Chemiluminescent assays were used for the measurement of Tg [Access Thyroglobulin Assay, Beckman Coulter, Fullerton, CA (functional sensitivity of 0.1 ng/mL)] and TgAb [Immulite 2000, Diagnostic Products Corporation, Los Angeles, CA (reference value of up to 40 IU/mL) or ARCHITECT Anti-Tg, Abbott Laboratories, IL, USA (reference value of up to 4.11 IU/mL)]. Patients with positive TgAb were excluded.
Architect anti tg
Manufactured by Abbott
Sourced in United States
The ARCHITECT Anti-Tg is a laboratory diagnostic instrument used for the quantitative determination of thyroglobulin (Tg) in human serum and plasma. It is designed to provide accurate and reliable test results for the assessment of thyroid function.
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Lab products found in correlation
3 protocols using architect anti tg
1
Thyroglobulin and Anti-Thyroglobulin Assays
2
Thyroglobulin Assay Variability Assessment
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Tg was measured using a chemiluminescent assay (Access Thyroglobulin Assay, Beckman Coulter, Fullerton, CA). In our laboratory, the interassay imprecision profile assessed within 8 months using 10 different serum pools indicated 26% variability at 0.05 ng/mL, 17% at 0.12 ng/mL, 15% at 0.15 ng/mL, 13% at 0.25 ng/mL, 10% at 0.52 ng/mL, 9% at 0.9 ng/mL, 2.1 ng/mL, 7% at 4.2 ng/mL, and 5% at 7.1 and 10.8 ng/mL (functional sensitivity of 0.1 ng/mL (20% variability)). TgAb were measured using a chemiluminescent assay (IMMULITE 2000, Diagnostic Products Corporation, Los Angeles, CA (reference value of up to 40 IU/mL) or Architect Anti-Tg (Abbott Laboratories, IL; reference value of up to 4.11 IU/mL)).
3
Multimodal Imaging for Thyroid Cancer
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US was performed with a linear multifrequency transducer for morphological analysis (B-mode) and for power Doppler evaluation. All suspected lesions apparent on the scans [7, 8] were evaluated by US-guided fine-needle aspiration biopsy. CT with contrast was performed on 5-mm sequential sections. FDG-PET/CT was carried out according to a recommended protocol [9, 10] . All images were analyzed by experienced Radiology or Nuclear Medicine specialists.
Structural disease was defined based on the imaging results, cytology or histology, and/or unequivocal ectopic uptake (excluding false-positive results) on post-therapy WBS (RxWBS) or FDG-PET/ CT. Tumor recurrence was defined as structural disease diagnosed after s-Tg measurement in patients without apparent disease in the initial evaluation.
Chemiluminescent assays were used for the measurement of Tg [Access Thyroglobulin Assay, Beckman Coulter, Fullerton, CA (functional sensitivity of 0.1 ng/ml at our laboratory [11] ) and TgAb [Immulite 2000, Diagnostic Products Corporation, Los Angeles, CA (reference value of up to 40 IU/ml) or ARCHITECT Anti-Tg, Abbott Laboratories, IL, USA (reference value of up to 4.11 IU/ml)].
Structural disease was defined based on the imaging results, cytology or histology, and/or unequivocal ectopic uptake (excluding false-positive results) on post-therapy WBS (RxWBS) or FDG-PET/ CT. Tumor recurrence was defined as structural disease diagnosed after s-Tg measurement in patients without apparent disease in the initial evaluation.
Chemiluminescent assays were used for the measurement of Tg [Access Thyroglobulin Assay, Beckman Coulter, Fullerton, CA (functional sensitivity of 0.1 ng/ml at our laboratory [11] ) and TgAb [Immulite 2000, Diagnostic Products Corporation, Los Angeles, CA (reference value of up to 40 IU/ml) or ARCHITECT Anti-Tg, Abbott Laboratories, IL, USA (reference value of up to 4.11 IU/ml)].
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