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Adh 1

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ADH-1 is a laboratory equipment product manufactured by MedChemExpress. It is a device used for the detection and quantification of alcohol dehydrogenase (ADH) activity in biological samples.

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Lab products found in correlation

Dimethyl sulfoxide (dmso), by Merck Group (2 mentions) Fetal bovine serum (fbs), by Thermo Fisher Scientific (1 mentions) Penicillin streptomycin, by Thermo Fisher Scientific (1 mentions) Rpmi 1640 medium, by Thermo Fisher Scientific (1 mentions) Rucaparib, by Selleck Chemicals (1 mentions) Prexasertib, by MedChemExpress (1 mentions) Olaparib, by Merck Group (1 mentions) Prexasertib, by Merck Group (1 mentions) Rucaparib, by Merck Group (1 mentions) Adh 1, by Merck Group (1 mentions) Olaparib, by Selleck Chemicals (1 mentions) Hydroxyurea hu, by Merck Group (1 mentions)

2 protocols using adh 1

1

Recombinant Protein-Mediated Cell Assays

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Recombinant human N‐cadherin protein was obtained from R&D Systems. DTX, ADH‐1 and Tel were obtained from MedChem Express. All drugs were prepared in dimethyl sulfoxide (DMSO; Sigma‐Aldrich) and diluted with media before each experiment. RPMI‐1640 medium, fetal bovine serum (FBS) and penicillin–streptomycin were purchased from Invitrogen Life Technologies (Gibco, Life Technology).
Khorsand M., Khajeh S., Eslami M., Nezafat N., Ghasemi Y., Razban V, & Mostafavi‐Pour Z. (2022). Telmisartan anti‐cancer activities mechanism through targeting N‐cadherin by mimicking ADH‐1 function. Journal of Cellular and Molecular Medicine, 26(8), 2392-2403.
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2

Preparation and Storage of PARP Inhibitors

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Olaparib (#S1060) and rucaparib (#S1098) were purchased from Selleck Chemicals, Houston, TX. Hydroxyurea (HU; #H8627) was from Sigma-Aldrich. ADH-1 (N-cadherin inhibitor; #HY-13541) and prexasertib (CHK1 inhibitor; #HY-18174) were from MedChemExpress (Monmouth Junction, NJ). 100 mM of Olaparib, 10 mM of rucaparib, HU, ADH-1, and prexasertib were prepared as stocks in dimethyl sulfoxide (DMSO; #S-002-M, Sigma-Aldrich, Saint Louis, MO). All drugs were stored in aliquots at −80 °C until use.
Huang T.T., Burkett S.S., Tandon M., Yamamoto T.M., Gupta N., Bitler B.G., Lee J.M, & Nair J.R. (2022). Distinct roles of treatment schemes and BRCA2 on the restoration of homologous recombination DNA repair and PARP inhibitor resistance in ovarian cancer. Oncogene, 41(46), 5020-5031.
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