Discovery ct750 hd ct scanner

This study was approved by our institutional review board (Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai) and written informed consent was obtained from all patients. From June 2011 to March 2013, 80 patients known or suspected to have Sellar/parasellar tumors underwent multiple-phase CT scanning in the spectral imaging mode, which was performed by using a Discovery CT750 HD CT scanner (GE Healthcare).Patients who had reliable proof of sellar meningiomas and pituitary adenomas were included. Twenty-nine (36%) of the 80 patients were excluded from the study because (a) there was inadequate confirmation of histologic findings (n = 16) (b)Three patients with adenomas were excluded from further analysis because of intratumoral bleeding (n = 3) (c) Other tumors(craniopharyn-giomas,n = 5; squamous-papillary type,n = 2; intrasellar hemangioblastoma,n = 1;intrasellar prostate cancer metastasis,n = 1; suprasellar glioma,n = 1).A total of 51 patients with sellar/parasellar tumors (33 macroadenomas and 18 meningiomas) (age range,38–69 years; mean age, 53 years) were included in our study: 29 were men (age range, 38–61 years; mean age,46 years), and 22 were women (age range,43–69 years; mean age, 57 years). The men were significantly younger than the women (P<0 .05). A total of 51 lesions (mean diameter, 2.3 cm; diameter range, 0.8–2.7 cm) were included.

CT examinations were performed using a 64-row multi-detector CT scanner (Discovery CT750 HD CT Scanner, GE Healthcare, Waukesha, WI, USA). The parameters were as follows: tube voltage, 120 kVp; automatic tube current; rotation time, 0.5 s. A total of 70–100 mL of contrast medium (Ultravist 370, Bayer Schering Pharma, Berlin, Germany) was injected via a peripheral vein at a flow rate of 3.0–3.5 mL/s. Arterial phase CT images were obtained 10 s after attenuation of the abdominal aorta reached 150 Hounsfield units, while the venous phase images were obtained 30 s later. Coronal and sagittal images were reconstructed for each patient.

CT images were obtained using a 16-channel multi-detector CT scanner (Brilliance 16, Philips Medical Systems, Cleveland, OH, USA) or a 64-channel multi-detector CT scanner (Discovery CT750 HD CT Scanner, GE Healthcare Milwaukee, WI, USA). The parameters of the Brilliance 16 scanner were as follows: detector collimation, 1.5 mm; pitch, 1.25:1; tube voltage, 120 kVp; tube current, 80–270 mAs; rotation time, 0.6 s. The parameters of the Discovery CT750 scanner were as follows: detector collimation, 0.625 mm; pitch, 1.375:1; tube voltage, 120 kVp; tube current, 80–270 mAs; rotation time, 0.5 s. For the contrast-enhanced CT study, 80–90 mL of 350 or 370 mg I/mL iodinated contrast agent was injected via a peripheral vein at a flow rate of 3.0–3.5 mL/s, using a dual high-pressure syringe. Dual-phase contrast–enhanced CT images were obtained by scanning the images 10 s and 50–65 s after attenuation of the descending thoracic aorta reached 100 Hounsfield units, using the bolus-tracking technique, for the arterial and venous phases, respectively. Axial, coronal, and sagittal CT images were reconstructed with a 3-mm section thickness and a 3-mm reconstruction interval at an Application Development Workstation (Advantage Windows 4.4; GE Medical Systems, Chicago, IL, USA).

All imaging was conducted on a 256 slice Discovery CT750 HD CT Scanner (GE Healthcare, Waukesha, WI). Chest CT scans with axial technique 5-mm slice thickness were evaluated on a Picture Archiving and Communication System (PACS) workstation (Neusoft Co., China). All images were reviewed on a PACS, using a mediastinal window setting (level, 50 HU; width, 350 HU).