% sodium chloride injection were purchased from Tianrui Pharmaceutical Co., Ltd (Zhejiang, China). Two percent 2,3,5-triphenyl tetrazolium chloride, 4% paraformaldehyde solution, and 10% paraformaldehyde were purchased from Yuanye Biotechnology Co., Ltd (Shanghai, China). Heparin sodium salt, chloral hydrate, diethyl ether, and n-hexane were of AR grade and were purchased from Sinopharm Chemical Reagent Co., Ltd. Methanol (HPLC grade) and acetonitrile (HPLC grade) were purchased from Thermo Fisher (China) Co., Ltd. All other chemical reagents were of analytical grade or chromatographic grade.
Heparin sodium salt
Manufactured by Sinopharm
Sourced in China
Heparin sodium salt is a laboratory reagent used as an anticoagulant. It is a naturally occurring substance derived from animal tissue, primarily porcine intestinal mucosa. Heparin sodium salt inhibits the activity of thrombin and other enzymes involved in the blood coagulation cascade, preventing the formation of blood clots.
Automatically generated - may contain errors
Lab products found in correlation
Paraformaldehyde solution, by Yuanye Bio-Technology (1 mentions)
Paraformaldehyde (pfa), by Yuanye Bio-Technology (1 mentions)
Hplc grade methanol, by Thermo Fisher Scientific (1 mentions)
Hplc grade acetonitrile, by Thermo Fisher Scientific (1 mentions)
Chloral hydrate, by Sinopharm (1 mentions)
N hexane, by Sinopharm (1 mentions)
Diethyl ether, by Sinopharm (1 mentions)
Mcf 7, by National Collection of Authenticated Cell Cultures (1 mentions)
Doxorubicin hydrochloride dox, by Sangon (1 mentions)
Lambda 950 uv vis nir spectrometer, by PerkinElmer (1 mentions)
Hydrogen peroxide, by Merck Group (1 mentions)
Trypsin, by Thermo Fisher Scientific (1 mentions)
Hematoxylin and eosin h e staining kit, by Solarbio (1 mentions)
Alizarin red s staining kit, by Beyotime (1 mentions)
Collagenase type 2, by neoFroxx (1 mentions)
Alp staining, by Beyotime (1 mentions)
Human murine rat bmp 2 standard tmb elisa development kit, by Thermo Fisher Scientific (1 mentions)
4 6 diamidino 2 phenylindole (dapi), by Abcam (1 mentions)
Sodium β glycerophosphate, by Merck Group (1 mentions)
Cck 8 assay, by Apexbio (1 mentions)
4 protocols using heparin sodium salt
1
Nimodipine Formulation Development and Evaluation
2
Doxorubicin-Heparin Targeted Nanomedicine
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Doxorubicin hydrochloride (DOX) was purchased from Sangon Biotech Co., Ltd. (Shanghai, China). Heparin sodium salt (Mn=1.25 kDa, 189 U/mg) was obtained from Sinopharm Chemical Reagent Co. (Shanghai, China) and succinylated in our lab. Adipic dihydrazide (ADH), 1-ethyl-3,3-dimethylaminopropylcarbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) were purchased from Medpep Co. (Shanghai, China). Polyethylene glycol (PEG, MW 5069 Da) was synthesized by AppliChem Co. (Darmstadt, Germany). Cyclic RGD peptide (cRGD) was synthesized by Bohin biotechnology Co. Ltd. (Xiamen, China). Cyanine5.5 amine (Cy5.5) was purchased from Lumiprobe LLC (Florida, USA). Dialysis Membrane (MWCO 3,500) was obtained from Pharmacia (Piscataway, NJ, USA). Folate-NH2 and Biotin-NH2 were prepared in our laboratory. Biotinylated MBs were donated by the Department of Pharmacy (Nanfang Hospital, China). Human breast carcinoma cell line MCF-7 and lung cancer cell line A549 were obtained from the Chinese Academy of Sciences Cell Bank (Shanghai, China). All other chemicals and reagents were purchased from Sigma Co. (St. Louis, MO, USA).
3
Evaluation of Coagulation Assays on Microdevice
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APTT and PT test kits were purchased from Sun Biotech Co., Ltd., Shanghai, China. APTT test kits contained APTT activator (a mixture of cephalin and ellagic acid) and APTT starter (25 mM Calcium Chloride). Ethyl alcohol and hydrogen peroxide were bought from Sigma-Aldrich. Heparin sodium salt was purchased from Sinopharm Chemical Reagent Co., Ltd., Beijing, China. Parylene-C was purchased from Specialty Coating Systems, Indianapolis, IN, USA. 0.01 M phosphate buffer saline (PBS, PH7.2) was purchased from GE Healthcare Life Sciences. Dade Actin activated cephaloplastin and Thromborel-S reagents for the SYSMEX hemostasis system were purchased from SIEMENS Healthcare Diagnostics Products GmbH, Germany.
PDS 2010 chemical deposition system (Specialty Coating Systems, Indianapolis, IN, USA) was used to form parylene-C membrane on the QCM surface. Milli-Q academic filtration system (Merck KGaA, Darmstadt, Germany) was used to produce deionized water. An ultraviolet and visible spectrometer (UV/VIS/NIR Spectrometer Lambda 950, Perkin Elmer, Waltham, MA, USA) was used to perform APTT tests based on absorbance spectroscopy. A SYSMEX CS-5100 hemostasis system (Siemens Healthcare GmbH, Erlangen, Germany) was used to perform comparative tests of APTT and PT.
PDS 2010 chemical deposition system (Specialty Coating Systems, Indianapolis, IN, USA) was used to form parylene-C membrane on the QCM surface. Milli-Q academic filtration system (Merck KGaA, Darmstadt, Germany) was used to produce deionized water. An ultraviolet and visible spectrometer (UV/VIS/NIR Spectrometer Lambda 950, Perkin Elmer, Waltham, MA, USA) was used to perform APTT tests based on absorbance spectroscopy. A SYSMEX CS-5100 hemostasis system (Siemens Healthcare GmbH, Erlangen, Germany) was used to perform comparative tests of APTT and PT.
4
Biomimetic Hydrogel for Bone Regeneration
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Gelatin (porcine skin, type A), dopamine hydrochloride, 2-(dimethylamino)ethyl methacrylate (DMAEMA), polyethylene glycol diacrylate (PEGDA), visible light initiator lithium phenyl(2,4,6-trimethylbenzoyl) phosphinate (LAP), DCFH-DA, Hoechst 33342, β-sodium glycerophosphate, l -ascorbic acid and dexamethasone were purchased from Sigma Aldrich (St. Louis, MO, USA). Heparin sodium salt (Mn = 1.25 kDa, >189 U/mg, Sinopharm Chemical Reagent Co. Shanghai, China), 2, 2-diphenyl-1-picrylhydrazyl (DPPH) (Mackline, China), Recombinant Human/Murine/Rat BMP-2 (E.coli derived, PeproTech, USA), Human/Murine/Rat BMP-2 Standard TMB ELISA Development Kit (PeproTech, USA), Live/Dead Staining Kit (Beyotime, China), CCK8 assay (ApexBio, USA), fetal bovine serum (FBS; HyClone, USA), α-MEM (HyClone, USA), 1% penicillin-streptomycin solution (HyClone, USA), trypsin (Gibco, USA), type II collagenase (BioFroxx, Germany), DAPI (Abcam, USA), Alizarin Red S (ARS) Staining Kit (Beyotime, China), Alp staining (Beyotime, China), Hematoxylin and Eosin (H&E) Staining Kit (Solarbio, China) and Masson's Trichrome Stain Kit (Solarbio, China) were used for in vitro and in vivo study. Unless otherwise stated, all other regents and solvents were used as received without further purification or modification.
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