All procedures were performed by the same experienced surgeon (YW). SMILE was performed using the VisuMax femtosecond laser system (Carl Zeiss Meditec AG, Jena, Germany) through a 2-mm tunnel incision at the 12-o’clock position with 130 nJ of energy. The lenticule was created as follows: Posterior surface (from the periphery to the center), border, anterior surface (from the center to the periphery), and side-cut incision. The cap diameter was 7.3–7.6 mm, and the cap thickness was 110–120 µm. The lenticule diameter was 6.3–6.6 mm. A blunt spatula is often used to separate the stromal lenticule before its removal through the tunnel incision. Levofloxacin 0.5% eye drops (Carivid; Santen) were instilled four times a day for 3 days before surgery. Postoperatively, topical levofloxacin 0.5% (Carivid; Santen) was prescribed four times a day for 3 days. Fluoroethylene 0.1% eye drops (Flumetholon; Santen) were prescribed four times daily and tapered off every 2–3 weeks. Artificial tear drops were administered four times a day for 3 months.
+ Open protocol