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Nh2 peg12 cooh tbu

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NH2-PEG12-COOH-tBu is a bifunctional polyethylene glycol (PEG) linker. It consists of a PEG chain with an amino group (NH2) at one end and a carboxylic acid group (COOH) at the other end, both protected with a tert-butyl (tBu) group. This linker can be used to conjugate molecules or compounds for various applications.

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Lab products found in correlation

Tyramine, by Merck Group (2 mentions) K2co3, by Merck Group (2 mentions) Ch2cl2, by Merck Group (2 mentions) Diisopropylethylamine dipea, by Merck Group (2 mentions) Pure coat amine 24 well microtiter plates, by BD (2 mentions) Cf3cooh, by Merck Group (2 mentions) N n dimethylformamide (dmf), by Merck Group (2 mentions) Methanol, by Merck Group (2 mentions) Dimethyl sulfoxide (dmso), by Merck Group (2 mentions) Sulfuric acid, by Merck Group (2 mentions) Piperidine, by Merck Group (2 mentions) Isopropyl alcohol, by Merck Group (2 mentions) 2 1h 7 azabenzotriazole 1 yl 1 1 3 3 tetramethyl uronium hexafluorophosphate methanaminium hatu, by GenScript (2 mentions) Protected amino acids, by Chem-Impex (1 mentions)

2 protocols using nh2 peg12 cooh tbu

1

Synthetic Peptide Production Protocol

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Protected amino acids were purchased from Chem-Impex International (Chicago, IL). H-Cys (Trt)-2-Cl-Trt resin was obtained from Novabiochem (San Diego, CA). 2-(1H-7-Azabenzotriazole-1-yl)-1,1,3,3-tetramethyl uronium hexafluorophosphate methanaminium (HATU) was obtained from Genscript Inc. (Piscataway, NJ). Sulfuric acid, methanol, DMSO, DMF, TFA, isopropyl alcohol, NH2-PEG12-COOH-tBu, diisopropylethylamine (DIPEA), piperidine, CF3COOH, CH2Cl2, K2CO3, tyramine and all other chemical reagents were purchased from Sigma Aldrich. Pure coat Amine 24-well microtiter plates were purchased from BD Biosciences (San Jose, CA). All other cell culture reagents, syringes and disposable items were purchased from VWR (Chicago, IL).
Lv P.C., Putt K.S, & Low P.S. (2016). Evaluation of Nonpeptidic Ligand Conjugates for SPECT Imaging of Hypoxic and Carbonic Anhydrase IX-Expressing Cancers. Bioconjugate chemistry, 27(7), 1762-1769.
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2

Chemical Reagents and Materials

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2-(1H-7-Azabenzotriazole-1-yl)-1,1,3,3-tetramethyl uronium hexafluorophosphate methanaminium (HATU) was obtained from Genscript Inc. (Piscataway, NJ). Sulfuric acid, methanol, DMSO, DMF, TFA, isopropyl alcohol, NH2-PEG12-COOH-tBu, diisopropylethylamine (DIPEA), piperidine, CF3COOH, CH2Cl2, K2CO3, tyramine and all other chemical reagents were purchased from Sigma Aldrich. Purecoat Amine 24-well microtiter plates were purchased from BD Biosciences (San Jose, CA). All other cell culture reagents, syringes and disposable items were purchased from VWR (Chicago, IL).
Lv P.C., Roy J., Putt K.S, & Low P.S. (2016). Evaluation of a Carbonic Anhydrase IX-Targeted Near-Infrared Dye for Fluorescence-Guided Surgery of Hypoxic Tumors. Molecular pharmaceutics, 13(5), 1618-1625.
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