Optokinetic tracking responses (OKTs) were obtained with an optomotor system (Cerebral Mechanics Inc., Lethbridge, Canada). Visual acuity was measured at 100% contrast as previously described [57 -59 ]. Three experienced observers evaluated mice from different litters at P26 (KO, n = 6), P30 (WT, n = 8; KO, n = 2), P36 (KO, n = 2), P45 (WT, n = 7; KO, n = 1), P95–P96 (WT, n = 6; KO, n = 7), and P265 (KO, n = 6).
Optomotor system
Manufactured by Cerebral Mechanics
Sourced in Canada
The Optomotor system is a piece of laboratory equipment used to study the visual responses of animals. It provides a controlled visual environment to measure an animal's reflexive tracking movements in response to visual stimuli. The core function of the Optomotor system is to objectively assess visual perception and oculomotor function in a variety of model organisms.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using optomotor system
1
Visual Acuity Tracking in Mice
2
Optomotor System Measures Visual Thresholds
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Spatial frequency and contrast sensitivity thresholds were measured using an optomotor system (Cerebral Mechanics, Lethbridge, AB, Canada). Two and three month(s)-old rats were placed on a small platform in the center of four computer monitors that formed a virtual drum with a rotating vertical sine wave grating (12°/s (d/s)), as described previously [14 (link)]. Head movements in the same direction as the rotating gratings were considered as positive responses and no response was considered as negative response. Spatial frequency thresholds were determined with an increasing staircase paradigm, starting at 0.042 cycles/deg (c/d) with 100% contrast. Contrast sensitivity thresholds were measured across three spatial frequencies (0.092 c/d). The reciprocal of the contrast sensitivity threshold was used as the contrast sensitivity value at each spatial frequency.
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!