Quantum gx

Manufactured by PerkinElmer

Sourced in United States, France

The Quantum GX is a high-performance micro-computed tomography (micro-CT) imaging system designed for small animal and preclinical research applications. It provides detailed 3D imaging of small samples with excellent image quality and resolution.

Automatically generated - may contain errors

Lab products found in correlation

Analyze 12, by AnalyzeDirect (8 mentions) Analyze 12, by PerkinElmer (7 mentions) Flexivent rodent ventilator, by SCIREQ (4 mentions) Caliper analyze software, by AnalyzeDirect (3 mentions) Laser doppler perfusion imager, by Moor Instruments (1 mentions) Fvb mice, by Charles River Laboratories (1 mentions) Iris 1000, by Thermo Fisher Scientific (1 mentions) Exitron nano 12000, by Miltenyi Biotec (1 mentions) Xtreme bi, by Bruker (1 mentions) Mimics 17, by Materialise (1 mentions) Dataviewer, by Bruker (1 mentions) Nrecon, by Bruker (1 mentions) Ctvox, by Bruker (1 mentions) Amira software, by Thermo Fisher Scientific (1 mentions) In vivo xtreme 2, by Bruker (1 mentions) Isoflurane, by RWD Life Science (1 mentions) Analyze software, by AnalyzeDirect (1 mentions) Mimics medical 21, by Materialise (1 mentions) Analyze 11, by PerkinElmer (1 mentions) 3d viewer, by PerkinElmer (1 mentions)

Spelling variants of this product

Quantum GX microCT Imaging System (32 citations) Quantum GX Micro CT (24 citations) Quantum GX Micro-CT scanner (7 citations) Quantum GX micro-CT system (6 citations) Quantum GX μCT imaging system (5 citations) Quantum GX μCT System (5 citations) Quantum GX μCT (4 citations) Quantum GX microCT software (3 citations) Quantum GX μCT Workstation imaging software (2 citations) Quantum GX software (2 citations)

104 protocols using quantum gx

In Vivo Lung Pathogenesis Monitoring by Micro-CT

Check if the same lab product or an alternative is used in the 5 most similar protocols

In vivo micro-CT was performed to monitor the pathogenesis of lungs during the 14 days. Micro-CT imaging of the mice was performed on days 0, 7, and 14. Before the scan, animals were anesthetized by inhaling a mixture of isoflurane (RWD Life Science Co., Shenzen, China) and oxygen through a nose cone. The micro-CT system (PerkinElmer Quantum G.X., Akron, Ohio, America) was operated with the following parameters: 90 kV, 88 μA, 25 × 25 mm field of view (50 × 50 μm pixel size). Each scan took approximately 4 min. Mice were scanned in a 360-angled position. Images were reconstructed and assessed at a constant window width/window level (400/2200). Micro-CT three-dimensional reconstructions of mice lung tissues were performed and their volumes were calculated. The PerkinElmer Quantum GX self-contained software collected the data of micro-CT. The 3D reconstructive and analysis of CT data were obtained by Bone Microarchitecture Analyze 12.0 [32 (link)].

Li J., Mao M., Li J., Chen Z., Ji Y., Kong J., Wang Z., Zhang J., Wang Y., Liang W., Liang H., Lv L., Liu Q., Yan R., Yuan H., Chen K., Chang Y., Chen G, & Xing G. (2022). Oral Administration of Omega-3 Fatty Acids Attenuates Lung Injury Caused by PM2.5 Respiratory Inhalation Simply and Feasibly In Vivo. International Journal of Molecular Sciences, 23(10), 5323.

+ Open protocol

+ Expand

Establishment of Sarcoma Mouse Model

Check if the same lab product or an alternative is used in the 5 most similar protocols

Five-week-old nude mice (half males and half females) were randomly divided into two groups and anesthetized using sodium pentobarbital (35–40 mg/kg). Approximately 1×10⁶ sh-circ0006571 and sh-NC H1975 cells were suspended in 200 µL of serum-free medium. Then, cells were injected into the left ventricles of the mice to establish SM animal models as previously described (18 (link)). After 4–8 weeks, the mice underwent luciferase signal scanning (Quantum GX, PerkinElmer, Waltham, MA, USA). Mice suspected with SM were subjected to further micro-computed tomography (CT) scanning (Quantum GX, PerkinElmer, USA) and pathological examination. Experiments were performed under a project license (No. 2017-154) granted by Animal Ethics Committee of Zhongshan Hospital, in compliance with national guidelines for the care and use of animals.

Wang H.L., Wang H.R., Liang Y., Hu A.N., Enguita F.J., Zhou X.G, & Dong J. (2020). Hsa_circ_0006571 promotes spinal metastasis through sponging microRNA-138 to regulate sirtuin 1 expression in lung adenocarcinoma. Translational Lung Cancer Research, 9(6), 2411-2427.

+ Open protocol

+ Expand

Non-invasive 3D Grape Berry Imaging

Check if the same lab product or an alternative is used in the 5 most similar protocols

A Quantum GX (PerkinElmer, Waltham, Massachusetts, United States) was used to scan a Shiraz grape berry soon after veraison. A total of 803 two-dimensional projections were acquired with 0.448° angular steps, at 90 kV/88μA. Total scanning time was 14 min. Voxel size was approximately 72 μm. Quantum GX (PerkinElmer, Waltham, Massachusetts, United States) was used for slice reconstructions. The 3D berry model was built in Amira 3.6 (Thermo Fisher Scientific, Bordeaux, France) using the 3D volume rendering module then the clipping Plane module was used to generate a 2D plane for visualizing the berry interior with minimal sample handling and image manipulation.

Xiao Z., Chin S., White R.G., Gourieroux A.M., Pagay V., Tyerman S.D., Schmidtke L.M, & Rogiers S.Y. (2021). Vascular Connections Into the Grape Berry: The Link of Structural Investment to Seededness. Frontiers in Plant Science, 12, 662433.

+ Open protocol

+ Expand

Micro-CT Analysis of Murine Knee Joints

Check if the same lab product or an alternative is used in the 5 most similar protocols

The knee joint images of mice were scanned by micro-CT equipment and a reconstruction system (Quantum GX, PerkinElmer). Data were analyzed using data analysis software (CTAn v1.9) and three-dimensional model visualization software (CTVol v2.0). In addition to the visual assessment of structural pictures, quantitative morphometry indices were determined from microtomographic data based on three-dimensional morphometry. A region of interest was identified between the proximal tibia growth plate and tibial plateau. The following indices were subsequently evaluated: bone volume (BV, mm³), bone volume fraction (BV/TV, %), trabecular thickness (Tb. Th, mm), trabecular separation (Tb. Sp, mm), and trabecular number (Tb. N, 1/mm).

Yi N., Mi Y., Xu X., Li N., Zeng F., Yan K., Tan K., Kuang G, & Lu M. (2022). Baicalein Alleviates Osteoarthritis Progression in Mice by Protecting Subchondral Bone and Suppressing Chondrocyte Apoptosis Based on Network Pharmacology. Frontiers in Pharmacology, 12, 788392.

+ Open protocol

+ Expand

Micro-CT Analysis of Tibial Subchondral Bone

Check if the same lab product or an alternative is used in the 5 most similar protocols

Knees were imaged using a Quantum GX micro‐computed tomography (μCT) scanner (PerkinElmer, Waltham, MA) with the following settings: time = 5 min, voxel size = 7 μm, tube voltage of 90 kV, and tube current = 180 μA. Three‐dimensional reconstructed images were obtained using software AccuCT 1.0 (PerkinElmer), and the proximal tibia was selected for further analysis. Subchondral bone plate thickness was measured in frontal plane cross sections of the weight‐bearing region of the medial tibia plateau.

Ferrao Blanco M.N., Bastiaansen Jenniskens Y.M., Kops N., Chavli A., Narcisi R., Botter S.M., Leenen P.J., van Osch G.J, & Fahy N. (2022). Intra‐articular injection of triamcinolone acetonide sustains macrophage levels and aggravates osteophytosis during degenerative joint disease in mice. British Journal of Pharmacology, 179(11), 2771-2784.

+ Open protocol

+ Expand

Micro-CT Imaging of Bone Microarchitecture

Check if the same lab product or an alternative is used in the 5 most similar protocols

Joints were harvested and imaged in the Quantum GX (Perkin Elmer). Micro-CT imaging and image analysis with the 3D reconstruction of images using in-built analysis software. The X-ray tube settings were 70 kV and 60 mA to scan in standard mode. The duration of imaging at each time point was 2 mins at FOV 72 mm, and an estimated radiation dose of 12-81mGy. The duration of imaging for Bone Microarchitecture Analysis was set for 14 min scan in high-resolution mode at 90KV/88mA with FOV 36 mm and an estimated radiation dose of 221mGy. The reconstructed images were viewed and analyzed using the Analyze Direct 12.0 software (AnalyzeDirect, Inc., Overland Park, KS).

Umar S., Singh A.K., Chourasia M., Rasmussen S.M., Ruth J.H, & Ahmed S. (2022). Penta-o-galloyl-beta-d-Glucose (PGG) inhibits inflammation in human rheumatoid arthritis synovial fibroblasts and rat adjuvant-induced arthritis model. Frontiers in Immunology, 13, 928436.

+ Open protocol

+ Expand

Quantifying Body Composition in Mice

Check if the same lab product or an alternative is used in the 5 most similar protocols

CT scans of mouse carcasses were acquired with a Quantum GX micro-CT (PerkinElmer, Waltham, USA). X-ray settings were at 50 kV with 160 µA current for ideal soft tissue resolution. The full body scan was cropped to the length of the lumbar spine, femur, fat and lean mass was quantified as a representative portion of the whole body [41 (link)] with Analyze 12.0 software (AnalyzeDirect, Overland Park, KS, USA).

Coester B., Lutz T.A, & Le Foll C. (2022). Mouse Microglial Calcitonin Receptor Knockout Impairs Hypothalamic Amylin Neuronal pSTAT3 Signaling but Lacks Major Metabolic Consequences. Metabolites, 12(1), 51.

+ Open protocol

+ Expand

Microarchitecture Analysis of Mouse Femurs

Check if the same lab product or an alternative is used in the 5 most similar protocols

After fixation in 4% paraformaldehyde, the femurs and spines from both the Oc-Cre;Atf7ip^f/f mice and the control mice were scanned by a Quantum GX micro-CT system (PerkinElmer, MA, USA) at a voltage of 90 kV, a current of 88 μA, and a resolution of 12 μm per pixel. A bone region of interest (ROI) was drawn from 0.15 mm proximal to the distal epiphyseal growth plate and extended proximally for 5.4 mm to determine bone volume fraction (BV/TV), trabecular thickness (Tb.Th), trabecular number (Tb.N), trabecular separation (Tb.Sp), cortical area fraction (Ct.Ar/Tt.Ar), and mean cortical thickness (Ct.Th).

Hu G., Shi X., Qu X., Han C., Hu A., Jia Z., Yang J., Liu H, & Wu Y. (2023). Atf7ip Inhibits Osteoblast Differentiation via Negative Regulation of the Sp7 Transcription Factor. International Journal of Molecular Sciences, 24(5), 4305.

+ Open protocol

+ Expand

Evaluating Skeletal Dysplasia in MPS I Mice

Check if the same lab product or an alternative is used in the 5 most similar protocols

To detect whether liver-directed gene therapy could improve skeletal dysplasia in MPS I mice, the zygomata and femora of the mice were scanned using micro-CT (Quantum GX, PerkinElmer, Waltham, MA) 16 weeks after injection (approximately 5 months of age). Images were analyzed using the ImageJ program.

Jin X., Su J., Zhao Q., Li R., Xiao J., Zhong X., Song L., Liu Y., She K., Deng H., Wei Y, & Yang Y. (2022). Liver-directed gene therapy corrects neurologic disease in a murine model of mucopolysaccharidosis type I-Hurler. Molecular Therapy. Methods & Clinical Development, 25, 370-381.

+ Open protocol

+ Expand

Micro-CT Imaging of Carotid and Cerebral Arteries

Check if the same lab product or an alternative is used in the 5 most similar protocols

Carotid and cerebral artery casts were examined using a high-resolution micro-CT imaging system (Quantum GX, Perkin Elmer). Heads to be scanned were placed prone in a specimen tube (diameter 30.7 mm) with the long axis of the head parallel to the tube’s long axis. Micro-CT images were collected over a 4-mm thick section extending from the nose to the back of the neck, scanning in the transverse plane. Each scan was performed with a beam intensity of 80 microamperes, a beam energy of 70 kV, and an isotropic voxel resolution of 50 μm.

Rivera C.P., Li L., Cai S., Pei N., McAlear G.E., Bollavaram K., Aryio O.V., Omojola V.O., Song H., Alfonso A.L., Tan W., Huo Y, & Platt M.O. (2020). Age-dependent characterization of carotid and cerebral artery geometries in a transgenic mouse model of sickle cell anemia using ultrasound and microcomputed tomography. Blood cells, molecules & diseases, 85, 102486.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!