Sorafenib (#T0093L) was purchased from TargetMol (Shanghai, China); lenvatinib (#S1164), brivanib (#S1084) and bafilomycin A1 (#S1413) were purchased from Selleck (Shanghai, China); cisplatin (#P4394), doxorubicin (#D1515), N-acetyl-l -cysteine (NAC, #A7250), and Hoechst (#94403) were purchased from Sigma‒Aldrich (Shanghai, China); canagliflozin (#A11100) was purchased from AdooQ Bioscience (Nanjing, China); and oligomycin (#HY-N6782), antimycin A (#HY-105755), phloretin (#HY-N0142), z-VAD-FMK (#HY-16658B), necrostatin-1 (#HY-15760), and ferrostatin-1 (#HY-100579) were purchased from MedChemExpress (Shanghai, China).
Canagliflozin
Manufactured by Adooq
Sourced in China
Canagliflozin is a laboratory equipment product. It is a sodium-glucose cotransporter-2 (SGLT2) inhibitor, which functions to reduce blood glucose levels in the body.
Automatically generated - may contain errors
Lab products found in correlation
Doxorubicin, by Merck Group (1 mentions)
Lenvatinib, by Selleck Chemicals (1 mentions)
Brivanib, by Selleck Chemicals (1 mentions)
Hoechst, by Merck Group (1 mentions)
Bafilomycin a1, by Selleck Chemicals (1 mentions)
N acetyl l cysteine nac, by Merck Group (1 mentions)
Necrostatin 1, by MedChemExpress (1 mentions)
Cisplatin, by Merck Group (1 mentions)
Ferrostatin 1, by MedChemExpress (1 mentions)
Z vad fmk, by MedChemExpress (1 mentions)
Sorafenib, by Targetmol (1 mentions)
Oligomycin, by MedChemExpress (1 mentions)
Bt474, by American Type Culture Collection (1 mentions)
Dapagliflozin, by Adooq (1 mentions)
Mcf 7, by American Type Culture Collection (1 mentions)
Skbr3, by American Type Culture Collection (1 mentions)
2 protocols using canagliflozin
1
Comprehensive Compound Acquisition Protocol
2
Cell Line Cultivation and SGLT2 Inhibitor Assays
Check if the same lab product or an alternative is used in the 5 most similar protocols
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SKBR3, BT-474, and MCF7 cell lines were purchased from ATCC. SKBR3 cells were grown in RPMI media (11 mM glucose, 2 mM glutamine) supplemented with 10% FBS and 1% gentamycin, while BT-474 and MCF7 cells were grown in DMEM media (25 mM glucose, 4 mM glutamine, 1 mM sodium pyruvate) supplemented with 10% FBS and 1% penicillin/streptomycin. NT2196 and NT2197 cells are immortalized NMuMG mouse mammary epithelial cells that were transformed with an activated variant of Neu (rat form of ErbB2), which has been previously described in [14] (link) and grown in DMEM media (25 mM glucose, 4 mM glutamine, 1 mM sodium pyruvate) supplemented with 10% FBS, 1% penicillin/streptomycin, 10 ug/mL insulin, 20 mM HEPES, pH 7.5, and 2 mM glutamine, to obtain a final glutamine concentration of 6 mM. Canagliflozin and dapagliflozin were purchased from ADOOQ Bioscience. All other reagents were purchased from Sigma unless otherwise stated.
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