Fentanyl citrate was purchased from Sigma-Aldrich (Castle Hill, NSW). Hydrochloride salts of acetyl fentanyl, 4-fluoroisobutyryl fentanyl, meta-fluoro fentanyl, AH-7921, AH-8529, AH-8533, U-51754, and W-19, along with neat solids of AH-7959, AH-8532, AH-8507, U-49900, and U-50488, were purchased from Sapphire Bioscience (Redfern, NSW). Hydrochloride salts of furanyl fentanyl, acryl fentanyl, 4-methoxybutyryl fentanyl, valeryl fentanyl, butyryl fentanyl, U-47700, and W-18, along with a neat solid of W-15 and MT-45 dihydrochloride hydrate, were purchased from Chiron Chemicals (Hawthorn, VIC). Remifentanil hydrochloride was purchased from GlaxoSmithKline (Boronia, VIC). Citrate salts of carfentanil, sufentanil and α-methyl fentanyl, along with alfentanil hydrochloride, were purchased from Janssen Pharmaceuticals (North Ryde, NSW).
Sufentanil
Manufactured by Johnson & Johnson
Sufentanil is a synthetic opioid analgesic used in general anesthesia and for the management of pain. It is a potent and short-acting medication that can be administered intravenously or intramuscularly. Sufentanil is primarily used in medical settings under the supervision of healthcare professionals.
Automatically generated - may contain errors
2 protocols using sufentanil
1
Comprehensive Fentanyl Analogue Acquisition
2
Comprehensive Pig Anesthesia Protocol
Check if the same lab product or an alternative is used in the 5 most similar protocols
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Anesthesia was induced intramuscularly with a combination of butorphanol (0.17 mg/kg; Alvetra and Werfft AG, Vienna, Austria), medetomidine (0.03 mg/kg; Eurovet Animal Health, Bladel, Netherlands), and midazolam (0.5 mg/kg/h; Nycomed, Linz, Austria) followed by intravenous (ear vein) ketamine (0.07 mg/kg; Pfizer, Vienna, Austria). The trachea was intubated with a 6.5-mm tracheal tube, and volume control ventilation was performed to maintain end-tidal CO2 between 4.5 and 5.5 kPa.
Anesthesia was maintained intravenously with midazolam (0.8 mg/kg/h), sufentanil (8 μg/kg/h; Janssen, Vienna, Austria), and rocuronium (5 mg/kg/h; Organon, Oss, the Netherlands). Catheters were placed by direct preparation and incision of the left external jugular vein and left carotid artery for standard fluid therapy, invasive blood pressure monitoring, and blood withdrawal (according to the standardized pig anesthesia protocol). A 14 Fr catheter was inserted suprapubically into the bladder. Mean arterial pressure, heart rate, oxygen saturation, and ventilation parameters were monitored continuously, while arterial blood gas analysis was performed and lactate was measured at blood sampling time points.
Anesthesia was maintained intravenously with midazolam (0.8 mg/kg/h), sufentanil (8 μg/kg/h; Janssen, Vienna, Austria), and rocuronium (5 mg/kg/h; Organon, Oss, the Netherlands). Catheters were placed by direct preparation and incision of the left external jugular vein and left carotid artery for standard fluid therapy, invasive blood pressure monitoring, and blood withdrawal (according to the standardized pig anesthesia protocol). A 14 Fr catheter was inserted suprapubically into the bladder. Mean arterial pressure, heart rate, oxygen saturation, and ventilation parameters were monitored continuously, while arterial blood gas analysis was performed and lactate was measured at blood sampling time points.
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