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2 protocols using 2 naphthaldehyde

1

Synthesis and Antimicrobial Evaluation

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Starting 1H-indole-3-carboxaldehyde (purity 97%), furfural (99%), 5-methylfurfural (99%), 2-thiophenecarboxaldehyde (98%), 4-pyridinecarboxaldehyde (97%), 2-naphthaldehyde (98%), cyclohexanecarbaldehyde (97%), Lawesson’s reagent (97%), morpholine (99%), benzoyl chloride (99%), iodomethane (99%), and 2-aminobenzenesulfonamide (98%) were purchased from Sigma-Aldrich (St. Louis, MO, USA). The reagents for the analysis of the antimicrobial activity: Cefazolin—MP Biomedicals (Illkirch, France), Cefotaxime—PROMED (Saransk, Russia), Chloramphenicol—AppliChem (Darmstadt, Germany), Amikacin sulfate—Sigma-Aldrich (St. Louis, MO, USA), Fluconazole—Sigma-Aldrich (St. Louis, MO, USA), Amphotericin B—Sigma-Aldrich (St. Louis, MO, USA), Isoniazid—Sigma (St. Louis, MO, USA), LB-broth—VWR (Radnor, PA, USA), and LB-agar—Sigma (St. Louis, MO, USA).
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2

Chitosan-Based Anticancer Compound Synthesis

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Chitosan was obtained from OliZac Technologies Co., Ltd. (Bangkok, Thailand). Cisplatin, benzaldehyde, 2-naphthaldehyde, and octaldehyde were obtained from Sigma Aldrich Chemical Company (St. Louis, MO, USA). Nitric acid was purchased from Merck & Co. (Darmstadt, Germany). Dulbecco’s modified Eagle’s medium (DMEM), fetal bovine serum (FBS) l-glutamine, non-essential amino acids, penicillin–streptomycin, and trypsin–EDTA were acquired from Gibco BRL (Rockville, MD, USA). The reagents used in the assay were of analytical reagent grade.
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