Hemin heme

Rabbit antibody against STAT3, phospho-STAT3, rabbit antibody against AKT, phospho-AKT, anti-NeuN, anti-Iba1, and anti-glial fibrillary acidic protein (GFAP) were purchased from Cell Signaling Technology Inc. (Danvers, MA, USA). Polyclonal antibody to β-actin, lipopolysaccharide (LPS), and sodium fluorescein were purchased from Sigma-Aldrich (St. Louis, MO, USA). Rabbit polyclonal antibodies against claudin5, ZO-1, and phosphorylated ErbB4 (monoclonal) antibody were purchased from Abcam (Cambridge, MA, USA). Rabbit polyclonal antibody against occludin and attachment factor (AF) was purchased from Invitrogen (Waltham, MA, USA). Rabbit antibody against VWF was purchased from Dako (Santa Clara, CA, USA). Anti-ErbB4 (polyclonal) and NRG-1 (polyclonal) antibodies were purchased from Santa Cruz (Dallas, TX, USA). All secondary antibodies used for Western blot were purchased from Calbiochem (La Jolla, CA, USA). Hemin (heme) was purchased from Frontier Scientific (Logan, UT, USA). Recombinant human NRG1β1/HRG1β EGF domain protein (γhNRG-1) and recombinant human CXCL10/IP-10 protein were purchased from R&D systems (Minneapolis, MN). Recombinant human interleukin-1β (IL-1β) was purchased from Millipore (Billerica, MA, USA).

Rabbit antibody STAT3, phospho-STAT3, cleaved caspase-3, rabbit E-cadherin, and rabbit PARP were purchased from Cell Signaling Technology Inc. (Danvers, MA). Forskolin and polyclonal antibody to β-actin were obtained from Sigma-Aldrich (St. Louis, Mo). Mouse monoclonal antibody against α-fodrin was purchased from ABCAM (Cambridge, MA). All secondary antibodies used for Western blot were purchased from Calbiochem (La Jolla, CA). STAT3 siRNA, control siRNA and rabbit polyclonal antibody against p73 were purchased from Santa Cruz (Dallas, TX). Hemin (heme) was purchased from Frontier Scientific (Logan, UT).